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Implantable Biomaterials: Design, Properties and Performance Evaluation

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 February 2022) | Viewed by 2080

Special Issue Editors


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Guest Editor
Department of Industrial, Electronic and Mechanical Engineering, Roma Tre University, Via Vito Volterra 62, 00146 Rome, Italy
Interests: functionalized surfaces; biomaterials; electrochemical characterizations; micro-FTIR material investigations; biopolymers

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Guest Editor
Department of Engineering, Roma Tre University, 00146 Rome, Italy
Interests: titania and titanium-based materials; drug delivery systems; bioactive coatings; hydroxyapatite; electrochemical characterization; electron microscopy

Special Issue Information

Dear Colleagues,

Implantable biomaterials undoubtedly play a central role in a wide variety of healthcare issues. These materials provide biocompatible supports to replace missing parts, deliver and protect biological active products (drugs and cells), and easily tune chemical and physicochemical properties to a specific target. Outstanding achievements have been made in the wide field of biomaterials research, yet the demand for further advances and a deeper understanding of the mechanisms underlying biocompatibility and bioactivity remains high.

This Special Issue of Materials on “Implantable Biomaterials: Design, Properties and Performance Evaluation” aims at bringing together recent advances in all the relevant aspects of the design of a successful biomedical implant that can be readily translated into clinical applications. Thus, we invite all colleagues to share contributions ranging from biomaterials development and characterization to the evaluation of biological performance, passing for surface functionalization and mechanical properties assessment.

We welcome original research and comprehensive review articles, analyzing implantable biomaterials from any possible perspective—this Special Issue is intended as an opportunity for different areas of expertise to intersect. We invite you to disseminate this invitation to all colleagues who may be interested.

Prof. Dr. Monica Orsini
Dr. Serena De Santis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metals
  • polymers
  • ceramics
  • physicochemical and mechanical properties
  • surface modification
  • biocompatibility
  • bioactivity enhancement
  • implant–host interactions

Published Papers (1 paper)

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Research

11 pages, 2510 KiB  
Article
A Nanoindentation Approach for Time-Dependent Evaluation of Surface Free Energy in Micro- and Nano-Structured Titanium
by Serena De Santis, Edoardo Rossi, Marco Sebastiani, Simona Sennato, Edoardo Bemporad and Monica Orsini
Materials 2022, 15(1), 287; https://doi.org/10.3390/ma15010287 - 31 Dec 2021
Cited by 6 | Viewed by 2120
Abstract
Surface free energy (SFE) of titanium surfaces plays a significant role in tissue engineering, as it affects the effectiveness and long-term stability of both active coatings and functionalization and the establishment of strong bonds to the newly growing bone. A new contact–mechanics methodology [...] Read more.
Surface free energy (SFE) of titanium surfaces plays a significant role in tissue engineering, as it affects the effectiveness and long-term stability of both active coatings and functionalization and the establishment of strong bonds to the newly growing bone. A new contact–mechanics methodology based on high-resolution non-destructive elastic contacting nanoindentation is applied here to study SFE of micro- and nano-structured titanium surfaces, right after their preparation and as a function of exposure to air. The effectiveness of different surface treatments in enhancing SFE is assessed. A time-dependent decay of SFE within a few hours is observed, with kinetics related to the sample preparation. The fast, non-destructive method adopted allowed for SFE measurements in very hydrophilic conditions, establishing a reliable comparison between surfaces with different properties. Full article
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