Pharmacoepigenetics of Hepatocellular Carcinoma
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Pharmacogenetics".
Deadline for manuscript submissions: closed (31 July 2020) | Viewed by 387
Special Issue Editors
Interests: surgery; transplantation; surgical oncology; oncology; experimental surgery
Special Issues, Collections and Topics in MDPI journals
Interests: surgery; hepatocellular carcinoma; targeted therapies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the past few years, hepatocellular carcinoma has become the most frequent malignant liver disease and the third cause of cancer-related death in Western countries. Despite the introduction of new therapies, treatment outcomes are not encouraging. Τhe prognosis of advanced hepatocellular carcinoma is still dismal, underlying the need for novel effective treatments. In addition to the various risk factors that predispose a person to the development of hepatocellular carcinoma, epigenetic factors also play a functional role in tumor genesis.
On the other hand, rapid and major advances in epigenetics are affecting pharmacology, pharmacogenetics, and pharmacoepigenomics (the application of pharmacoepigenetics in the genome), leading to a new era of treatment possibilities.
The purpose of this Special Issue of the Journal of Personalized Medicine is to target the specific challenges of pharmacoepigenetics and pharmacoepigenomics in the treatment of hepatocellular carcinoma, by identifying the molecular mechanisms of tumor response, considering all the pathways of the regulation of gene expression.
We are inviting submissions of original articles, case reports, and reviews that cover the domain of pharmacoepigenetics of hepatocellular carcinoma, focusing on epigenetic therapies, personalized medicine, and epigenetic biomarkers in drug therapies.
Dr. Christos Damaskos
Dr. Dimitrios Dimitroulis
Dr. Nikolaos Garmpis
Guest Editors
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Keywords
- hepatocellular carcinoma
- pharmacoepigenetics
- epigenomics
- targeted therapy
- personalized medicine
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