Personalized Approaches in Neurosurgery

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 564

Special Issue Editors


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Guest Editor
Department of Neurosciences, Biomedicine and Movement Sciences, Università di Verona, 37124 Verona, Italy
Interests: neurosurgery; vertebral surgery; artificial intelligence; machine learning; neuronavigation

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Guest Editor
Department of Neurosurgery, M. Bufalini Hospital, AUSL Romagna, 47521 Cesena, Italy
Interests: neurosurgery; artificial intelligence; statistics

Special Issue Information

Dear Colleagues,

Recent advances in medical technology, data availability, and computational capabilities are opening up new possibilities to tailor the diagnostic, therapeutic, and follow-up journey of neurosurgical patients.

The opportunities unveiled by the application of powerful data analysis techniques, the development of personalized surgical plans for brain and spine surgery, the use of 3D printing technology, and the use of personal digital devices to follow patients over time have the potential to improve outcomes while minimizing risks and reducing costs.

In this Special Issue, we aim to provide readers with a collection of articles regarding the evidence collated, as well as current opportunities and challenges, in the development of personalized approaches for diagnosis, treatment, and follow-up in multiple areas of neurosurgery.

We welcome the submission of original basic science and clinical research papers, proof of concept works, technical notes, and review articles targeting any of these topics.

Dr. Alessandro Boaro
Dr. Marco Mammi
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurosurgery
  • neuronavigation
  • neuro-imaging
  • clinical outcomes
  • machine learning

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Published Papers (1 paper)

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20 pages, 2972 KiB  
Review
Intraoperative Monitoring of Sensory Evoked Potentials in Neurosurgery: A Personalized Approach
by Evgeny A. Levin
J. Pers. Med. 2025, 15(1), 26; https://doi.org/10.3390/jpm15010026 - 13 Jan 2025
Viewed by 195
Abstract
Sensory evoked potentials (EPs), namely, somatosensory, visual, and brainstem acoustic EPs, are used in neurosurgery to monitor the corresponding functions with the aim of preventing iatrogenic neurological complications. Functional deficiency usually precedes structural defect, being initially reversible, and prompt alarms may help surgeons [...] Read more.
Sensory evoked potentials (EPs), namely, somatosensory, visual, and brainstem acoustic EPs, are used in neurosurgery to monitor the corresponding functions with the aim of preventing iatrogenic neurological complications. Functional deficiency usually precedes structural defect, being initially reversible, and prompt alarms may help surgeons achieve this aim. However, sensory EP registration requires presenting multiple stimuli and averaging of responses, which significantly lengthen this procedure. As delays can make intraoperative neuromonitoring (IONM) ineffective, it is important to reduce EP recording time. The possibility of speeding up EP recording relies on differences between IONM and outpatient clinical neurophysiology (CN). Namely, in IONM, the patient is her/his own control, and the neurophysiologist is less constrained by norms and standards than in outpatient CN. Therefore, neurophysiologists can perform a personalized selection of optimal locations of recording electrodes, frequency filter passbands, and stimulation rates. Varying some or all of these parameters, it is often possible to significantly improve the signal-to-noise ratio (SNR) for EPs and accelerate EP recording by up to several times. The aim of this paper is to review how this personalized approach is or may be applied during IONM for recording sensory EPs of each of the abovementioned modalities. Also, the problems hindering the implementation and dissemination of this approach and options for overcoming them are discussed here, as well as possible future developments. Full article
(This article belongs to the Special Issue Personalized Approaches in Neurosurgery)
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