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Cataract Surgery: Recent Research and Future Trend

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A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 7549

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Special Issue Editors

Dr. Jin Yang

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Guest Editor

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai 200438, China
Interests: basic and clinical research in the areas of the pathogenesis of age-related cataract; the improvement of the precision of cataract surgery and the application of functional intraocular lens (IOLs); the treatment of various types of complex cataract cases

Dr. Xu Chen

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Guest Editor

1. Department of Ophthalmology & Optometry, Sino United Health Clinics, Shanghai 200336, China
2. Department of Ophthalmology, Shanghai Aier Eye Hospital, Shanghai 200336, China.
3. Aier School of Ophthalmology, Central South University, 506624 Changsha, China
Interests: cataract; refractive disorder; glaucoma; optic nerve disease; cataract surgrey (phaco, FLACS); intraocular lens power calculation; glaucoma surgery, ocular biometry and image

Special Issue Information

Dear Colleagues,

Advances in ophthalmologic surgical approaches such as femtosecond laser-assisted cataract surgery (FLACS) and the developments of optical design and material technology in intraocular lenses led to successfully correcting presbyopia, astigmatism and other refractive errors through the cataract or lens exchange surgery. Newer advanced lens implants provide a fuller range of vision, improving sight at near, intermediate and distance ranges for cataract and presbyopia patients. Even if a skilled surgeon provides these premium IOLs and perfect procedures, there are also the risks of patient dissatisfaction after the surgery. The successful issue of refractive cataract surgery and presbyopia correction include careful patient selection and counseling accuracy biometric measurement, calculation of IOLs power, choosing the right premium IOLs, perfecting surgical techniques and managing dissatisfied patients.

However, the selection and efficacy of functional IOL implantation in presbyopic eyes remain confusing for many surgeons. In addition to so-called premium IOLs such as toric IOLs, multifocal/trifocal IOLs, enhanced depth of focus (EDOF) IOLs, refraction IOLs, and phakic IOLs, there are various types of functional IOLs of different manufacturers, each with its own advantages and disadvantages. Therefore, clinical experience and long-term data are very important.

This research topic aims at collecting high-quality publications on this subject from all over the world, to obtain a good overview of various modern IOLs and their optical principles with advantages and disadvantages, such as contrast sensitivity, aberrations, photic phenomena, etc.

We welcome original research and review articles that include, but are not limited to, the following sub-topics:

Comparison of different types of presbyopia correction IOLs, advantages and disadvantages, and long-term efficacy (multifocal, Trifocal, EDOF, refraction);
Comparison of visual quality between monofocal/multifocal/trifocal IOLs;
Application of toric IOLs;
Comparison of calculation formulas for refractive power calculation;
Femtosecond laser-assisted refractive cataract surgery;
Refractive IOLs in challenge cases;
Complications of cataract surgery;
Posterior capsular opacity;
Surgical treatment and clinical effect of congenital cataract;
Surgical treatment and curative effect observation of various types of lens dislocation.

Dr. Jin Yang
Dr. Xu Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

refractive cataract surgery
presbyopia correction
advanced technology intraocular lenses
multifocal intraocular lenses
visual quality
complication
posterior capsular opacity
congenital cataract
lens dislocation

Published Papers (4 papers)

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Research

12 pages, 1673 KiB

Open AccessArticle

Evaluation of Life Quality of Patients Submitted to Cataract Surgery with Implantation of Trifocal Intraocular Lenses

by Suowang Zhou, Ana Galrão de Almeida Figueiredo, Adilamu Abulimiti, Wilson Takashi Hida and Xu Chen

J. Pers. Med. 2023, 13(3), 451; https://doi.org/10.3390/jpm13030451 - 28 Feb 2023

Cited by 2 | Viewed by 1305

Abstract

This study aimed to evaluate the quality of life and the satisfaction level of Brazilian and Chinese patients who underwent cataract surgery for Acysof IQ PanOptix Model TFNT00 (Alcon Laboratories, Fort Worth, TX, USA) implantation. This retrospective study enrolled 51 patients from China and 51 patients from Brazil. At the 3-month follow-up, uncorrected distance visual acuity (UDVA) at 5 m, uncorrected intermediate visual acuity (UIVA) at 60 cm, and uncorrected near visual acuity (UNVA) at 40 cm were evaluated; Catquest 9SF and the Near Activity Visual Questionnaire (NAVQ) were administered to the patients. The results revealed that the Brazilian patients gained better UDVA and UNVA (p < 0.001), while the Chinese patients gained better UIVA (p = 0.001). With regards to the patients’ overall satisfaction with their current vision, the Brazilian patients scored higher (p = 0.002). In situations related to distant and near vision, the Brazilian patients scored higher, while in situations related to intermediate vision, the Chinese patients scored higher. No differences were found between the gender or age subgroups, but the normal axial length (AL) subgroup showed the highest level of satisfaction (p = 0.002). The patients implanted with TFNT00 IOL obtained excellent objective and subjective outcomes in both cultures. The Brazilian patients showed higher satisfaction with their distant and near vision, while the Chinese patients were more satisfied with their intermediate vision. Full article

(This article belongs to the Special Issue Cataract Surgery: Recent Research and Future Trend)

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11 pages, 2076 KiB

Open AccessArticle

Correction of Asymmetric Bowtie Corneal Astigmatism with a Toric Intraocular Lens: Outcomes and Accuracy of Measurement Modes

by Hao Li, Wenwen He, Donglin Guo, Yanwen Fang, Jiaqi Meng, Keke Zhang, Xiangjia Zhu and Yi Lu

J. Pers. Med. 2023, 13(3), 401; https://doi.org/10.3390/jpm13030401 - 24 Feb 2023

Cited by 2 | Viewed by 1704

Abstract

The outcomes of toric intraocular lens (IOL) implantation in correcting asymmetric bowtie corneal astigmatism remain uncertain. The accurate measurement of corneal astigmatism is essential for surgical planning. In this prospective cohort study, patients with asymmetric or symmetric bowtie corneal astigmatism who underwent toric IOL implantation were recruited. Preoperative corneal astigmatism was measured with an IOLMaster and Pentacam (including the simulated keratometry (SimK), total corneal refractive power (TCRP), and wavefront aberration (WFA) modes). At 3 months after surgery, the refractive outcomes and residual astigmatic refractive errors were compared with patients with symmetric bowtie astigmatism. The prediction errors (the differences between the calculated actual corneal astigmatism and the measured corneal astigmatism) were compared among the different measurement modes in the asymmetric group. There were no differences in residual astigmatism between the asymmetric and symmetric groups. However, the mean absolute residual astigmatic refractive error was greater in the asymmetric group than in the symmetric group (0.72 ± 0.42 D vs. 0.53 ± 0.24 D, p = 0.043). In the asymmetric group, the mean absolute prediction errors for the IOLMaster, SimK, TCRP and WFA modes were 0.53 ± 0.40, 0.56 ± 0.47, 0.68 ± 0.52, and 0.43 ± 0.40 D, respectively. The Pentacam WFA mode was the most accurate mode (p < 0.05). The absolute prediction error of the WFA mode was positively correlated with the total corneal irregular astigmatism higher-order aberrations and coma (r = 0.416 and r = 0.473, respectively; both p < 0.05). Our study suggests toric IOL implantation effectively corrected asymmetric bowtie corneal astigmatism. The Pentacam WFA mode may be the most accurate measurement mode, although its accuracy decreased as asymmetry increased. Full article

(This article belongs to the Special Issue Cataract Surgery: Recent Research and Future Trend)

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10 pages, 1173 KiB

Open AccessFeature PaperArticle

Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification Surgery: Clinical Outcomes with EDOF IOLs

by Pingjun Chang, Fan Zhang, Hongzhe Li, Zhuohan Liu, Siyan Li, Shuyi Qian and Yune Zhao

J. Pers. Med. 2023, 13(3), 400; https://doi.org/10.3390/jpm13030400 - 24 Feb 2023

Cited by 1 | Viewed by 1625

Abstract

In this study, we evaluate and compare the outcomes of conventional phacoemulsification cataract surgery (CPS) and femtosecond laser-assisted cataract surgery (FLACS) with the implantation of an extended depth of field (EDOF) intraocular lens (IOL). A prospective, consecutive cohort study was conducted. Patients were given the option to choose FLACS or CPS and were implanted with an EDOF IOL. Refractive data, visual acuity data, ocular aberration measured with a wavefront aberrometer, and optical quality measured with an optical quality analysis system II were collected at one month postoperatively. A total of 92 eyes of 64 patients were enrolled in this study; 35 eyes of 26 patients were treated with FLACS, whereas 57 eyes of 38 patients were treated with CPS. Uncorrected visual acuity at far, intermediate, and near distance and best-spectacle-corrected visual acuity were not statistically significantly different between the groups (all p > 0.05), nor were the mean cylinder and mean spherical equivalent refraction (both p > 0.05). The FLACS group had a lower ocular trefoil than the CPS group (p = 0.033), and there was no significant difference between the two groups considering other aberration parameters, whether ocular or internal (all p > 0.05). Optical-quality-related parameters showed also no significant difference between the two groups (all p > 0.05). In conclusion, there was no significant difference between FLACS and CPS with implantation of EDOF IOLs in postoperative ocular parameters, refractive outcomes, ocular aberration, optical quality, and aberration parameters, except a lower ocular trefoil in the FLACS group. In terms of these indicators, FLACS does not provide an additional clinical benefit for patients over CPS. Full article

(This article belongs to the Special Issue Cataract Surgery: Recent Research and Future Trend)

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10 pages, 811 KiB

Open AccessArticle

Surgical Outcomes of Lensectomy-Vitrectomy with Primary Intraocular Lens Implantation in Children with Bilateral Congenital Cataracts

by Hongzhe Li, Xiaolei Lin, Xin Liu, Xiyue Zhou, Tianke Yang, Fan Fan and Yi Luo

J. Pers. Med. 2023, 13(2), 189; https://doi.org/10.3390/jpm13020189 - 21 Jan 2023

Cited by 1 | Viewed by 2191

Abstract

In this study, we evaluated the long-term surgical outcomes of lensectomy-vitrectomy with primary intraocular lens (IOL) implantation in children with bilateral congenital cataracts (CCs) and investigated the potential risk factors for low vision. A total of 148 eyes in 74 children who underwent lensectomy-vitrectomy with primary IOL implantation were enrolled in this study. The surgery age was 44.04 ± 14.60 months, with a follow-up period of 46.66 ± 14.34 months. The final BCVA was 0.24 ± 0.32 logMAR, and low vision was found in 22 eyes (14.9%). Postoperative complications requiring additional surgeries included VAO (4 eyes, 5.4%), IOL pupillary captures (2 eyes, 2.0%), iris incarceration (1 eye, 0.7%), and glaucoma (1 eye, 0.7%). A higher incidence of VAO and larger postoperative refractive error was observed in younger children (≤2 years old) than in elder children (>2 years old) (p = 0.003, p = 0.047, respectively). Final BCVA was affected by preexisting comorbidity (p < 0.001), cataract density (p < 0.001), cataract size (p = 0.020), occurrence of postoperative complications (p = 0.011), and ASE (p = 0.008). Multivariate analysis showed that denser cataracts (OR = 9.303, p = 0.035) and preexisting comorbidity (OR = 4.712, p = 0.004) were the significant predictors of low vision. In conclusion, lensectomy-vitrectomy with primary IOL implantation is an effective and safe treatment for CC. The long-term visual outcome is encouraging in children with bilateral CC undergoing this procedure with a low rate of postoperative complications requiring surgeries. Moreover, eyes with denser cataracts and preexisting comorbidity may have a high risk of low vision. Full article

(This article belongs to the Special Issue Cataract Surgery: Recent Research and Future Trend)

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