materials-logo

Journal Browser

Journal Browser

Advances in Implant Materials and Biocompatibility

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 805

Special Issue Editor


E-Mail Website
Guest Editor
Bioengineering, Faculty of Dentistry, University of Otago, Dunedin 9054, New Zealand
Interests: development of biomaterials, with a focus on those that are sustainable and biocompatible

Special Issue Information

Dear Colleagues,

With one eye cast toward the future, the aim of this Special Issue is to showcase rapidly evolving field of implant materials, with the latest research highlighting the transformative impact of advanced biocompatible materials.

As researchers, we have made momentous strides in advancements in material development, designing products that are compatible with the human body. When implanted, these materials show low rejection rates and high mechanical properties, but most importantly, they integrate into the surrounding tissues.

The topics of interest for this Special Issue include, but are not limited to, the following:

  • Nanostructured materials;
  • Hybrid biomaterials;
  • Composite materials to improve the mechanical properties of implants;
  • In vitro and in vivo studies on biocompatible materials designed for implants;
  • Implantable medical devices;
  • Drug/device combinations;
  • Surface modifications that enhance biocompatibility or functionality;
  • Emerging trends, future directions or significant advances.

Advances in life sciences and engineering continually challenge, expand and redefine the concepts of implant materials and biocompatibility. Every day, novel biomaterials, products and testing regimes are introduced into scientific research practices. The application of these new biomaterials and techniques can lead to significant clinical advances. It is these advancements that we are looking towards.  We are looking for scientific articles and reviews, but most of all, ground-breaking, novel articles on topics at the forefront of science.

Dr. Maree L. Gould
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biocompatibility
  • microscopy
  • bioceramics
  • biometals
  • biopolymers
  • hybrid materials
  • drug-releasing implants
  • cell impregnation in vitro and in vivo
  • three-dimensional scaffolds

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

15 pages, 4033 KiB  
Article
In Vivo and In Vitro Response to a Regenerative Dental Scaffold
by Maree L. Gould, Xiaoxuan Deng, Karl Lyons and Azam Ali
Materials 2024, 17(21), 5384; https://doi.org/10.3390/ma17215384 - 4 Nov 2024
Viewed by 602
Abstract
As dental pulp contains the stem cells necessary for regeneration, the tooth should hold the intrinsic capacity for self-repair. A triphasic hybrid dental biocomposite (3HB) composed of biocompatible biopolymers to provide strength, antibacterial properties and protein-based cell support could provide a conducive microenvironment [...] Read more.
As dental pulp contains the stem cells necessary for regeneration, the tooth should hold the intrinsic capacity for self-repair. A triphasic hybrid dental biocomposite (3HB) composed of biocompatible biopolymers to provide strength, antibacterial properties and protein-based cell support could provide a conducive microenvironment for the regeneration of dental structures. 3HB was incorporated into Mineral Trioxide Aggregate (ProRoot MTA) to construct a malleable injectable implant. Human tooth pulp cells (hDPCs) significantly increased proliferation in the presence of 3HB+MTA compared to 3HB or MTA alone. Cell viability decreased with MTA alone but increased with 3HB and 3HB+MTA. 3HB+MTA was implanted into the residual tooth of drilled Wistar rat M2 molars for up to 45 days. Stereological analysis from micro-CT images showed the volume of the tooth remaining. Histologically, regenerative pulpal architecture was seen invading 3HB. A continuous odontoblastic profile lined a deposit of dentin-like material suggesting reparative dentinogenesis. Overall, no infection or encapsulation was seen. Immunohistochemically, odontoblasts were seen along the margins of the wounded tooth undergoing repair. Mesenchymal cells (MSCs) were seen at the base of the drilled tooth and by 21 days had translocated into the implant itself. Cells stimulating remineralization were highly expressed in the tooth undergoing repair. CD146-positive MSCs were seen in the center of the implant, possibly stimulating remineralization. In conclusion, behavior of 3HB+ in vitro and in vivo provided a promising start as 3HB+MTA may serve as a viable regenerative scaffold for pulp regeneration; however, this should be further studied before clinical use can be considered. Full article
(This article belongs to the Special Issue Advances in Implant Materials and Biocompatibility)
Show Figures

Graphical abstract

Back to TopTop