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New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in...
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New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in Diagnosis, Treatment, and Prognosis

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 864

Special Issue Editors

Dr. Sharaf Eldin Shehada

E-Mail Website
Guest Editor
Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Centre, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany
Interests: cardiac surgery; acute and chronic heart failure; transcatheter valve surgery; echocardiography; myocardial infarction; acute coronary syndrome; end-stage coronary artery disease; short and long-term mechanical circulatory support; protected cardiac surgery; aortic diseases; aortic surgeries
Dr. Anja Osswald

E-Mail Website
Guest Editor
Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University of Duisburg-Essen, University Hospital Essen, 45122 Essen, Germany
Interests: Computational fluid dynamics simulation; aortic dissection

Special Issue Information

Dear Colleagues,

The field of cardiac surgery is continuously evolving, driven by rapid advancements in diagnostic tools, treatment modalities, and our understanding of cardiovascular diseases. This Special Issue is dedicated to highlighting the latest breakthroughs and clinical practices that are shaping the future of cardiovascular medicine. This Special Issue invites submissions on a wide range of topics related to recent advancements in diagnosing and treating coronary artery disease, heart failure, arrhythmias, valvular heart disease, aortic disease, and congenital heart defects. Areas of interest include novel diagnostic techniques, such as advanced imaging and biomarkers, and emerging trends like artificial intelligence and precision medicine. Research on innovative therapeutic approaches, including pharmacological advancements, minimally invasive surgery, and regenerative medicine, is also encouraged. We seek contributions that explore interdisciplinary collaboration, patient-centered care, and the development of prognostic tools, with the aim of enhancing clinical outcomes and shaping the future of cardiovascular care. In this Special Issue, we would like to evaluate all kinds of articles for publication: reviews, original articles, and other types.

Dr. Sharaf Eldin Shehada
Dr. Anja Osswald
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular disease
  • patient-centered care
  • personalized medicine
  • interdisciplinary approaches
  • artificial intelligence
  • prognostic tools
  • minimally invasive surgery
  • robotic surgery
  • bioengineering
  • cardiovascular genomics

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Review

22 pages, 16830 KiB  
Review
Personalized Diagnoses for Those Born with Congenitally Malformed Hearts
by Adrian C. Crucean, Diane E. Spicer, Justin T. Tretter, Rohit Loomba and Robert H. Anderson
J. Pers. Med. 2025, 15(3), 102; https://doi.org/10.3390/jpm15030102 - 4 Mar 2025
Viewed by 619
Abstract
Background/Objectives: It is increasingly realized that the advances in diagnosis and treatment for those born with congenitally malformed hearts have now resulted in avoidance of morbidity being equally as important as avoiding postoperative mortality. Detailed personalized diagnoses will now be key to [...] Read more.
Background/Objectives: It is increasingly realized that the advances in diagnosis and treatment for those born with congenitally malformed hearts have now resulted in avoidance of morbidity being equally as important as avoiding postoperative mortality. Detailed personalized diagnoses will now be key to achieve such improvements. Methods: We have reviewed our own experience in diagnosing major phenotypic variations on selected congenital cardiac malformations, showing that the ability to personalize the findings is at hand, although not always to date universally employed. Results: We have chosen four categories to illustrate how the definitions now provided by the International Nomenclature Society, and incorporated in the 11th iteration of the International Classification of Disease, make it possible to provide personalized diagnoses. The lesions chosen for review are the arrangement of the atrial appendages, the lesions permitting interatrial shunting, the options in the setting of deficient ventricular septation, and the abnormal morphology of the aortic root. We show that not all centers, as yet, are taking advances of these opportunities at hand to tailor the chosen treatments. Conclusions: Detailed phenotypic definitions have now been provided for all the major congenital cardiac malformations. Use of these definitions should now provide personalized medicine for all those born with malformed hearts. As yet, the definitions are not used to their full effect. Full article
(This article belongs to the Special Issue New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in Diagnosis, Treatment, and Prognosis)
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