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Biocompatibility of Dental Restorative and Prosthetic Materials: Where Are We...
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Biocompatibility of Dental Restorative and Prosthetic Materials: Where Are We Now and Where We Would Like to Go?

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 December 2022) | Viewed by 3295

Special Issue Editor

Prof. Dr. Alexandra Ripszky Totan

E-Mail Website
Guest Editor
1. Biochemistry Department, Dental Medicine Faculty, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
2. The Interdisciplinary Center for Dental Research and Development, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: dental materials biocompatibility; saliva biochemistry; oral cancer; oxidative stress
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

My colleagues and I would are pleased to invite both researchers and clinicians to submit research articles, review articles, and communications to this Special Issue.

The purpose of this Special Issue is to highlight new trends regarding dental restorative and prosthetic materials biocompatibility, and to reveal how our current knowledge may open new paths towards obtaining such materials with superior qualities, including improved oral biocompatibility.

Prof. Dr. Alexandra Ripszky Totan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prosthetic materials
  • restorative materials
  • CAD–CAM technologies
  • composite resins
  • monomer release
  • curing behaviour
  • wear resistance
  • polymerization
  • oxidative stress
  • inflammation
  • saliva

Published Papers (1 paper)

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Review

16 pages, 502 KiB  
Review
Toxicological Risks of the Cobalt–Chromium Alloys in Dentistry: A Systematic Review
by Brigitte Grosgogeat, Alina Vaicelyte, Rémy Gauthier, Christine Janssen and Marc Le Borgne
Materials 2022, 15(17), 5801; https://doi.org/10.3390/ma15175801 - 23 Aug 2022
Cited by 16 | Viewed by 2905
Abstract
Background: The toxicological risk of Co-Cr dental alloys is actually a sensitive subject with the European regulatory changes, namely regulation (EU) 2017/745 and annex VI to the CLP regulation (EC) 1972/2008. Objectives: The objective of this review is to conduct a rigorous [...] Read more.
Background: The toxicological risk of Co-Cr dental alloys is actually a sensitive subject with the European regulatory changes, namely regulation (EU) 2017/745 and annex VI to the CLP regulation (EC) 1972/2008. Objectives: The objective of this review is to conduct a rigorous analysis of the cytocompatibility of cobalt–chromium (Co-Cr) dental alloys. Considering various parameters such as cytotoxicity, type IV hypersensitivity reaction, sensitization, and irritation, we investigated evidence of toxicity of Co-Cr in human dental applications. Data sources: Specific search strategies were performed in three electronic databases, namely Medline, Embase, and Web of Science, using a main restriction in the search regarding the publication date (1995–2022). Study selection: Out of a total of 836 articles, only 21 studies were selected and analyzed according to PRISMA methodology. Results: Among them, 10 in vitro studies using human samples and 11 in vivo studies on human patients were distinguished. Most of the in vitro studies confirmed that Co-Cr alloys have a good cytocompatibility compared to Ni alloys. Regarding the in vivo studies, it appeared that Co-Cr could rarely cause sensitization, irritation, and allergic reactions. Reactions were mainly observed for people allergic to Co or Cr. Nevertheless, titanium-based materials showed better results. Conclusions: This study proposes a new state of the art on Co-Cr dental alloys and will thus be very useful for carrying out additional studies. Relevance: This review will help practitioners in their daily clinical choice. Full article
(This article belongs to the Special Issue Biocompatibility of Dental Restorative and Prosthetic Materials: Where Are We Now and Where We Would Like to Go?)
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