Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Diagnosis and Treatment in Otorhinolaryngology
edited by Delia Hînganu and Marius Valeriu Hînganu
submission deadline 30 Apr 2025 | Viewed by 255 | Submission Open
Keywords: ENT surgery; multimodality imaging; prevention; voice formation; middle ear pathology; inner ear pathology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diabetic Foot: New Devices and AI for Clinical Diagnosis and Therapies in Personalized Medicine submission deadline 30 Apr 2025 | Viewed by 243 | Submission Open
Keywords: diabetic foot ulcers; diabetic foot infections; diabetic foot mortality; diabetic foot treatment therapy; artificial intelligence; devices; diagnosis; personalized therapies; sensors; artificial intelligence; big data; data mining; data science; deep learning; machine learning; bioimage recognition; bioinformatics; neural network; biosignals
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Neurooncology and Neurosurgery for the 21st Century, 2nd Edition
edited by and José Pedro Lavrador
submission deadline 30 Apr 2025 | Viewed by 212 | Submission Open
Keywords: neurooncology; brain tumour/tumour; precision; personalized; glioma; brain mapping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Complex Spine Surgery: The Road from Childhood to Adults and Future Directions
edited by Pawel Grabala, Michael A. Galgano and Jacob M. Buchowski
submission deadline 30 Apr 2025 | Viewed by 186 | Submission Open
Keywords: complex spine; scoliosis; kyphosis; spinal deformities; spinal tumor; spinal reconstruction; sagittal balance; coronal imbalance
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Translational Research and Novel Therapeutics in Cutaneous Melanoma
edited by Maja Tolušić Levak and Martina Mihalj
submission deadline 30 Apr 2025 | Viewed by 89 | Submission Open
Keywords: cutaneus melanoma; immunopathology of melanoma; biomarkers; novel treatments; early diagnosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Management in Degenerative and Traumatic Hand Surgery
edited by , Martin Lautenbach and
submission deadline 30 Apr 2025 | Viewed by 73 | Submission Open
Keywords: hand surgery; elbow surgery; rheumatoid diseases of the hand; degenerative changes of the hand; rheumatoid orthopedics; hand surgery; hand trauma surgery; small joint arthritis; arthrodesis of the hand; geriatric trauma surgery; robotic-assisted surgeries; personalized care; physical therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Diagnostics and Management of Respiratory System Diseases
edited by and Chao-Tien Hsu
submission deadline 30 Apr 2025 | Viewed by 66 | Submission Open
Keywords: elderly; geriatric respiratory diseases; cardiovascular disease; metabolic disease; cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Epidemiology, Biomarkers, Prevention and Therapy in Neonatal Infectious Diseases: From Empirical to Personalized Approach
edited by Vito Mondı̀, , Chryssoula Tzialla and
submission deadline 30 Apr 2025 | Viewed by 50 | Submission Open
Keywords: pharmacology in the newborn; new biomarkers in neonatal infections; epidemiology of neonatal infections; omics in neonatal infections; prevention of neonatal infections
(This special issue belongs to the Section Epidemiology)
Personalized Applications of Musculoskeletal Imaging
edited by Daniela Berritto and
submission deadline 30 Apr 2025 | Viewed by 42 | Submission Open
Keywords: musculoskeletal; artificial intelligence; ultra-high-frequency ultrasound; cone beam CT; low-field MRI  ; photoacoustic  ; advances
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Progress in Personalized Management of Cardiac Surgery
edited by Chiara Tessari and Augusto D'Onofrio
submission deadline 30 Apr 2025 | Viewed by 39 | Submission Open
Keywords: clinical and hemodynamic evaluation of heart valve bioprostheses and tissue engineering; clinical and hemodynamic evaluation of heart valve repair techniques; advanced heart failure and surgical treatment options; immunological evaluation in heart transplant patients; cardiovascular regenerative medicine; telemedicine and artificial intelligence application in cardiac surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in the Intensive Care Unit
edited by Carmen Orban and
submission deadline 10 May 2025 | Viewed by 326 | Submission Open
Keywords: critical care; phenotypes in the intensive care unit; personalized medicine; patient-centered management; organ dysfunction; organ support; advanced monitoring; diagnostics
(This special issue belongs to the Section Personalized Critical Care)
New Approaches in Pharmacogenomics
edited by
submission deadline 10 May 2025 | Viewed by 193 | Submission Open
Keywords: personalized medicine; supporting tools/software for personalized medicine; pharmacogenomic test; pharmacogenomic education; drug response; genomic biomarker; functional genomics; healthcare system
(This special issue belongs to the Section Pharmacogenetics)
Novel and Personalized Treatment Concepts in Gynecologic Cancer—2nd Edition
edited by and
submission deadline 10 May 2025 | Viewed by 76 | Submission Open
Keywords: ovarian cancer; endometrial cancer; vulvar cancer; cervical cancer; homologous recombination; targeted therapy; DNA damage repair; biomarkers; imaging; individualized treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Personalized Therapy in Chronic Upper Aerodigestive Tract Disorders
edited by Maria Raffaella Marchese
submission deadline 15 May 2025 | 1 articles | Viewed by 1452 | Submission Open
Keywords: upper aerodigestive tract; swallowing; voice; rhinitis; sinonasal diseases; dysphonia; tonsillitis; peritonsillar abscess; OSAS; laryngopharyngeal reflux
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Current Trends in Cataract Surgery
edited by Romina Fasciani and Paola Sasso
submission deadline 15 May 2025 | Viewed by 242 | Submission Open
Keywords: refractive cataract surgery; visual quality; dry eye; side effects; advanced technology intraocular lenses; AMD IOLs
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Trends and Challenges in Digital Dentistry
edited by and Flares Baratto-Filho
submission deadline 15 May 2025 | Viewed by 87 | Submission Open
Keywords: dental research; tomography; radiograph; artificial inteligence; machine learning; digital dentistry
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Tailoring Treatment with Biomarkers: Advancements in Heart Failure Management submission deadline 16 May 2025 | 2 articles | Viewed by 2661 | Submission Open
Keywords: biomarkers; heart failure; precision cardiology; risk prediction; outcomes; treatment
(This special issue belongs to the Section Disease Biomarker)
Diabetes Mellitus: Current Research and Future Perspectives 2nd Edition
edited by
submission deadline 20 May 2025 | 2 articles | Viewed by 1593 | Submission Open
Keywords: diabetes treatment; drug metabolism; disease complications; polymorphisms; epigenetics; metabolomics; proteomics
(This special issue belongs to the Section Mechanisms of Diseases)
Breast Cancer: Current Trends and Future Challenges in Evaluation and Treatment
edited by Stefano Spinaci and Giulia Ferrarazzo
submission deadline 20 May 2025 | 1 articles | Viewed by 739 | Submission Open
Keywords: breast cancer; breast surgery; conservative surgery; robotic breast techniques; male breast cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Therapeutics and Drug Development of Liver Disease submission deadline 20 May 2025 | Viewed by 36 | Submission Open
Keywords: precision medicine; hepatocellular carcinoma (hcc); non-alcoholic fatty liver disease (nafld); metabolic dysfunction-associated steatotic liver disease (masld); liver fibrosis; biomarkers; targeted therapy; drug development; pharmacogenomics; immunotherapy; molecular pathways; genomic profiling; personalized treatment; translational research; clinical trials; novel therapeutics; liver disease management; drug delivery systems
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Sex and Gender-Related Issues in the Era of Personalized Medicine
edited by , Anna Maria Moretti and Biagio Moretti
submission deadline 22 May 2025 | 7 articles | Viewed by 6969 | Submission Open
Keywords: gender; sex differences; sex factors; personalized medicine; cardiovascular disease; hypertension; obesity; diabetes; psychiatry and psychology; public health and epidemiology; women’ s health; sex; osteoporosis; osteoarthritis; musculoskeletal diseases
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
Innovations in Personalized Diagnosis and Treatment for Cystic Fibrosis
edited by
submission deadline 22 May 2025 | Viewed by 64 | Submission Open
Keywords: cystic fibrosis; CFTR mutations; modulators; biomarkers; treatment strategies; theratyping; genotype– phenotype correlation; pharmacogenomics; gene therapy; disease modeling; precision medicine; personalized diagnostics and therapies
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Emergency Medicine: Clinical Advances and Challenges in Diagnosis and Treatment, 2nd Edition submission deadline 25 May 2025 | 9 articles | Viewed by 10023 | Submission Open
Keywords: shock and resuscitation; sepsis; learning; critical patient approach; medical education; challenging diagnosis; treatment advances; use of simulation in medical training; emergency department digitalization; interesting cases in emergency medicine; diagnostic and therapeutic protocols in emergency medicine
(This special issue belongs to the Section Personalized Critical Care)
The Gut Microbiome as a Target for the Treatment of Inflammatory Bowel Diseases
edited by and
submission deadline 25 May 2025 | 1 articles | Viewed by 2624 | Submission Open
Keywords: inflammatory bowel diseases (IBD); gut microbiome; microbial dysbiosis; Crohn's disease; ulcerative colitis; microbiota; microbiome– host interactions; immune response; microbial metabolites; fecal microbiota transplantation (FMT); probiotics; prebiotics; postbiotics; precision medicine; personalized therapy; microbial biomarkers; microbiome-based interventions; microbiome modulation; mucosal healing; gut– brain axis; microbiome analysis techniques; clinical trials; translational research; microbial engineering; therapeutic targets; metabolomics
(This special issue belongs to the Section Disease Biomarker)
Clinical Advances in Dermatology: Pathophysiology, Diagnosis and Treatment
edited by and Manuel Galán-Gutiérrez
submission deadline 25 May 2025 | 2 articles | Viewed by 2277 | Submission Open
Keywords: psoriasis; atopic dermatitis; laser therapy; urticaria; alopecia areata; treatment; biological treatment; JAK (Janus Kinase) inhibitors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine for Autism Spectrum Disorder
edited by
submission deadline 25 May 2025 | Viewed by 456 | Submission Open
Keywords: autism spectrum disorder; comorbidity; personalized medicine; environmental factors; diagnosis; classification; treatment; management
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Pediatric Neurology: Current Trends, Rehabilitation and Future Challenges, 2nd Edition
edited by
submission deadline 25 May 2025 | Viewed by 289 | Submission Open
Keywords: neurodevelopmental disorders; cerebral palsy; autism; assessment; sleep
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Cardiovascular Disease
edited by
submission deadline 25 May 2025 | Viewed by 257 | Submission Open
Keywords: cardiovascular disease; personalized medicine  ; genomics; risk prediction  ; precision therapy  ; AI; telediagnostics  ; telemedicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Biomarkers and Personalized Diagnosis in Neurodegenerative Disease
edited by Edoardo Gioele Spinelli
submission deadline 25 May 2025 | Viewed by 230 | Submission Open
Keywords: Alzheimer’ s disease; dementia; amyotrophic lateral sclerosis; Parkinson’ s disease; neurodegeneration; neuroimaging; MRI; biomarkers; artificial intelligence; machine learning
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Urological Cancer: Clinical Advances in Personalized Therapy
edited by and Marco Paciotti
submission deadline 25 May 2025 | Viewed by 173 | Submission Open
Keywords: minimally invasive surgery; robot-assisted surgery; immunotherapy; prostate cancer; renal cancer; urothelial cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Diagnostic and Interventional Radiology: Opportunities and Challenges of Advanced Imaging Techniques
edited by Leona S. Alizadeh and Boris Bodelle
submission deadline 25 May 2025 | Viewed by 61 | Submission Open
Keywords: advanced imaging techniques; diagnostic radiology; interventional radiology; personalized medicine; precision diagnosis; minimally invasive procedures; image-guided therapy; artificial intelligence in radiology; cardiovascular imaging; oncology imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cancer Immunology: New Advances in Personalized Therapies
edited by John Victor Napoleon
submission deadline 25 May 2025 | Viewed by 53 | Submission Open
Keywords: personalized therapy; immune system modulation; drugs and pharmaceutics; checkpoint inhibitor therapy; cancer immunotherapy; targeted drug delivery; tumor microenvironment; treatment resistance; combination therapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine of Obesity and Metabolic Disorders
edited by , and Cătălina Poiană
submission deadline 25 May 2025 | Viewed by 38 | Submission Open
Keywords: obesity; childhood obesity; metabolic disorders; leptin; adipogenesis; adipokines; dietary intake; physical activity; behavior; obesity-related diseases
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Innovations in Cancer Immunology: Personalized Therapeutic Approaches
edited by
submission deadline 25 May 2025 | Viewed by 35 | Submission Open
Keywords: cancer immunology; personalized therapies; immunotherapy; CAR-T cell therapy; tumor microenvironment; biomarkers; patient selection; treatment resistance; combination therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Machine Learning in Epidemiology
edited by Xingyu Zhang and
submission deadline 30 May 2025 | Viewed by 43 | Submission Open
Keywords: artificial intelligence; machine learning; epidemiology; predictive analytics; health data; public health; precision medicine; disease surveillance; big data analytics
(This special issue belongs to the Section Epidemiology)
New Insights into Personalized Medicine for Cardiac Surgery
edited by Sharaf Eldin Shehada and Anja Osswald
submission deadline 30 May 2025 | Viewed by 24 | Submission Open
Keywords: cardiovascular disease; patient-centered care; personalized medicine; interdisciplinary approaches; artificial intelligence; prognostic tools; minimally invasive surgery; robotic surgery; bioengineering; cardiovascular genomics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Selected Papers From the pHealth 2024 Conference, Rende, Italy, 27–29 May 2024
edited by , and Pierangelo Veltri
submission deadline 30 May 2025 | Submission Open
Keywords: 5P medicine; transformed health ecosystems; systems integration and interoperability; knowledge representation and management
(This special issue belongs to the Section Omics/Informatics)
Cardiology and Vascular Health: Pathophysiology, Therapeutics and Epidemiology submission deadline 31 May 2025 | 5 articles | Viewed by 9534 | Submission Open
Keywords: cardiovascular disease; peripheral arterial disease; coronary heart disease; heart failure; cerebrovascular diesease; diabetes mellitus; dyslipidemia; arterial hypertension; arterial stiffness; endothelial dysfunction
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Advances in Metabolic Diseases Diagnostics and Treatment: From Basic Research to Clinical Practice submission deadline 31 May 2025 | 1 articles | Viewed by 1545 | Submission Open
Keywords: metabolic disease; inherited metabolic disease; mitochondrial metabolism; metabolomics; multi-omics; biomarkers
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Challenges and Opportunities in Personalized Management of Bone and Joint Infections submission deadline 31 May 2025 | 1 articles | Viewed by 1304 | Submission Open
Keywords: bone and joint infections; prosthetic joint infection; arthroplasty infection; definition of prosthetic joint infection; prosthetic joint infection prevention; diagnosis of prosthetic joint infection; prosthetic joint infection management; antimicrobial therapy of prosthetic joint infection; diagnostics and management of septic arthritis in native joints; future research directions for improved patient outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Urologic Oncology
edited by Orsolya Martha and Calin Chibelean
submission deadline 31 May 2025 | Viewed by 350 | Submission Open
Keywords: urodynamics; urooncology; reconstruction; LUTS; functional urology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diagnostics and Therapeutics in Ophthalmology—2nd Edition
edited by
submission deadline 31 May 2025 | Viewed by 52 | Submission Open
Keywords: ophthalmology; retina; myopia; glaucoma; cataract; clinical studies; systematic reviews; meta-analyses
(This special issue belongs to the Section Evidence Based Medicine)
Interventional Cardiology: Advances in Personalized Treatment and Management
edited by
submission deadline 31 May 2025 | Viewed by 47 | Submission Open
Keywords: interventional cardiology; ischaemic disease; cardiovascular diseases; coronary artery disease; percutaneous coronary intervention; structural heart disease; transcatheter; minimally invasive; intravascular imaging; vascular access; pharmacological treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Management in Chronic Obstructive Pulmonary Disease (COPD)
edited by Paolo Ruggeri
submission deadline 31 May 2025 | Viewed by 22 | Submission Open
Keywords: COPD; lung function; comorbidities; cardiopulmonary risk; exacerbation; inhalation therapy; early diagnosis; phenotyping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Ophthalmology: Diagnosis, Prevention, and Treatment
edited by Antonio Di Zazzo and
submission deadline 31 May 2025 | Viewed by 3 | Submission Open
Keywords: ocular surface; dry eye disease; scleral lenses; corneal disease; keratoconus
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Orthopedic Surgery and Sports Medicine: Trends, Clinical Outcomes and Rehabilitation
edited by Robert Prill and
submission deadline 10 Jun 2025 | Viewed by 63 | Submission Open
Keywords: knee surgery; sports traumatology; arthroscopy; rehabilitation; physiotherapy; research standards; reliability; validity; total knee arthroplasty
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Omics Technologies for Precision Medicine in Kidney Diseases
edited by
submission deadline 20 Jun 2025 | Viewed by 28 | Submission Open
Keywords: precision medicine; omics technologies; kidney diseases; genomics; proteomics; metabolomics; transcriptomics; biomarkers; molecular pathophysiology; data integration
(This special issue belongs to the Section Omics/Informatics)
Personalized Diagnostics and Therapy for Cardiovascular Diseases
edited by Katharina Lechner and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 857 | Submission Open
Keywords: predictive; personalized; preventive; and participatory (4P) medicine; cardiovascular prevention; hypertension; lipids and lipoproteins; telemedicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Minimally Invasive Thoracic Surgery: Risk Assessment and Personalized Perioperative Management
edited by and Vannucci Jacopo
submission deadline 31 Jul 2025 | Viewed by 45 | Submission Open
Keywords: VATS; ERAS; sublobar resection; risk assessment; minimally invasive thoracic surgery
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
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