Mammalian Gametogenesis, Fertilization and Early Embryogenesis: 2nd Edition
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 737
Special Issue Editor
Interests: mammalian reproduction; epigenetics; cell–cell membrane interaction; genetic mutation; human disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mammals produce offspring through sexual reproduction. Thus, mammalian reproduction is vital for animal evolution, species existence, population growth, and animal health. The process of producing life includes gametogenesis, fertilization, embryogenesis, and post-delivery care. Mammalian gametogenesis is a highly orchestrated process that generates genetically and epigenetically unique gametes. Mammalian fertilization is the union of a sperm and an egg in a species-specific manner that forms a single-cell embryo called a zygote. The zygote, remarkably, reprograms the gamete-specific genome and epigenome to begin embryogenesis and the creation of a new organism.
It is well known that aberrant human reproduction can lead to infertility, birth defects, and genetic diseases. Although different mammalian species employ diverse strategies to deliver sperm to the egg, molecular mechanisms are largely conserved among mammals, including humans. Therefore, basic research into mammalian animal models may advance translational research in human reproductive medicine to improve human well-being.
The emergence of new technology and tools has recently significantly promoted our understanding of mammalian reproduction at the molecular, cellular, genetic, epigenetic, and genomic levels. It is of great interest to promptly broadcast fascinating discoveries and hypotheses to the scientific community and healthcare professionals. For this Special Issue, we invite scientists and clinicians to contribute original research articles, clinical studies, reviews, and perspectives that underscore novel findings in the areas of spermatogenesis, oogenesis, sperm–egg interactions, and zygotic activation. We envisage that this collection will further basic and translational research in mammalian reproduction.
Prof. Dr. Guo-Zhang Zhu
Guest Editor
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Keywords
- mammalian reproduction
- mammalian gametogenesis
- mammalian fertilization
- zygote
- embryogenesis
- spermatogenesis
- oogenesis
- sperm–egg interaction
- zygotic activation
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Related Special Issue
- Mammalian Gametogenesis, Fertilization and Early Embryogenesis in Life (3 articles)
