State-of-the-Art Diagnosis and Treatment of Cerebral Veins and Dural Sinuses Thrombosis
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 15 December 2024 | Viewed by 109
Special Issue Editors
2. Head of the Centre for Advanced Research titled: “Cognitive Research in Neuropsychiatric Pathology” (Neuro-Psy-Cog), First Division of Neurology, Department of Neurosciences, “Victor Babes” University of Medicine and Pharmacy, 156 L. Rebreanu Ave., 300723 Timisoara, Romania
3. Head of the First Dept. of Neurology, “Pius Branzeu” Clinical Emergency County Hospital, no.156, L. Rebreanu Ave., 300723 Timisoara, Romania
Interests: cerebral vein and dural sinus thrombosis; ischemic stroke and extra and transcranial Doppler sonography (large-artery diseases and small-artery diseases); vascular aphasias; vascular cognitive impairment; neuro-ophthalmology and color Doppler imaging of orbital vessels; Parkinson’s disease
Special Issues, Collections and Topics in MDPI journals
Interests: stroke; cerebral venous thrombosis; neuro-ophthalmology and color Doppler imaging of cerebral and orbital vessels; noninvasive explorations of large-artery diseases/extra and transcranial Doppler sonography
Special Issues, Collections and Topics in MDPI journals
2. RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania
Interests: cerebrovascular diseases; neurodegenerative diseases; traumatic brain injury; brain protection and recovery; neurorehabilitation; neuroimmunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cerebral vein and intracranial dural sinus thrombosis (CVT) is a relatively uncommon disease in the general population. At least one risk factor can be identified in 85% of CVT cases. Searching for a thrombophilic state should be realized for patients with CVT who present a high pretest probability of severe thrombophilia. Two pathophysiological mechanisms determine their highly variable clinical spectrum: augmentation of venular and capillary pressure, and the diminution of cerebrospinal fluid absorption. The clinical spectrum of CVT is usually non-specific. Four major syndromes have been observed: isolated intracranial hypertension, seizures, focal neurological signs and encephalopathy.
Non-enhanced computer tomography (NECT) of the head is the most frequently performed imaging technique in the emergency department. CVT diagnosis is confirmed with CT venography (CTV), directly detecting the venous clot as a filling defect, or magnetic resonance imaging (MRI) /MR venography (MR-V), which also realizes a better description of parenchymal abnormalities. Acute-phase therapy for CVT focuses on anticoagulation, the management of seizures, increased intracranial pressure and the prevention of cerebral herniation. The majority of patients have a complete or partial recovery; however, they have an increased incidence of venous thromboembolism. Clinical and imaging follow-ups 3–6 months after diagnosis are recommended to assess for recanalization.
This Special Issue of Life (IF = 3.2) includes, but is not limited to, the following topics: the anatomy of dural sinuses and encephalic veins; the epidemiology, risk factors and pathophysiology of CVT; and the clinical presentation, laboratory testing (including thrombophilia testing) and imaging of CVT. The management of CVT represents another important aspect devoted to acute phase therapy, management after the acute phase and the prognosis of CVT patients.
We are pleased to invite you to submit a manuscript covering experimental and clinical research, as well as systematic reviews and meta-analyses.
The accepted papers will be published continuously in the journal (as soon as accepted) and listed together on the Special Issue’s website.
Prof. Dr. Dragos Catalin Jianu
Dr. Jean Claude Sadik
Prof. Dr. Dafin Fior Muresanu
Guest Editors
Manuscript Submission Information
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Keywords
- cerebral vein and intracranial dural sinus thrombosis (CVT)
- thrombophilia
- isolated intracranial hypertension
- non-enhanced computer tomography (NECT) of the head
- computer tomography venography (CTV)
- magnetic resonance imaging (MRI) of the head
- magnetic resonance venography (MRV)
- anticoagulation
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