Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances and Perspectives in Ophthalmology: Progress and Modern Challenges
edited by
submission deadline 30 Apr 2026 | 14 articles | Viewed by 40448 | Submission Open
Keywords: clinical ophthalmology; eye diseases; retinal diseases; corneal diseases; optic nerve diseases; glaucoma; dry eye disease; maculopathies; choroidal diseases; ocular oncology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine for Otolaryngology (ENT)
edited by
submission deadline 30 Apr 2026 | 11 articles | Viewed by 28021 | Submission Open
Keywords: otology; head and neck cancer; rhinology; laryngology; facial plastic surgery; sleep medicine; biomarker; clinical genomics; artificial intelligence
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Approaches to Spine Surgery: Innovations and Future Directions
edited by and
submission deadline 30 Apr 2026 | 8 articles | Viewed by 25749 | Submission Open
Keywords: personalized medicine; spine surgery; precision imaging; minimally invasive techniques; 3D printing in orthopedics; biomarkers in spinal health; artificial intelligence in surgery; robotics in spine surgery; genomics and spinal disorders; pain management and rehabilitation; surgical navigation systems; biocompatible materials for implants; patient-specific surgical planning; regenerative medicine in spine health; future trends in spinal surgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine for Gastrointestinal Diseases
edited by Athanasios Syllaios and
submission deadline 30 Apr 2026 | 5 articles | Viewed by 7466 | Submission Open
Keywords: personalized medicine; molecular mechanisms; gastrointestinal diseases; artificial intelligence; diagnosis and treatment; gastrointestinal cancer
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Personalized Cosmetic and Restorative Dentistry
edited by Vlatka Debeljak and Daniela Kovacevic Pavicic
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2400 | Submission Open
Keywords: advances in cosmetic dentistry; advances in esthetic dentistry; advances in dental technology; advances in digital tools
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Neuroinflammation and Multiple Sclerosis: Pathogenesis to Personalized Therapy
edited by Alenka Horvat Ledinek
submission deadline 10 May 2026 | 1 articles | Viewed by 1486 | Submission Open
Keywords: personalized medicine; multiple sclerosis; neuroinflammation; biomarkers; patient stratification; mechanism-based therapy; neuroimaging; genomic profiling; clinical decision-making
(This special issue belongs to the Section Mechanisms of Diseases)
Advances in Precision Medicine for Gastrointestinal Cancers
edited by
submission deadline 10 May 2026 | Viewed by 201 | Submission Open
Keywords: gastrointestinal cancer; precision medicine; personalized medicine; diagnostic imaging; genomic testing; proteomics; molecular targeted drug; immune checkpoint inhibitors; artificial intelligence
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Current Trends in Cataract Surgery
edited by Romina Fasciani and
submission deadline 15 May 2026 | 4 articles | Viewed by 9189 | Submission Open
Keywords: refractive cataract surgery; visual quality; dry eye; side effects; advanced technology intraocular lenses; AMD IOLs
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Bioethics in Personalized Medicine and Precision Medicine
edited by Michael Igoumenidis and
submission deadline 15 May 2026 | Viewed by 322 | Submission Open
Keywords: bioethics; equity; genetic discrimination; health disparities; individualized care; predictive analytics
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Trends and Future Development in Precision Medicine
edited by Candan Hizel
submission deadline 20 May 2026 | 1 articles | Viewed by 2097 | Submission Open
Keywords: precision/personalized medicine/genomic medicine; omics disciplines; pharmacogenomics/pharmacogenetics; systems biology; bioinformatics; big data; complex diseases; rare diseases; inter-disciplinarity; public health genomics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Novel Studies and Therapeutic Options for Skin Disease
edited by Leszek Blicharz and
submission deadline 20 May 2026 | Viewed by 925 | Submission Open
Keywords: dermatology; genodermatoses; inflammatory skin diseases; personalized treatment; skin; skin cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Retinal Diseases: Mechanisms, Diagnosis and Treatments submission deadline 25 May 2026 | 6 articles | Viewed by 13173 | Submission Open
Keywords: multimodality; vitreo-retinal surgery; anti-VEGF agents; genetic treatments
(This special issue belongs to the Section Mechanisms of Diseases)
Advancements in Psychiatry: Exploring New Horizons in Mental Health submission deadline 25 May 2026 | 3 articles | Viewed by 4699 | Submission Open
Keywords: psychopharmacology; antipsychotics; antidepressants; major depressive disorder; schizophrenia spectrum disorders; anxiety disorders; gut microbiota; neuromodulation; nutritional psychiatry; nosographic classifications; biomarkers; new diagnoses; food addiction; behavioral addictions; gaming disorder; internet use disorder; gambling disorder; gut microbiota; avatar therapy; mindfulness therapy; transcranial magnetic stimulation
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Challenges and New Strategies in the Management of Gliomas submission deadline 25 May 2026 | 1 articles | Viewed by 4265 | Submission Open
Keywords: brain tumors; human; mammals; astrocytes; microglia; oligodendroglia; neuroanatomy; neuropeptides; imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Innovative Research and Therapeutics in Pediatric and Adolescent and Young Adult (AYA) Oncology submission deadline 25 May 2026 | 1 articles | Viewed by 1731 | Submission Open
Keywords: target therapy; molecular research; rare tumors; hematologic malignancies; solid tumors
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Emergency Medicine: Updates on Personalized Diagnosis, Treatment, and Management
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 1384 | Submission Open
Keywords: ED crowding; maxi emergencies; major trauma; geriatric health problems; fragile patients; personalized management
(This special issue belongs to the Section Personalized Medical Care)
Breast Cancer: Molecular Highlights, Emerging Therapies, and Promising Strategies
edited by
submission deadline 25 May 2026 | Viewed by 280 | Submission Open
Keywords: breast cancer; metastatic breast cancer; biomarkers; molecular profiling; immune landscape; genomics; personalized treatment; targeted therapy
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Oral and Maxillofacial Diseases
edited by , Waldemar D. Polido and
submission deadline 25 May 2026 | Viewed by 244 | Submission Open
Keywords: oral and maxillofacial surgery; personalized medicine; genomic profiling in oral diseases; molecular diagnosis; targeted therapy; oral and maxillofacial diseases; oral surgery; enhanced recovery after surgery (ERAS); precision medicine; artificial intelligence
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine for Maternal–Fetal Medicine
edited by
submission deadline 25 May 2026 | Viewed by 213 | Submission Open
Keywords: pregnancy complication; endometriosis in pregnancy; premature birth; genomics; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cutting-Edge Innovations in Hip and Knee Joint Replacement
edited by Matteo Innocenti and Roberto Civinini
submission deadline 27 May 2026 | 5 articles | Viewed by 6888 | Submission Open
Keywords: primary or revision total hip arthroplasty; hip resurfacing; primary or revision total knee arthroplasty; unicompartimental/bicompartimental knee replacement; patient-specific instrumentation (PSI); custom-made/personalized implants; robot-assisted surgery; mixed/augmented reality; artificial intelligence (AI); personalized surgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Artificial Intelligence for Personalized Medicine: Bridging Innovative Technologies and Patient-Centric Care submission deadline 31 May 2026 | 8 articles | Viewed by 20008 | Submission Open
Keywords: artificial intelligence (AI); personalized medicine; AI-driven diagnostics and treatment; personalized treatment; AI applications; genomics; proteomics and other omics technologies; machine/deep learning algorithms; drug discovery and development for personalized therapy; complex genomic data and mutation patterns; wearables and ioT devices
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings submission deadline 31 May 2026 | 4 articles | Viewed by 19124 | Submission Open
Keywords: cryotherapy; local cryotherapy; cryostimulation; partial/local/whole-body cryostimulation; par-tial/local/whole-body cryotherapy; personalized rehabilitation; multidisciplinary rehabilitation; cold therapy; cold exposure; adjuvant therapy
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Trends and Challenges in Pharmacogenomics Research
edited by
submission deadline 31 May 2026 | 7 articles | Viewed by 14366 | Submission Open
Keywords: drug development; polygenic risk scores; diversity and inclusion; complex disease management; implementation science; genetic ancestry; special populations; rare variants
(This special issue belongs to the Section Pharmacogenetics)
Surgical Innovation and Advancement in Limb Extremities submission deadline 31 May 2026 | 4 articles | Viewed by 11503 | Submission Open
Keywords: hand surgery; wrist surgery; ankle surgery; foot surgery; innovation; joint replacement; arthroscopy; flaps; microsurgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Exploring Interventional Radiology: New Advances and Prospects
edited by
submission deadline 31 May 2026 | 6 articles | Viewed by 7346 | Submission Open
Keywords: interventional radiology; embolization; innovative techniques; minimally invasive procedures; long-term safety; prostate cancer; vascular anomalies; clinical outcomes; health economics; epidemiology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Orthodontics and Oral Surgery in Personalized Medicine: 2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 5305 | Submission Open
Keywords: oral surgery; orthodontic; aligners; maxillo facial surgery; dental disease; dental materials; orthodontic diseases; periodontology; oral implantology; regenerative tissue; growth factor; stem cells; bone regeneration; tissue regeneration; engineering; intraoral scan; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Arthroplasty and Personalized Medicine: Updates and Challenges
edited by and Michela Saracco
submission deadline 31 May 2026 | 2 articles | Viewed by 4157 | Submission Open
Keywords: personalized medicine; personalized orthopedic surgery; primary and revision arthroplasties; personalized orthoplastic approach; personalized orthobiology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Traumatic Brain Injury: Complications and Outcomes of Precision Medicine submission deadline 31 May 2026 | 1 articles | Viewed by 3836 | Submission Open
Keywords: biomarkers; genetic polymorphisms; neuromonitoring; neuroradiology; microbiome
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Advances in Metabolic Diseases Diagnostics and Treatment: From Basic Research to Clinical Practice submission deadline 31 May 2026 | 1 articles | Viewed by 3164 | Submission Open
Keywords: metabolic disease; inherited metabolic disease; mitochondrial metabolism; metabolomics; multi-omics; biomarkers
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Thoracic Oncology: Targeted Therapies and Personalized Treatment Strategies
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2386 | Submission Open
Keywords: thoracic oncology; thoracic tumors; translational research; target therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Orthopedics and Traumatology: Progress and Challenges
edited by Federico Canavese, and
submission deadline 31 May 2026 | 1 articles | Viewed by 1526 | Submission Open
Keywords: orthopedics; traumatology; personalized medicine; patient-specific treatments; custom implants; regenerative medicine; biomechanics; predictive modeling; personalized rehabilitation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine for Breast Cancer: Update and New Challenge
edited by Arya Mariam Roy and Daniel Stover
submission deadline 31 May 2026 | Viewed by 452 | Submission Open
Keywords: personalized Medicine; tumor genomics; biomarker discovery; targeted therapy therapy resistance antibody-drug conjugates; genomic profiling; liquid biopsy; therapeutic sequencing
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 May 2026 | 1 articles | Viewed by 322 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Geriatrics and Gerontology: Prevention, Treatment and Multidisciplinary Research
edited by Dana Crisan, Valer Donca and
submission deadline 31 May 2026 | Viewed by 270 | Submission Open
Keywords: geriatrics; geriatric medicine; gerontology; personalized medicine; elderly; frailty; geriatric patients; aging process; cardiovascular diseases; renal system diseases; rheumatologic diseases; pharmacology; infectious diseases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Advances in Cardiothoracic Surgery: Personalized Treatment and Management submission deadline 31 May 2026 | Viewed by 258 | Submission Open
Keywords: complex aortic surgery; valvular heart disease; endocarditis; individualized; open heart surgery; minimally invasive techniques; artificial intelligence
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Heart Failure: Personalized Diagnosis, Treatment and Management
edited by Edgardo J. Kaplinsky
submission deadline 31 May 2026 | Viewed by 245 | Submission Open
Keywords: heart failure; personalized diagnosis; heart disease; myocardial structure; myocardial function; cardiomyopathies; chronic heart failure; clinical cardiology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Diagnostics and Therapeutics in Otolaryngology
edited by Enrique Zapater-Latorre and
submission deadline 31 May 2026 | Viewed by 221 | Submission Open
Keywords: otology; head and neck cancer; personalized medicine; rhinology; laryngology; facial plastic surgery; sleep medicine; artificial intelligence; precision diagnosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Diagnosis and Treatment for Head and Neck Cancer
edited by
submission deadline 10 Jun 2026 | 1 articles | Viewed by 1039 | Submission Open
Keywords: biomarker; precision diagnosis; head and neck cancer; oral cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Diabetes and Its Complications: From Research to Clinical Practice submission deadline 20 Jun 2026 | 3 articles | Viewed by 7099 | Submission Open
Keywords: diabetes; cardiovascular diseases; kidney disorders; liver diseases; obesity; aging; diabetes medications
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Multiple Pregnancies: Optimal Follow-Up, Early Detection and Management of Complications, and Appropriate Mode and Time of Delivery submission deadline 20 Jun 2026 | 2 articles | Viewed by 3417 | Submission Open
Keywords: multiple pregnancy; twin pregnancy; triplet pregnancy; monochorionic pregnancy; monochorionic twins; monochorionic monoamniotic pregnancy; monochorionic diamniotic pregnancy; dichorionic diamniotic pregnancy; quadruplet pregnancy; chorionicity; amnionicity; conjoined twins; in vitro fertilization; assisted reproductive techniques; advanced maternal age; natural conception; pregnancy dating; aneuploidy screening; twin-to-twin transfusion syndrome (TTTS); fetal growth restriction (FGR); selective fetal growth restriction (sFGR); twin anemia-polycythemia sequence (TAPS); twin reversed arterial perfusion sequence (TRAP); fetoscopy; laser ablation; fetal laser therapy; laser therapy; bipolar cord coagulation; radiofrequency ablation; selective feticide; elective fetal reduction; elective termination of pregnancy; discordant fetal anomaly; structural abnormalities; single intrauterine fetal demise; cerclage; threatened preterm labor; preterm birth; preeclampsia; gestational hypertension; gestational diabetes; fetal ultrasound; fetal therapy; delivery; vaginal delivery; operative vaginal delivery; cesarean section; adverse perinatal outcomes
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advances in Physiologically Based Pharmacokinetics submission deadline 20 Jun 2026 | 1 articles | Viewed by 1474 | Submission Open
Keywords: personalized medicine; precision dosing; mechanistic modeling and simulation; microphysiological systems; pharmacokinetics
(This special issue belongs to the Section Pharmacogenetics)
The Future of Personalized Orthodontics
edited by and Loredana Golovcencu
submission deadline 20 Jun 2026 | Viewed by 310 | Submission Open
Keywords: personalized orthodontics; clear aligner therapy; AI-driven orthodontics; digital orthodontic planning; skeletal anchorage systems; surgery-first approach; 3D imaging in orthodontics; customized biomechanics; interdisciplinary treatment in orthodontics; precision orthodontics
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Gynecological Oncology: Personalized Diagnosis and Therapy
edited by Stuart Rundle and Ali Kucukmetin
submission deadline 25 Jun 2026 | 4 articles | Viewed by 10973 | Submission Open
Keywords: gynaecologic oncology; surgical oncology; medical oncology; radiation oncology; clinical oncology; palliative medicine; diagnosis; translational research; stratification; patient selection; genomics
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine for Rheumatic Diseases
edited by Rossella De Angelis, and Emilio Filippucci
submission deadline 25 Jun 2026 | 5 articles | Viewed by 9131 | Submission Open
Keywords: chronic arthritis; rheumatoid arthritis; seronegative arthritis; crystal arthropathies; connective tissue diseases; autoimmunity; laboratory medicine; ultrasound; nailfold capillaroscopy; clinimetric tools
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Child and Adolescent Psychiatry: Latest Research, Prevention and Treatment
edited by
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1966 | Submission Open
Keywords: child and adolescent psychiatry; mental health; sleep disturbances; depression; anxiety; eating disorders
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Diagnosis and Treatment in Sports Medicine
edited by Maria Ruberto and
submission deadline 25 Jun 2026 | 2 articles | Viewed by 1447 | Submission Open
Keywords: personalized sports medicine; athlete-specific diagnostics; tailored treatment protocols; sports injury prevention; biomechanical analysis; digital health in athletics; wearable health technologies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Genetic Counseling and Genome Sequencing in Pediatrics
edited by Monika Lejman
submission deadline 25 Jun 2026 | 1 articles | Viewed by 955 | Submission Open
Keywords: pediatric disease; genome sequencing; genetic counseling; personalized medicine; genetic diagnostics
(This special issue belongs to the Section Omics/Informatics)
Personalized Approaches in Endocrine Surgical Innovation
edited by Leonardo Rossi
submission deadline 25 Jun 2026 | 1 articles | Viewed by 566 | Submission Open
Keywords: minimally invasive surgery; ablative treatments; robotic thyroidectomy; thyroid cancer; parathyroid disorders; adrenal tumors; active surveillance; medullary thyroid carcinoma; personalized endocrine care
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Dentistry and Oral Surgery
edited by Inês Francisco, and
submission deadline 25 Jun 2026 | Viewed by 249 | Submission Open
Keywords: precision medicine; dentistry; oral health; clinical research; personalized treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Novel Insights in Diagnostics and Personalized Therapeutics in Obstetrics and Gynecology submission deadline 28 Jun 2026 | 1 articles | Viewed by 925 | Submission Open
Keywords: pregnancy complications; adverse pregnancy outcomes; preeclampsia; preterm labor; gynecologic oncology; minimal invasive endoscopic surgery
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
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