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Materials
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Advanced Bioactive Peptides
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Advanced Bioactive Peptides

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (26 March 2020) | Viewed by 2221

Special Issue Editors

Prof. Dr. Kátia F. Fernandes

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Guest Editor
Laboratório de Química de Polímeros, Instituto de Ciências Biológicas, ICB2, Campus Samambaia, Universidade Federal de Goiás, Goiânia 74690-900, GO, Brazil
Interests: polysaccharides; polymers; starch; immobilization; antioxidants
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Karla A. Batista

E-Mail Website
Guest Editor
Instituto Federal de Educação, Ciência e Tecnologia de Goiás, Goiânia, Goiás, Brazil
Interests: biomaterials; polymeric nanoparticles; drug delivery; enzyme immobilization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

Bioactive peptides are small molecules containing 2 to 20 amino acids, which present some activity that leads to a health benefit for the organism. Bioactive peptides can be synthesized as ribosomal or enzymatic products or can be encrypted in a protein sequence to be released after enzymatic hydrolysis. Several bioactivities have been ascribed to peptides, including antimicrobial, anti-inflammatory, antihypertensive, antidiabetic, antioxidant activity. Most of the knowledge about bioactive peptides is restricted to in vitro tests, which must be additionally submitted to in vivo or ex vivo trials to reinforce the importance and the possible benefits of these molecules for the purpose of health improvement.

This Special Issue is devoted to providing broad coverage of the advances in the knowledge of naturally-occurring and encrypted bioactive peptides from different sources. This issue seeks contributions in the form of research articles and reviews reporting in vitro bioactivity of peptides, highlighting peptides that have shown in vivo and ex vivo activity and potential applications for these materials. 

Prof. Kátia F Fernandes
Prof. Karla A. Batista
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Naturally-occurring
  • Encrypted
  • Sequencing
  • Purification
  • In vivo activity
  • Ex vivo activity
  • Applications
  • Bioactive peptides

Published Papers (1 paper)

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Research

14 pages, 291 KiB  
Article
Impact of Nisin-Producing Strains of Lactococcus lactis on the Contents of Bioactive Dipeptides, Free Amino Acids, and Biogenic Amines in Dutch-Type Cheese Models
by Monika Garbowska, Antoni Pluta and Anna Berthold-Pluta
Materials 2020, 13(8), 1835; https://doi.org/10.3390/ma13081835 - 13 Apr 2020
Cited by 10 | Viewed by 2025
Abstract
The goal of this study was to determine changes in contents of free amino acids, biogenic amines, and bioactive dipeptides (anserine and L-carnosine) in cheese models produced with the addition of nisin-producing strains of Lactococcus lactis over their ripening period. After 5 weeks [...] Read more.
The goal of this study was to determine changes in contents of free amino acids, biogenic amines, and bioactive dipeptides (anserine and L-carnosine) in cheese models produced with the addition of nisin-producing strains of Lactococcus lactis over their ripening period. After 5 weeks of ripening, contents of total biogenic amines in the cheese models with the addition of L. lactis strains were lower than in the control cheese model. The cheese models examined differed significantly in contents of free amino acids through the ripening period. Individual free amino acids, such as ornithine, were found in some of the cheese models, which is indicative of their specific microbial activities. Both anserine and L-carnosine were detected in all variants of the cheese models. After 5-week ripening, the highest total content of bioactive dipeptides was determined in the cheese models produced with the nisin-producing culture of L. lactis 11454 (142.15 mg∙kg−1). Full article
(This article belongs to the Special Issue Advanced Bioactive Peptides)
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