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Life
Special Issues
Early Diagnosis and Management of Gynecological Malignancies
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Early Diagnosis and Management of Gynecological Malignancies

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (15 September 2024) | Viewed by 1866

Special Issue Editor

Dr. Vasileios Pergialiotis

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Guest Editor
First Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, 11527 Athens, Greece
Interests: gynecological malignancies

Special Issue Information

Dear Colleagues,

Gynecological malignancies, including ovarian, cervical, uterine, and vulvar cancers, are a significant health concern worldwide. Early diagnosis and management of gynecological cancer play a crucial role in improving patient outcomes and reducing morbidity and mortality associated with these cancers. In recent years, there have been significant advances in understanding the risk factors, screening methods, diagnostic tools, and treatment options for gynecological malignancies, which have contributed to improving the rates of earlier detection and creating management strategies. The main goal of early diagnosis of gynecological malignancies is to identify the disease at an early stage when it is most treatable, thus improving patient survival rates and overall prognosis.

In this Special Issue, we would like to welcome contributions that will include original research articles (clinical and preclinical), reviews, or shorter perspective articles that emphasize the benefits and pitfalls of adjuvant and neoadjuvant therapies in gynecological cancer patients. Topics including, but not limited to, articles referring to the early detection of endometrial cancer pathology, pre-invasive and invasive forms of cervical cancer, pre-operative assessment of suspicious ovarian masses, and early diagnosis of vulvar cancer with an emphasis on their impact on survival outcomes and patient-reported outcomes, including quality of life, are welcome in this Special Issue.

We hope that leading experts will share their perspectives on the clinical management and outcomes of patients with gynecological cancer, contributing to our current knowledge with novel evidence that will provide the groundwork for further research.

Dr. Vasileios Pergialiotis
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ovarian cancer
  • cervical cancer
  • uterine cancer
  • vulvar cancer
  • early diagnosis
  • morbidity and mortality
  • prognosis

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Published Papers (1 paper)

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Review

17 pages, 265 KiB  
Review
Screening for Breast Cancer: A Comparative Review of Guidelines
by Laskarina Katsika, Eirini Boureka, Ioannis Kalogiannidis, Ioannis Tsakiridis, Ilias Tirodimos, Konstantinos Lallas, Zoi Tsimtsiou and Themistoklis Dagklis
Life 2024, 14(6), 777; https://doi.org/10.3390/life14060777 - 19 Jun 2024
Cited by 1 | Viewed by 1594
Abstract
Breast cancer is the most common malignancy diagnosed in the female population worldwide and the leading cause of death among perimenopausal women. Screening is essential, since earlier detection in combination with improvements in breast cancer treatment can reduce the associated mortality. The aim [...] Read more.
Breast cancer is the most common malignancy diagnosed in the female population worldwide and the leading cause of death among perimenopausal women. Screening is essential, since earlier detection in combination with improvements in breast cancer treatment can reduce the associated mortality. The aim of this study was to review and compare the recommendations from published guidelines on breast cancer screening. A total of 14 guidelines on breast cancer screening issued between 2014 and 2022 were identified. A descriptive review of relevant guidelines by the World Health Organization (WHO), the U.S. Preventive Services Task Force (USPSTF), the American Cancer Society (ACS), the National Comprehensive Cancer Network (NCCN), the American College of Obstetricians and Gynecologists (ACOG), the American Society of Breast Surgeons (ASBrS), the American College of Radiology (ACR), the Task Force on Preventive Health Care (CTFPHC), the European Commission Initiative on Breast Cancer (ECIBC), the European Society for Medical Oncology (ESMO), the Royal Australian College of General Practitioners (RACGP) and the Japanese Journal of Clinical Oncology (JJCO) for women both at average and high-risk was carried out. There is a consensus among all the reviewed guidelines that mammography is the gold standard screening modality for average-risk women. For this risk group, most of the guidelines suggest annual or biennial mammographic screening at 40–74 years, while screening should particularly focus at 50–69 years. Most of the guidelines suggest that the age limit to stop screening should be determined based on the women’s health status and life expectancy. For women at high-risk, most guidelines recommend the use of annual mammography or magnetic resonance imaging, while the starting age should be earlier than the average-risk group, depending on the risk factor. There is discrepancy among the recommendations regarding the age at onset of screening in the various high-risk categories. The development of consistent international practice protocols for the most appropriate breast cancer screening programs seems of major importance to reduce mortality rates and safely guide everyday clinical practice. Full article
(This article belongs to the Special Issue Early Diagnosis and Management of Gynecological Malignancies)
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