Personalized Medicine in Retinal Diseases
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".
Deadline for manuscript submissions: 15 April 2025 | Viewed by 506
Special Issue Editor
2. Achim Wessing Institute for Diagnostic Ophthalmology, Duisburg–Essen University, 45147 Essen, Germany
Interests: age-related macular degeneration (AMD); retinal vascular occlusions; intravitreal injections (IVOM); retinal and vitreous surgery
Special Issue Information
Dear Colleagues,
Retinal diseases are among the most common causes of irreversible blindness. In older adults, it is often the late stage of age-related macular degeneration (AMD), while in working-age individuals, diabetic retinopathy, chronic central serous chorioretinopathy, secondary neovascularizations, or a variety of genetic diseases are more frequently responsible. Since the introduction of anti-VEGF therapy, the prognosis for patients with neovascularizations has significantly improved. However, there is also a great variability in disease progression, with some patients requiring only a few treatments and maintaining good vision in the long term, while others need monthly therapy for decades and experience a significant decline in vision due to complications such as macular hemorrhages, tears of the retinal pigment epithelium, or atrophy of photoreceptors and pigment epithelial cells. Especially with the development of new anti-VEGF agents, the identification of biomarkers that can enable more individualized therapy would be desirable. This also applies to patients with diabetic retinopathy and diabetic macular edema, as well as patients with secondary neovascularization, who are currently treated non-specifically with the same substances. Additionally, with the approval of complement inhibitors, treatment for geographic atrophy (GA) is now available. Even in this late form, several different disease patterns with varying progression rates are already known. Further identification of individual biomarkers could also improve therapy management here. This Special Issue of the Journal of Personalized Medicine aims to present outstanding research dedicated to the individualized investigation of biomarkers for disease progression or therapy response in retinal diseases.
Dr. Henrik Faatz
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- retinal disease
- age-related macular degeneration
- diabetic retinopathy
- gene therapy
- retinal biomarker
- personalized medicine
- retinal imaging
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