Primary Prevention of Cardiovascular Disease: Novel Mechanisms and Risk Factors

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Epidemiology".

Deadline for manuscript submissions: closed (30 May 2024) | Viewed by 1496

Special Issue Editor


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Guest Editor
1. Department of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 38221 Trikala, Greece
2. Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Athens, Greece
3. Faculty of Health, University of Canberra, Canberra, Australia
Interests: CVD epidemiology; nutrition; public health
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Special Issue Information

Dear Colleagues,

One out of two NCD-related deaths are related to CVD, accounting for 17.9 million people in 2018 alone. This rate is expected to increase five-fold by 2030. In Europe, age-standardized CVD mortality rates present a promising decline in many countries. However, from a public health perspective, the fact that the absolute number of CVD deaths remains high (principally in low/middle-income countries) and the fact that CVD remains the most common cause of death within the region suggest that CVD prevention still requires more attention. CVD also remains at the top of the morbidity ranking; in 2017, there were 19.9 million new cases of CVD in the 54 European Society of Cardiology member countries, with a small decline in the age-standardized incidence of CVD over the last 27 years. Major risk factors on the pathogenesis and precipitation of CVD include many cardiometabolic disorders from hypertension and dyslipidaemia to obesity and diabetes, while upcoming factors such as Lp(a), prediabetes, and liver fibrosis are highly discussed as well. Nevertheless, the connection of CVD with non-CVD conditions is another highly discussed pathophysicological route. For this, particular emphasis has been given to the role of psycho-social and cognition-related determinants, such as social isolation, chronic life stress, anxiety, hostility, depression, dementia, and others. This Special Issues aims to explore advances in the early prevention and risk assessment of heart disease with a specific focus on novel markers.

Dr. Matina Kouvari
Guest Editor

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Keywords

  • heart disease
  • coronary artery disease
  • risk factors
  • emerging factors
  • primary prevention

Published Papers (2 papers)

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Research

15 pages, 288 KiB  
Article
Effect of Crushed Flaxseed Consumption on Cardiovascular Risk Indicators in Menopausal Women
by Petra Lenártová, Martina Gažarová, Jana Kopčeková and Jana Mrázová
Life 2024, 14(7), 849; https://doi.org/10.3390/life14070849 - 5 Jul 2024
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Abstract
Flaxseed is known for its numerous health benefits and is often used in the prevention and treatment of civilizational diseases. This study aimed to evaluate the impact of consuming crushed flaxseed on cardiovascular risk in 51 menopausal women. The intervention lasted for 8 [...] Read more.
Flaxseed is known for its numerous health benefits and is often used in the prevention and treatment of civilizational diseases. This study aimed to evaluate the impact of consuming crushed flaxseed on cardiovascular risk in 51 menopausal women. The intervention lasted for 8 weeks, during which participants received a daily dose of 40 g of crushed flaxseed from two varieties with differing lignan contents. Participants were divided into three subgroups based on the variety of flaxseed consumed: (1) high-lignan group (HL), (2) low-lignan group (LL), and (3) control group (no flaxseed consumption). Biochemical blood parameters were measured using a BiOLis 24i Premium automatic analyzer. Body composition was assessed using an InBody 720 device. In the lipid profile, we observed a significant increase in total cholesterol (T-C) and high-density lipoprotein cholesterol (HDL-C) levels, along with a significant decrease in low-density lipoprotein cholesterol (LDL-C) levels in both the HL and LL groups. Triglyceride (TG) levels exhibited no significant change, whereas high-sensitivity C-reactive protein (hs-CRP) levels were significantly reduced in both the HL (p < 0.01) and LL (p < 0.01) groups. Visceral fat area (VFA) and percent body fat (PBF) showed a slight decreasing trend in the HL group, whereas in the LL group, VFA showed a slight increase. Body mass index (BMI) remained stable across all groups. These findings suggest that for the modulation of cardiovascular disease (CVD) risk factors, the daily dosage, duration of consumption, form of intake, and the specific variety of flaxseed (based on lignan content) are crucial factors. Full article
15 pages, 603 KiB  
Article
Exploring the Role of Self-Efficacy in Maintaining Healthy Lifestyle Habits among Patients with Cardiometabolic Diseases; Findings from the Multi-Center IACT Cross-Sectional Study
by Vasiliki Kalantzi, Thomas Tsiampalis, Matina Kouvari, Vasiliki Belitsi, Antonios Zairis, Athanasios Migdanis, Sousana K. Papadopoulou, Fotini Bonoti, Demosthenes B. Panagiotakos and Rena I. Kosti
Life 2024, 14(6), 736; https://doi.org/10.3390/life14060736 - 7 Jun 2024
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Abstract
(1) Background: Cardiometabolic disease progression can be delayed if patients engage in healthy lifestyle behaviors, adherence to which is highly influenced by psychosocial factors. The present study aimed at investigating the association of self-efficacy with the adherence level to healthy lifestyle behaviors among [...] Read more.
(1) Background: Cardiometabolic disease progression can be delayed if patients engage in healthy lifestyle behaviors, adherence to which is highly influenced by psychosocial factors. The present study aimed at investigating the association of self-efficacy with the adherence level to healthy lifestyle behaviors among patients with cardiometabolic diseases in Greece. (2) Methods: 1988 patients (1180 females) with cardiometabolic diseases participated. Anthropometric, demographic, socioeconomic, clinical, and lifestyle characteristics were recorded. Patients were also asked to evaluate their efficacy to comply with healthy lifestyle behaviors. (3) Results: The majority exhibited unhealthy lifestyle behaviors. A subgroup demonstrated elevated self-efficacy in maintaining healthy habits despite facing diverse psychosocial challenges. Individuals with higher educational attainment, socioeconomic status, and rural/semi-urban residency had significantly elevated self-efficacy. Those with heightened self-efficacy exhibited significantly lower BMI and reduced prevalence of certain health conditions. Self-efficacy significantly influenced adherence to the Mediterranean diet, physical activity engagement, and smoking cessation, even in challenging circumstances. (4) Conclusions: This study represented an innovative approach in examining the role of self-efficacy in shaping health behaviors and outcomes within a Greek population. By integrating specific psychosocial circumstances into the analysis, valuable insights were provided into the contextual factors influencing self-efficacy and adherence to healthy lifestyle behaviors. Full article
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