Lumpy Skin Disease: Epidemiology, Phylogeny and Transmission

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 1907

Special Issue Editor


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Guest Editor
Federal Centre for Animal Health ARRIAH, 600901 Vladimir, Russia
Interests: capripoxvirus; phylogeny; recombination; epidemiology; transmission

Special Issue Information

Dear Colleagues,

Lumpy skin disease (LSD) is still on the rise and continues to challenge research communities worldwide. A great body of data has been published since the first incursions of LSD into Turkey, Balkans, and Russia in 2015–2017, followed by the emergence of recombinant vaccine-like strains formed by an attenuated Neethling vaccine strain and Kenyan KSGP strain. The novel strains have now spread to China, Vietnam, and Thailand; however, in India, another strain is circulating, with no feasible explanations yet provided for why. The plethora of genetic lineages and their novel properties demonstrated up to now clearly highlight the knowledge gaps that concern i) LSD epidemiology in Eurasia with a focus on differences across latitudes, regional features, and climate; ii) molecular evolution in the context of the expansion of recombinant vaccine-like strains; iii) transmission by clinically and subclinically ill animals infected by classical and recombinant isolates; and iv) diagnostics for efficient and reliable diagnosis.  

As a guest editor of this Special Issue, I, Alexander Sprygin, invite you to submit research and review articles as well as short communications that contribute to the existing knowledge gaps and to the better understanding of LSD epidemiology, molecular evolution, and diagnostics.

In this regard, research areas may include (but are not limited to) the following:

  • Field studies reporting epidemiological findings
  • Sequencing and NGS studies
  • Description of novel recombinant vaccine-like strains
  • Description of clinical signs and post-mortem findings observed in the field and under experimental conditions
  • Experimental findings on transmission
  • Development of diagnostic assays

I look forward to receiving your contributions

Dr. Alexander Sprygin
Guest Editor

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Published Papers (1 paper)

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8 pages, 2547 KiB  
Brief Report
A Study of the Susceptibility of Laboratory Animals to the Lumpy Skin Disease Virus
by Elena Yurievna Pivova, Mikhail Evgenievich Vlasov, Timofey Aleksandrovich Sevskikh, Olga Sergeevna Povolyaeva and Sergey Petrovich Zhivoderov
Life 2023, 13(7), 1489; https://doi.org/10.3390/life13071489 - 30 Jun 2023
Cited by 1 | Viewed by 1445
Abstract
This article presents the results of a study on the susceptibility of laboratory animals to the lumpy skin disease virus (LSDV). Mice weighing 15–20 g, hamsters weighing 40–60 g, guinea pigs weighing 600–1200 g, and rabbits weighing 2.5–3 kg were used in this [...] Read more.
This article presents the results of a study on the susceptibility of laboratory animals to the lumpy skin disease virus (LSDV). Mice weighing 15–20 g, hamsters weighing 40–60 g, guinea pigs weighing 600–1200 g, and rabbits weighing 2.5–3 kg were used in this study. Nodules were observed on the skin of rabbits and hamsters at the sites of inoculation. The virus was isolated from the affected skin areas in cell culture and examined using real-time PCR, indicating its tropism for animal skin. The production of anticapripoxvirus antibodies was detected using the neutralization reaction, starting from 10 days after infection in mice, 27 days in rabbits, and 14 days in hamsters. Some laboratory animals exhibited multiple skin nodules. This indicates that these animal species may play a role in maintaining the epizootic process. Full article
(This article belongs to the Special Issue Lumpy Skin Disease: Epidemiology, Phylogeny and Transmission)
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