Advances in Circadian Clock Regulation of Reproduction and Metabolism
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2615
Special Issue Editors
Interests: circadian clock; circadian rhythm; circadian clock gene; reproduction; metabolism; testis; ovary; liver; steroid hormones synthesis; ovarian follicular development; endoplasmic reticulum stress; lipid metabolism; glucose metabolism; glycogen synthesis
Special Issue Information
Dear Colleagues,
Circadian clocks are cell-autonomous oscillators that provide organisms with an internal mechanism to maintain coherent order in a rhythmic environment. Circadian clocks drive numerous circadian rhythmic changes in physiological functions and behaviors, including sleep-wake cycles, feeding behaviors, reproduction, and metabolism. In mammals, the central circadian pacemaker controlling circadian rhythms resides in the suprachiasmatic nuclei (SCN) of the hypothalamus. Circadian clocks also exist in many peripheral tissues, including the liver, heart, kidney, white adipose tissue, testis, ovary, and uterus. Both the SCN and peripheral circadian clocks share a molecular mechanism comprising a subset of circadian clock genes and their protein products. The SCN orchestrates peripheral circadian clocks via humoral and neuronal pathways, thereby maintaining mammalian reproductive and metabolic homeostasis. Therefore, Circadian disturbances (circadian clock genes mutation, shift work, jet lag) are often associated with metabolic diseases and reproductive disorders.
This Special Issue of Life, entitled “Advances in Circadian Clock Regulation of Metabolism and Reproduction”, will comprise a selection of research papers and reviews covering mammalian circadian clock regulation of metabolism and reproduction. Contributions on the relationship between the circadian clock, reproduction, and metabolism, as well as the circadian disruption for health, will be welcome. Studies on chronotherapy modulating circadian rhythms for the cure and prevention of metabolic diseases and reproductive disorders will also be considered.
Dr. Huatao Chen
Dr. Hsu-Wen Chao
Guest Editors
Manuscript Submission Information
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Keywords
- Circadian clock
- Circadian rhythms
- Circadian disruptions
- Reproduction
- Metabolism
- Ovary
- Testis
- Uterus
- Liver
- White adipose tissue
- Embryo implantation
- Energy metabolism
- Lipid
- Glucose
- Glycogen
- Protein
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