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Preparation, Characteristics and Application of Bioactive Glass

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced and Functional Ceramics and Glasses".

Deadline for manuscript submissions: closed (10 December 2023) | Viewed by 2114

Special Issue Editors

Department of Biomaterials, Alexander Dubcek University of Trencin, Trencin, Slovakia
Interests: bioactive glasses; tissue engineering; additive manufacturing; sol-gel method; surface modification; polyphenols; immunomudulation; hydrogels; nanoparticle; microsphere; porous materials; drug-loading; cardiovascular stents; anticoagulation; endothelialization

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Guest Editor
FunGlass–Centre for Functional and Surface Functionalized Glass, Alexander Dubcek University of Trenčín, Študentská 2, 911 50 Trenčín, Slovakia
Interests: bioactive glasses; tissue engineering; additive manufacturing; glass melting; sol-gel method; nanoparticle; microsphere fabrication; porous materials; mechanical properties; high performance ceramics

Special Issue Information

Dear Colleagues,

Bioactive glasses (BGs) were initially developed by Larry Hench et al. in the late 1960s. BGs are able to produce hydroxyapatite when they come into contact with physiological fluids and form strong bonds with bone and soft tissue. Meanwhile, the Si, P, and Ca ions released via the degradation of BGs can promote osteogenesis and angiogenesis. These properties of BGs make them one of the most promising materials for bone repair. Moreover, due to favourable features such as biodegradability and therapeutic ion release, BGs are also widely employed in other biomedical fields such as wound dressings, soft tissue regeneration, and tumour treatment.

Nowadays, new BG compositions are being developed to suit the requirements of different service environments, while the doping of inorganic cations brings additional biological functions, such as osteogenesis, angiogenesis, immunomodulation, and antibacterial and anti-inflammatory activities. A rich variety of manufacturing techniques, such as flame synthesis, sol–gel, foaming, templating, and additive manufacturing (selective laser sintering, stereolithography, 3D printing, ink-jet printing, robocasting, etc.) enable the fabrication of various dense or porous BG nano/micron particles and scaffolds to better meet clinical requests. In addition, BG surface modification, polymer/BG composites, BG hydrogels, and porous BG drug-loading are also current popular topics in research.

We cordially invite authors to contribute research articles or reviews relating to the broad range of topics mentioned above, or other exciting research topics related to the title of this Special Issue "Preparation, Characteristics and Application of Bioactive Glass to Bone Regeneration".

Dr. Si Chen
Dr. Martin Michálek
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • compositions, additive manufacturing
  • nanoparticles
  • microspheres
  • porous scaffolds
  • composites
  • hydrogels
  • immunomodulation
  • antibacterial
  • ions doping
  • surface modification
  • drug-loading

Published Papers (1 paper)

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Review

18 pages, 885 KiB  
Review
Effect of Thermal Treatments and Ion Substitution on Sintering and Crystallization of Bioactive Glasses: A Review
by Francesco Gerardo Mecca, Devis Bellucci and Valeria Cannillo
Materials 2023, 16(13), 4651; https://doi.org/10.3390/ma16134651 - 28 Jun 2023
Cited by 6 | Viewed by 1584
Abstract
Bioactive glasses (BGs) are promising materials for bone regeneration due to their ability to bond with living bone tissue. However, thermal stability and mechanical properties of BGs need improvement for better clinical performance. In this paper, we present an overview of the influence [...] Read more.
Bioactive glasses (BGs) are promising materials for bone regeneration due to their ability to bond with living bone tissue. However, thermal stability and mechanical properties of BGs need improvement for better clinical performance. In this paper, we present an overview of the influence of different ions on the sintering and crystallization of BGs. Specifically, this review focuses on the impact of thermal treatments on the crystallization of 45S5 and other significant BG compositions. Potential applications of these thermally treated BGs, such as scaffolds, BG-based composites, and thermally sprayed coatings, are explored. Moreover, the substitution of ions has been investigated as a method to enhance the thermal properties of BGs. Notably, zinc, potassium, and strontium have been studied extensively and have demonstrated promising effects on both the thermal and the mechanical properties of BGs. However, it is important to note that research on ion inclusion in BGs is still in its early stages, and further investigation is necessary to fully comprehend the effects of different ions on sintering and crystallization. Therefore, future studies should focus on optimizing the ion substitution method to improve the thermal, mechanical, and even biological properties of BGs, thereby enhancing their potential for various biomedical applications. Full article
(This article belongs to the Special Issue Preparation, Characteristics and Application of Bioactive Glass)
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