New Insights into Personalized Medicine for Anesthesia and Pain

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Critical Care".

Deadline for manuscript submissions: 25 January 2025 | Viewed by 285

Special Issue Editors


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Guest Editor
Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, 84 Heukseok-ro, Dongjak-gu, Seoul 06911, Republic of Korea
Interests: general anesthesia; cardiac surgery; echocardiography; postoperative pain; biostatistics; epidemiology; systematic review and meta-analysis; lipid; atherosclerosis
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, 84 Heukseok-ro, Dongjak-gu, Seoul 06911, Republic of Korea
Interests: ambulatory anesthesia; airway management; procedural sedation; monitored anesthesia care

Special Issue Information

Dear Colleagues,

Modern medicine is undergoing a profound transformation, with personalized medicine emerging as a key beneficiary of these advancements, representing an approach that tailors medical treatment to the unique genetic, environmental, and lifestyle characteristics of each patient. Our Special Issue, "New Insights into Personalized Medicine for Anesthesia and Pain", explores the latest research and developments that are redefining anesthesia and pain management paradigms.

Personalized medicine marks a shift from the traditional "one-size-fits-all" model to a more nuanced strategy. In anesthesia, this tailored approach promises to optimize drug efficacy, minimize adverse effects, and enhance patient safety and surgical outcomes. In pain management, personalized strategies are essential for addressing the complexities of chronic pain, often requiring multifaceted and individualized treatment plans.

Our Special Issue aims to illuminate the path forward for personalized medicine in anesthesia and pain management. By fostering a deeper understanding of individual patient variability and its implications for clinical practice, we hope to inspire ongoing innovation and collaboration in this dynamic field. Ultimately, our goal is to enhance patient outcomes and quality of life through more targeted and personalized therapeutic strategies.

Prof. Dr. Hyun Kang
Dr. Guen Joo Choi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • new insights
  • personalized medicine
  • anesthesia
  • pain management
  • perioperative analgesia
  • airway management
  • perioperative nausea
  • interventional pain care
  • critical care
  • minimally invasive surgery/robotic surgery
  • mechanical ventilation
  • chronic pain
  • acute pain
  • lumbar/cervical/thoracic/spinal pain
  • musculoskeletal pain

Published Papers (1 paper)

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38 pages, 2117 KiB  
Systematic Review
Effect of Prophylactic Tropisetron on Post-Operative Nausea and Vomiting in Patients Undergoing General Anesthesia: Systematic Review and Meta-Analysis with Trial Sequential Analysis
by In Jung Kim, Geun Joo Choi, Hyeon Joung Hwang and Hyun Kang
J. Pers. Med. 2024, 14(8), 797; https://doi.org/10.3390/jpm14080797 (registering DOI) - 27 Jul 2024
Abstract
This systematic review and meta-analysis of randomized controlled trials (RCTs) with trial sequential analysis (TSA) aimed to comprehensively evaluate and compare the efficacy of the prophylactic administration of tropisetron in the prevention of the incidence of post-operative nausea and vomiting (PONV) in patients [...] Read more.
This systematic review and meta-analysis of randomized controlled trials (RCTs) with trial sequential analysis (TSA) aimed to comprehensively evaluate and compare the efficacy of the prophylactic administration of tropisetron in the prevention of the incidence of post-operative nausea and vomiting (PONV) in patients undergoing surgery under general anesthesia. This study was registered with PROSPERO (CRD42024372692). RCTs comparing the efficacy of the perioperative administration of tropisetron with that of a placebo, other anti-emetic agents, or a combination of anti-emetic injections were retrieved from the databases of Ovid-MEDLINE, Ovid-EMBASE, the Cochrane Central Register of Controlled Trials, and Google Scholar. The frequency of rescue anti-emetic use (RA) and the incidence of PON, POV, and PONV (relative risk [RR]: 0.718; 95% confidence interval [CI] 0.652–0.790; I2 = 0.0, RR: 0.587; 95% CI 0.455–0.757; I2 = 63.32, RR: 0.655; 95% CI 0.532–0.806; I2 = 49.09, and RR: 0.622; 95% CI 0.552–0.700; I2 = 0.00, respectively) in the tropisetron group were lower than those in the control group; however, the incidence of complete response (CR) was higher in the tropisetron group (RR: 1.517;95% CI 1.222–1.885; I2 = 44.14). TSA showed the cumulative Z-curve exceeded both the conventional test and trial sequential monitoring boundaries for RA, PON, POV, and PONV between the tropisetron group and the control group. Thus, the prophylactic administration of tropisetron exhibited superior efficacy in the prevention of PON, POV, and PONV. Furthermore, a lower incidence of RA and a higher incidence of CR were observed with its use. Full article
(This article belongs to the Special Issue New Insights into Personalized Medicine for Anesthesia and Pain)
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