Cancer Genomics and Transcriptomics: Uncovering New Frontiers in Tumor Biology

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 31

Special Issue Editors


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Guest Editor
Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece
Interests: biochemistry; molecular biology; genomics
Special Issues, Collections and Topics in MDPI journals

E-Mail
Guest Editor
Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece
Interests: clinical biochemistry; genomics; molecular biology

Special Issue Information

Dear Colleagues,

Cancer genomics and transcriptomics have revolutionized our understanding of tumor biology, revealing the intricate molecular landscapes that drive cancer progression and response to therapy. This Special Issue, titled "Cancer Genomics and Transcriptomics: Uncovering New Frontiers in Tumor Biology", will showcase the latest advancements and emerging trends in these fields, providing a comprehensive overview of how genomic and transcriptomic analyses are reshaping cancer research and treatment. We will explore cutting-edge studies that leverage high-throughput sequencing technologies to dissect the genetic and transcriptomic alterations underpinning various cancer types. Key topics include understanding the functional roles of established oncogenes and tumor suppressor genes, the impacts of non-coding RNAs in cancer, and the influence of somatic mutations on tumor heterogeneity and drug resistance. Furthermore, we will highlight integrative strategies that merge genomics and transcriptomics with other omics data to unravel the complexities of tumor biology and enhance patient stratification. This Special Issue will also address the challenges and opportunities associated with translating genomic and transcriptomic discoveries into clinical practice. By bringing together contributions from leading researchers in the field, this Special Issue will provide insights into the latest methodologies, foster collaborative efforts, and stimulate future research directions. Ultimately, our goal is to advance the development of personalized cancer therapies and enhance our understanding of the molecular mechanisms driving cancer, paving the way for more effective and targeted treatment strategies.

Dr. Panagiotis Adamopoulos
Dr. Panagiotis Tsiakanikas
Guest Editors

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Keywords

  • transcriptomic profiling
  • tumor heterogeneity
  • integrative omics
  • non-coding RNAs
  • oncogenes

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