Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.1
3.0
Journals
JPM
Special Issues
Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings
share announcement

Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 3308

Special Issue Editor

Dr. Jacopo Maria Fontana

E-Mail Website
Guest Editor
Istituto Auxologico Italiano, IRCCS, Research Laboratory in Biomechanics, Rehabilitation and Ergonomics, San Giuseppe Hospital, 28824 Piancavallo (VB), Italy
Interests: whole-body cryostimulation; rehabilitation; obesity and metabolic diseases; musculoskeletal and neurological disorders

Special Issue Information

Dear Colleagues,

Prolonged or repeated cold exposure in humans causes physiological changes occurring in the endocrine, circulatory, neuromuscular, and immunological systems. The application of cold for therapeutic purposes is regularly referred to as cryotherapy and is restricted to the therapeutic use of cold in the management of painful conditions, a centuries-old practice that has already been used by the ancient Greeks. Cryotherapy varies depending on the medium used to achieve the desired purposes: immersion in cold water, the use of ice, or exposure to cold air. Nowadays, partial, local, or whole-body cold exposure is growing significantly and is widely used in the context of sports medicine after physical exercise to reduce effort-related pro-inflammatory responses, to relieve exercise-associated muscle soreness, damage, fatigue, and inflammation, and enhance muscle post-exercise recovery. 

However, a growing body of work has suggested that cryotherapy could play a role as a promising adjuvant therapy under various conditions of rehabilitation interest. In fact, it is currently being used to relieve symptoms in rheumatoid arthritis, fibromyalgia, ankylosing spondylitis, depression, anxiety, multiple sclerosis, sleep disturbances, muscle soreness after strenuous physical exercise, post-COVID-19 syndrome, and obesity. Therefore, we believe that it is important to highlight the potential use of cryotherapy for medical purposes and emphasize its relevance in the field of rehabilitation with the aim of stimulating scientific studies on its efficacy as an adjuvant treatment in various conditions of rehabilitation interest.

The aim of this Special Issue is to publish manuscripts in the form of original research articles, reviews, etc. Authors are encouraged to present their results and discuss original ideas and hypotheses in this field. We expect to stimulate discussions on fundamental questions that can be translated into the clinical context.

Dr. Jacopo Maria Fontana
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cryotherapy
  • local cryotherapy
  • cryostimulation
  • partial/local/whole-body cryostimulation
  • par-tial/local/whole-body cryotherapy
  • personalized rehabilitation
  • multidisciplinary rehabilitation
  • cold therapy
  • cold exposure
  • adjuvant therapy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

13 pages, 2441 KiB  
Article
High-Intensity Interval Training, but Not Whole-Body Cryostimulation, Affects Bone-Mechanosensing Markers and Induces the Expression of Differentiation Markers in Osteoblasts Cultured with Sera from Overweight-to-Obese Subjects
by Marta Gomarasca, Ewa Ziemann, Veronica Sansoni, Marta Flis, Silvia Perego, Joanna Jaworska, Laura Gerosa, Martina Faraldi and Giovanni Lombardi
J. Pers. Med. 2024, 14(10), 1015; https://doi.org/10.3390/jpm14101015 - 24 Sep 2024
Viewed by 508
Abstract
Background/Objectives: Although there have been some clinical observations made, the mechanistic effects on bone metabolism of whole-body cryostimulation and high-intensity interval training (HIIT), either alone or in combination, are still debated. Here, we have investigated their effects on circulating osteo-immune and bone metabolic [...] Read more.
Background/Objectives: Although there have been some clinical observations made, the mechanistic effects on bone metabolism of whole-body cryostimulation and high-intensity interval training (HIIT), either alone or in combination, are still debated. Here, we have investigated their effects on circulating osteo-immune and bone metabolic markers (osteopontin, osteocalcin, sclerostin, dikkopf-related protein 1, and fibroblast-growth factor 23) and their potential effects on osteoblast differentiation and function, in vitro, by treating SaOS-2 osteoblast-like cells with the sera obtained from the subjects who had undergone the different interventions or untreated control subjects. Methods: Sixty-seven inactive, overweight-to-obese participants (body mass index = 31.9 ± 5.0 kg·m−2, 42 ± 13 years old) were recruited and randomly assigned to one group: control (CTRL, n = 14), training (HIIT, 6 sessions, n = 13), WBC (CRYO, 10 sessions, n = 17) or training combined with WBC (CRYO-HIIT, n = 23). The interventions lasted 14 days. Results: While circulating markers analysis revealed more protective potential against resorption in HIIT than in WBC alone or combined, gene expression from in vitro analysis showed an induction of late bone metabolic markers in the HIIT group. Conclusions: These data suggest a potentially protective effect of HIIT in bone against resorption, while WBC maintains homeostasis by preventing any resorptive phenomena and limiting any anabolic activity even when stimulated by intensive exercise. Full article
(This article belongs to the Special Issue Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings)
►▼ Show Figures

Figure 1

12 pages, 1366 KiB  
Article
Whole-Body Cryostimulation: An Effective Complementary Treatment in Fibromyalgia? A Follow Up Study
by Federica Verme, Neža Majdič, Giuseppe Modaffari, Angelo Alito, Alessandra Scarpa, Paolo Piterà, Amelia Brunani, Jacopo Maria Fontana and Paolo Capodaglio
J. Pers. Med. 2024, 14(8), 836; https://doi.org/10.3390/jpm14080836 - 7 Aug 2024
Viewed by 2062
Abstract
Recent evidence suggests that whole-body cryostimulation (WBC) may be beneficial for patients with fibromyalgia (FM), but little is known about the duration of such effects. The purpose of this study was to verify the duration of clinical–functional benefits after one cycle of WBC. [...] Read more.
Recent evidence suggests that whole-body cryostimulation (WBC) may be beneficial for patients with fibromyalgia (FM), but little is known about the duration of such effects. The purpose of this study was to verify the duration of clinical–functional benefits after one cycle of WBC. We conducted a follow-up study on the medium and long-term effects of WBC on well-being, use of pain-relieving/anti-inflammatory medications, pain level, fatigue, sleep quality, and psychological aspects such as mood and anxiety. Twelve months after discharge, we administered a 10 min follow-up telephone interview with FM patients with obesity who had undergone ten 2 min WBC sessions at −110 °C as part of a multidisciplinary rehabilitation program (n = 23) and with patients who had undergone rehabilitation alone (n = 23). Both groups reported positive changes after the rehabilitation program, and similar results regarding fatigue, mood, and anxiety scores; however, the implementation of ten sessions of WBC over two weeks produced additional benefits in pain, general well-being status, and sleep quality with beneficial effects lasting 3–4 months. Therefore, our findings suggest that adding WBC to a rehabilitation program could exert stronger positive effects to improve key aspects of FM such as general well-being, pain level, and sleep quality. Full article
(This article belongs to the Special Issue Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings)
►▼ Show Figures

Figure 1

Other

Jump to: Research

10 pages, 648 KiB  
Case Report
The Effect of Therapeutic Exercise and Local Cryotherapy on Lower Limb Enthesitis in Non-Radiographic Axial Spondyloarthritis: A Case Report
by Angelo Alito, Rossella Talotta, Valeria D’Amico, Daniela Amato, Demetrio Milardi and Paolo Capodaglio
J. Pers. Med. 2024, 14(10), 1035; https://doi.org/10.3390/jpm14101035 - 28 Sep 2024
Viewed by 418
Abstract
Background: Enthesitis is a common feature of spondyloarthritis and can severely impair the patient’s quality of life. International guidelines recommend multidisciplinary management of this condition, combining physical and pharmacological interventions. In this case report, we demonstrate clinical and ultrasonographic improvements by prescribing local [...] Read more.
Background: Enthesitis is a common feature of spondyloarthritis and can severely impair the patient’s quality of life. International guidelines recommend multidisciplinary management of this condition, combining physical and pharmacological interventions. In this case report, we demonstrate clinical and ultrasonographic improvements by prescribing local cryotherapy and therapeutic exercise alone in an adult woman with non-radiographic axial SpA (nRX-AxSpA) complaining of heel enthesitis. Methodology: A personalized program was prescribed that focused on reducing pain, joint stiffness, and muscle tightness, improving strength and endurance. Pain, function, and degree of disability were assessed using the Numerical Rating Scale, the Victorian Institute of Sport Assessment-Achilles, the single-leg heel lift test, and the Foot Function Index. In addition, lower limb muscle strength was measured using a dynamometer and enthesitis was assessed ultrasonographically using the Glasgow Ultrasound Enthesitis Score System. Results: Benefits were evident as early as week 5 and persisted at 3 months on ultrasound assessment. No side effects were reported. Discussion: To the best of our knowledge, this is the first report of prescribing such a strategy in a patient with nRX-AxSpA. Given the good tolerability, this intervention could be considered in patients with contraindications to pharmacologic approaches. Full article
(This article belongs to the Special Issue Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop