Pancreatic Disease Research and Personalized Medicine in Adults

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (1 July 2022) | Viewed by 3370

Special Issue Editor


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Guest Editor
Clinic of General, Visceral and Vascular Surgery, Jena Friedrich Schiller Universitaet, Fürstengraben 1, 07743 Jena, Germany
Interests: surgery; surgical oncology; colorectal surgery; hepatobiliary surgery; liver transplantation; gastroenterology

Special Issue Information

Dear Colleagues,

The incidence of pancreatic malignancies is increasing over the past years. However, benign diseases of the pancreas are more often being diagnosed and many clinicians are faced with an increasing number of patients with pancreatic diseases. The improvement of conventional treatment methods and the application of new therapies are the key to improving efficacy. Therefore, precision medicine is applied to pancreatic diseases. The diagnosis and treatment of the disease are particularly important.

This Special Issue focuses on the experimental research, diagnosis, and treatment of pancreatic diseases in adults.

Conventional treatment methods, including chemotherapy, are even nowadays mostly only palliative; the mortality rate has not decreased in the past decade, despite improvements. Recently, there have been many advances in the pathological research of pancreatic tumors, genomics, and transcriptomics. Artificial intelligence technology is also developing rapidly in the management of pancreatic diseases, guiding precision medicine in clinical, endoscopic, and radiological environments.

We search for papers dealing with experimental approaches reflecting pancreatic diseases but also for papers dealing with new insights in diagnosis of pancreatic diseases as well as therapeutic measures. We welcome both studies for benign and malignant pancreatic diseases.

Prof. Dr. Falk Rauchfuss
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pancreas carcinoma
  • neuroendocrine tumor
  • pancreas resection
  • pancreatitis
  • rare diseases
  • animal experiments
  • cell culture
  • precision medicine

Published Papers (1 paper)

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13 pages, 4637 KiB  
Review
Risk Factors for Pancreatic Cancer: Emerging Role of Viral Hepatitis
by Gina Gheorghe, Camelia Cristina Diaconu, Vlad Ionescu, Gabriel Constantinescu, Nicolae Bacalbasa, Simona Bungau, Mihnea-Alexandru Gaman and Madalina Stan-Ilie
J. Pers. Med. 2022, 12(1), 83; https://doi.org/10.3390/jpm12010083 - 10 Jan 2022
Cited by 16 | Viewed by 2908
Abstract
Pancreatic cancer is one of the most aggressive malignant neoplastic diseases. The incidence and mortality rates of this disease vary depending on geographical area, which might be explained by the different exposure to risk factors. To improve the prognosis of patients with pancreatic [...] Read more.
Pancreatic cancer is one of the most aggressive malignant neoplastic diseases. The incidence and mortality rates of this disease vary depending on geographical area, which might be explained by the different exposure to risk factors. To improve the prognosis of patients with pancreatic cancer, different approaches are needed for an earlier diagnosis. Identification of risk factors and implementation of screening strategies are essential for a better prognosis. Currently, the risk factors for pancreatic cancer fall into two broad categories, namely extrinsic and intrinsic factors. Extrinsic factors include alcohol consumption, smoking, a diet rich in saturated fats, and viral infections such as chronic infection with hepatitis B and C viruses. The pathophysiological mechanisms explaining how these hepatotropic viruses contribute to the development of pancreatic cancer are not fully elucidated. The common origin of hepatocytes and pancreatic cells in the multipotent endodermal cells, the common origin of the blood vessels and biliary ducts of the pancreas and the liver, or chronic inflammatory changes may be involved in this interaction. A careful monitoring of patients with viral liver infections may contribute to the early diagnosis of pancreatic cancer and improve the prognosis of these patients. Full article
(This article belongs to the Special Issue Pancreatic Disease Research and Personalized Medicine in Adults)
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