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Emergency Medicine: Updates on Personalized Diagnosis, Treatment, and Management
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Emergency Medicine: Updates on Personalized Diagnosis, Treatment, and Management

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Critical Care".

Deadline for manuscript submissions: 25 May 2026 | Viewed by 89

Special Issue Editor

Dr. Gabriele Savioli

E-Mail Website
Guest Editor
Department of Emergency Medicine, Foundation Policlinico San Matteo University Hospital, 27100 Pavia, Italy
Interests: ED management; triage; hospital and ED crowding; maxi-emergency
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The world of emergency medicine is undergoing a major reorganization and is facing new challenges in increasingly crowded hospitals by honing skills for the recognition and treatment of critical conditions of increasingly complex patients. It is necessary to analyze this system and its critical aspects in order to rethink its structure and function. It is necessary to accept that different types of emergencies may need to be managed individually. In this scenario, it will be necessary to design new systems that recognize and treat general acute health situations, as well as those that will become more frequent, such as in instances of unrecognized geriatric health problems. It will also be essential to establish optimal diagnostic and therapeutic pathways for both acute and rare diseases. Some categories of fragile patients deserve specific attention; for example, HIV patients or cancer patients (these patients often need to be treated urgently). This will also lead to drastic changes in the training methods of health professionals, including students, and in the design of emergency departments. In these scenarios, reflections on the legal aspects of accessibility to care can be an interesting starting point of discussion.

I look forward to receiving your contributions.

Dr. Gabriele Savioli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ED crowding
  • maxi emergencies
  • major trauma
  • geriatric health problems
  • fragile patients
  • personalized management

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Published Papers (1 paper)

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Research

13 pages, 249 KB  
Article
Weekend Effect and Predictors of Mortality for Patients Presenting to Emergency Department with COVID-19 Infection
by Amteshwar Singh, Jerome Gnanaraj, Evani Jain, Japleen Kaur and Waseem Khaliq
J. Pers. Med. 2025, 15(9), 402; https://doi.org/10.3390/jpm15090402 - 1 Sep 2025
Abstract
Background: Weekend presentation to the emergency department (ED) has been associated with increased morbidity and mortality in various clinical settings. However, the literature is scant whether such an effect exists for patients presenting with COVID-19 infection. Additionally, comparative analyses of mortality predictors in [...] Read more.
Background: Weekend presentation to the emergency department (ED) has been associated with increased morbidity and mortality in various clinical settings. However, the literature is scant whether such an effect exists for patients presenting with COVID-19 infection. Additionally, comparative analyses of mortality predictors in COVID-19 patients evaluated at the emergency department need further exploration. Methods: This retrospective cohort study examined factors associated with mortality among adult patients (aged ≥ 18 years) who presented with COVID-19 to the emergency departments of five hospitals within the Johns Hopkins Health System (combined capacity: 2513 beds) between March 1 and 4 May 2020. Data were extracted from electronic health records. Multivariable logistic regression was utilized to assess the relationship between mortality and a range of variables, including sociodemographic characteristics, clinical presentation, laboratory parameters, pre-existing comorbidities, and weekend versus weekday presentation. Results: Of the 2767 patients, 685 (25%) presented to the emergency department on weekends. Compared to weekday presenters, weekend patients were more likely to be hospitalized (64%), and these patients had a mean symptom duration of 5 days (SD ± 6). Weekend presenters also exhibited higher rates of clinical frailty, dehydration, hypoxia, and respiratory distress upon arrival. In multivariable logistic regression analysis adjusting for sociodemographic characteristics, clinical risk factors, and laboratory findings, independent predictors of increased mortality included absence of a primary care provider (OR 3.47; 95% CI: 2.37–5.07), peripheral oxygen saturation (SpO2) < 95% at presentation (OR 1.46; 95% CI: 1.001–2.12), and hyperglycemia (OR 2.13; 95% CI: 1.25–3.65). Notably, the presence of crackles on physical examination demonstrated a trend toward reduced mortality (OR 0.47; 95% CI: 0.24–0.92). Conclusions: While weekend presentation was associated with higher hospitalization rates among patients with COVID-19, it did not independently predict increased mortality. Absence of a primary care provider, hypoxia, and hyperglycemia at presentation emerged as strong, independent predictors of mortality in the ED setting. Race, gender, and obesity were not significantly associated with mortality in this cohort, warranting further investigation. These findings may support more effective triage and risk stratification strategies in current and future public health emergencies. Full article
(This article belongs to the Special Issue Emergency Medicine: Updates on Personalized Diagnosis, Treatment, and Management)
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