Organ Predilection of Certain Gastrointestinal Diseases—Pathophysiology, Diagnosis and Management
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (15 March 2026) | Viewed by 4670
Special Issue Editor
Special Issue Information
Dear Colleagues,
After many years of experience managing different gastrointestinal diseases, I find that different parts of the gastrointestinal tract have different disease predilections or are vulnerable to certain diseases. For example, ischemic bowel disease mainly occurs in the left colon, Crohn’s disease mainly occurs in the ileocecal region, ulcerative colitis starts from the rectum, there is a higher incidence of right-sided colon cancer in females compared to left-sided colon cancer in males, right-sided diverticular disease bleeds more than left-sided diverticular disease, and the ileocecal region is affected by Crohn’s disease, lymphoma, intestinal TB, CMV, yersinia infection, radiation enteritis, Behcet’s disease, ischemic small bowel stricture, and NSAID enteropathy. In total, 90% of small bowel neuroendocrine tumors occur in the distal ileum within 60 cm from the ileocecal valve. Small intestinal angioectasia is mainly seen in the proximal small bowel. Jejunal diseases may include infectious enteritis, diverticulosis, Crohn’s enteritis, ulcerative jejunoileitis secondary to Celiac disease, angioectasia, Behcet’s disease, neuroendocrine tumors, and obstruction due to stricture, adhesion, and malignancy. Duodenum can be affected by duodenitis, ulcers, neuroendocrine tumors, benign and malignant strictures, diverticulum, and Bouveret syndrome. Gastric antrum is more commonly affected by gastritis, peptic ulcer disease, gastric antral vascular ectasia and malignancy, fundus by portal hypertensive gastropathy, varices, autoimmune gastritis, and Dieulafoy lesion. Reflux esophagitis, Barrett’s esophagus, epidermoid metaplasia, adenocarcinoma, and esophageal varices are mostly seen in the distal esophagus. Eosinophilic esophagitis is a patchy disease and can affect the proximal, middle, and distal esophagus.
Primarily, we welcome submissions of high-quality original research articles showcasing new developments and innovative findings regarding these topics. Otherwise, we will consider high-interest review articles and case series of exceptional merit.
Dr. Monjur Ahmed
Guest Editor
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Keywords
- disease predilection in gastrointestinal tract
- esophagus with certain diseases
- stomach with certain diseases
- duodenum with certain diseases
- jejunum with certain diseases
- ileum with certain diseases
- colorectum with certain diseases
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