The Spinal Neuromodulation of Motor and Autonomic Functions

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 1756

Special Issue Editors


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Guest Editor
Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia
Interests: spinal cord; motor physiology; autonomic systems; rehabilitation

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Guest Editor
1. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia
2. Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, KY, USA
Interests: spinal cord; locomotion; central pattern generator; electrical stimulation

Special Issue Information

Dear Colleagues,

The spinal cord is pivotal to the regulation of vital functions.

It is well established that that spinal locomotor-related neuronal circuitry in humans can be neuromodulated by electrical spinal cord stimulation to regain sensorimotor function after complete paralysis due to spinal cord injury. The electrical, electromagnetic, or pharmacological stimulation of the spinal cord, addressed to the spinal locomotor networks, also affects the autonomic nerve system both directly and indirectly through the movements caused. The mechanisms of this integration remain not fully understood.

Scattered data have now been accumulated on the possible mechanisms of action centered around the stimulation of the spinal cord in relation to breathing, peripheral and cerebral blood circulation, cardiovascular, excretory, and digestive systems. The Special Issue will focus on the fundamental regulation mechanisms of motor and autonomic functions by neuromodulating the spinal cord, as well as the development of new approaches for the treatment and rehabilitation of individuals associated with motor pathology of different genesis.

Dr. Tatiana Moshonkina
Prof. Dr. Yury P. Gerasimenko
Guest Editors

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Keywords

  • spinal cord
  • neuromodulation
  • motor control
  • autonomic systems
  • rehabilitation

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Published Papers (1 paper)

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6 pages, 228 KiB  
Opinion
Using a Pulse Protocol to Fix the Individual Dosage of Transcranial and Transspinal Direct Current Electrical Stimulation
by Evgeny Blagovechtchenski, Svetlana Kostromina and Alla Shaboltas
Life 2023, 13(6), 1376; https://doi.org/10.3390/life13061376 - 12 Jun 2023
Viewed by 1246
Abstract
The non-invasive current stimulation protocol differs significantly between the brain and spinal cord, such that when comparing the two, there is a clear predominance of protocols using transcranial direct current stimulation (tDCS) for the brain and of protocols using pulsed stimulation for the [...] Read more.
The non-invasive current stimulation protocol differs significantly between the brain and spinal cord, such that when comparing the two, there is a clear predominance of protocols using transcranial direct current stimulation (tDCS) for the brain and of protocols using pulsed stimulation for the spinal cord (psSC). These protocols differ in their effects on the central nervous system and in such important parameters as stimulation intensity. In most cases, tDCS has a fixed amplitude for all subjects/patients, while psSC is usually chosen on a case-by-case basis, according to the thresholds of muscle responses. In our opinion, it is possible to use the experience of identifying thresholds during psSC to adjust the dose of the direct current for transcranial and transspinal electrical stimulation, an approach that may provide more homogeneous tDCS data. Full article
(This article belongs to the Special Issue The Spinal Neuromodulation of Motor and Autonomic Functions)
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