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Life
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Imaging of Neurovascular Diseases
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Imaging of Neurovascular Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Radiobiology and Nuclear Medicine".

Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 5861

Special Issue Editors

Dr. Marcin Sawicki

E-Mail Website
Guest Editor
Dept. of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University, Szczecin, Poland
Interests: neurovascular diseases; stroke; brain death; neuroradiology; computed tomography; computed tomography angiography; 4d computed tomography; magnetic resonance angiography; perfusion imaging; cerebral catheter angiography; transcranial Doppler ultrasound; artificial intelligence; machine learning
Prof. Dr. Romuald Bohatyrewicz

E-Mail Website
Guest Editor
Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland
Interests: brain death; neurocritical care; apnea test

Special Issue Information

Dear Colleagues,

Vascular neurology, vascular neurosurgery, and interventional neuroradiology are independent fields with dedicated training programs. Neuroimaging, and in particular what we call “neurovascular imaging”, is a unifying factor which can be considered the intersection of these three medical specialties. With this Special Issue, we aim to thoroughly cover the imaging techniques, potentialities, and present and future applications as applied to the vascular diseases of the central nervous system from an imaging point of view.

In recent years, several advances in imaging technology have dramatically expanded the frontiers of human investigation in the neurovascular field. We hope that this Special Issue will be a timely and complete addition to the growing body of literature on this topic.

Our aim is to cover all aspects of neurovascular disease in a comprehensive way.

Dr. Marcin Sawicki
Prof. Dr. Romuald Bohatyrewicz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • brain
  • imaging
  • neuroscience
  • neurovascular imaging
  • stroke

Published Papers (2 papers)

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Research

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10 pages, 1854 KiB  
Article
Preservation of Cerebellar Afferent Pathway May Be Related to Good Hand Function in Patients with Stroke
by Bo Kyung Shin, Hae-Yeon Park, Hanee Rim, Ji Yoon Jung, Sungwoo Paek, Yeun Jie Yoo, Mi-Jeong Yoon, Bo Young Hong and Seong Hoon Lim
Life 2022, 12(7), 959; https://doi.org/10.3390/life12070959 - 26 Jun 2022
Cited by 3 | Viewed by 1354
Abstract
Many chronic stroke patients suffer from worsened hand function, and functional recovery of the hand does not occur well after six months of stroke. Therefore, predicting final hand function after stroke through acute phase imaging would be an important issue in counseling with [...] Read more.
Many chronic stroke patients suffer from worsened hand function, and functional recovery of the hand does not occur well after six months of stroke. Therefore, predicting final hand function after stroke through acute phase imaging would be an important issue in counseling with the patients or their family. Thus, we investigated the remaining white matter integrity in the corticospinal tract (CST) and cortico-ponto-cerebellar tract (CPCT) at the acute stage of stroke and chronic hand function after stroke, and present the cut-off value of fiber number (FN) and fractional anisotropy (FA) of CST and CPCT at the acute stage for predicting final hand function after the recovery period. This retrospective case-control study included 18 stroke patients who were classified into two groups: poor hand function with stroke (n = 11) and good hand function with stroke (n = 7). DTI was done within two months ± 15 days after onset, and the Jebson’s Hand Function test was conducted 6–12 months after onset. The investigation of white matter was focused on the values of FN and FA for CST and CPCT, which were measured separately. The normalized (affected/non-affected) FA and FN values in the CPCT in the good hand function group were higher than those in the poor hand function group. The normalized FN and FA values in the CST were not significantly different between the poor hand function group and the good hand function group. The normalized cut-off value that distinguished the good hand function group from the poor hand function group was 0.8889 for FA in the CPCT. The integrity of the CPCT in the acute stage was associated with hand function in the chronic stage after a stroke. Ultimately, the integrity of the CPCT in the early stage after onset can be used to predict chronic hand function. Based on these results, cerebellar afferent fiber measurements may be a useful addition to predict hand function and plan specific rehabilitation strategies in stroke patients. Full article
(This article belongs to the Special Issue Imaging of Neurovascular Diseases)
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Review

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17 pages, 3651 KiB  
Review
Computed Tomography Angiography (CTA) in Selected Scenarios with Risk of Possible False-Positive or False-Negative Conclusions in Diagnosing Brain Death
by Gerhard Schwarz, Maximilian Errath, Placido Argüelles Delgado, Ulrike Wießpeiner, Henrika Voit-Augustin, Robert Grims, Friedrich Kaltenböck, Eva Maria Kober, Andreas Schöpfer and Gottfried Fuchs
Life 2022, 12(10), 1551; https://doi.org/10.3390/life12101551 - 6 Oct 2022
Cited by 1 | Viewed by 3518
Abstract
It is widely accepted that brain death (BD) is a diagnosis based on clinical examination. However, false-positive and false-negative evaluation results may be serious limitations. Ancillary tests are used when there is uncertainty about the reliability of the neurologic examination. Computed tomography angiography [...] Read more.
It is widely accepted that brain death (BD) is a diagnosis based on clinical examination. However, false-positive and false-negative evaluation results may be serious limitations. Ancillary tests are used when there is uncertainty about the reliability of the neurologic examination. Computed tomography angiography (CTA) is an ancillary test that tends to have the lowest false-positive rates. However, there are various influencing factors that can have an unfavorable effect on the validity of the examination method. There are inconsistent protocols regarding the evaluation criteria such as scoring systems. Among the most widely used different scoring systems the 4-point CTA-scoring system has been accepted as the most reliable method. Appropriate timing and/or Doppler pre-testing could reduce the number of possible premature examinations and increase the sensitivity of CTA in diagnosing cerebral circulatory arrest (CCA). In some cases of inconclusive CTA, the whole brain computed tomography perfusion (CTP) could be a crucial adjunct. Due to the increasing significance of CTA/CTP in determining BD, the methodology (including benefits and limitations) should also be conveyed via innovative electronic training tools, such as the BRAINDEXweb teaching tool based on an expert system. Full article
(This article belongs to the Special Issue Imaging of Neurovascular Diseases)
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