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Advanced Materials for Biochemical Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (10 July 2022) | Viewed by 5723

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Department of Polymer Chemistry and Technology, Faculty of Chemical Technology, Kaunas University of Technology, Kaunas, Lithuania
Interests: organic materials; synthesis; physicochemical properties; optical and spectroscopic properties; biomedicine; bioimaging; bio-related application; material characterization
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Special Issue Information

Dear Colleagues,

The Special Issue focuses on solving the dilemmas related to modern biomaterials, especially in the areas of advanced biomaterials, orthopedics, tissue engineering, pharmaceuticals and biomechanics, and medical equipment.

The aim and mission of the Special Issue is to present the current state of progress in research and development in the field of biomedical sciences and materials engineering. The Special Issue covers a broad spectrum of materials science research, including functional materials, theoretical analysis, synthesis and processing, characterization, and properties of compounds. Emphasis is placed on the interdisciplinary nature of materials science and issues at the forefront of the field, such as medical and bioengineering applications.

Dr. Dalius Gudeika
Guest Editor

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Keywords

  • biological application
  • medical application
  • advanced biomaterials
  • bioimaging
  • synthesis
  • biomedicine
  • pharmaceuticals and biomechanics
  • material characterization

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Published Papers (2 papers)

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Research

17 pages, 2460 KiB  
Article
Characterization of PLA/PCL/Green Mussel Shells Hydroxyapatite (HA) Biocomposites Prepared by Chemical Blending Methods
by Rifky Ismail, Tezara Cionita, Yin Ling Lai, Deni Fajar Fitriyana, Januar Parlaungan Siregar, Athanasius Priharyoto Bayuseno, Fariz Wisda Nugraha, Rilo Chandra Muhamadin, Agustinus Purna Irawan and Agung Efriyo Hadi
Materials 2022, 15(23), 8641; https://doi.org/10.3390/ma15238641 - 4 Dec 2022
Cited by 10 | Viewed by 2778
Abstract
Recently, there has been an increase in the number of studies conducted on the process of developing hydroxyapatite (HA) to use in biocomposites. HA can be derived from natural sources such as bovine bone. The HA usage obtained from green mussel shells in [...] Read more.
Recently, there has been an increase in the number of studies conducted on the process of developing hydroxyapatite (HA) to use in biocomposites. HA can be derived from natural sources such as bovine bone. The HA usage obtained from green mussel shells in biocomposites in this study will be explored. The research goal is to investigate the composition effect of biomaterials derived from polycaprolactone (PCL), polylactic acid (PLA), as well as HA obtained from green mussel shells with a chemical blending method on mechanical properties and degradation rate. First, 80 mL of chloroform solution was utilized to immerse 16 g of the PLA/PCL mixture with the ratios of 85:15 and 60:40 for 30 min. A magnetic stirrer was used to mix the solution for an additional 30 min at a temperature and speed of 50 °C and 300 rpm. Next, the hydroxyapatite (HA) was added in percentages of 5%, 10%, and 15%, as well as 20% of the PLA/PCL mixture’s total weight. It was then stirred for 1 h at 100 rpm at 65 °C to produce a homogeneous mixture of HA and polymer. The biocomposite mixture was then added into a glass mold as per ASTM D790. Following this, biocomposite specimens were tested for their density, biodegradability, and three points of bending in determining the effect of HA and polymer composition on the degradation rate and mechanical properties. According to the findings of this study, increasing the HA and PLA composition yields a rise in the mechanical properties of the biocomposites. However, the biocomposite degradation rate is increasing. Full article
(This article belongs to the Special Issue Advanced Materials for Biochemical Applications)
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15 pages, 4792 KiB  
Article
Rheological Properties of Different Graphene Nanomaterials in Biological Media
by Arisbel Cerpa-Naranjo, Javier Pérez-Piñeiro, Pablo Navajas-Chocarro, Mariana P. Arce, Isabel Lado-Touriño, Niurka Barrios-Bermúdez, Rodrigo Moreno and María Luisa Rojas-Cervantes
Materials 2022, 15(10), 3593; https://doi.org/10.3390/ma15103593 - 18 May 2022
Cited by 5 | Viewed by 2429
Abstract
Carbon nanomaterials have received increased attention in the last few years due to their potential applications in several areas. In medicine, for example, these nanomaterials could be used as contrast agents, drug transporters, and tissue regenerators or in gene therapy. This makes it [...] Read more.
Carbon nanomaterials have received increased attention in the last few years due to their potential applications in several areas. In medicine, for example, these nanomaterials could be used as contrast agents, drug transporters, and tissue regenerators or in gene therapy. This makes it necessary to know the behavior of carbon nanomaterials in biological media to assure good fluidity and the absence of deleterious effects on human health. In this work, the rheological characterization of different graphene nanomaterials in fetal bovine serum and other fluids, such as bovine serum albumin and water, is studied using rotational and microfluidic chip rheometry. Graphene oxide, graphene nanoplatelets, and expanded graphene oxide at concentrations between 1 and 3 mg/mL and temperatures in the 25–40 °C range were used. The suspensions were also characterized by transmission and scanning electron microscopy and atomic force microscopy, and the results show a high tendency to aggregation and reveals that there is a protein–nanomaterial interaction. Although rotational rheometry is customarily used, it cannot provide reliable measurements in low viscosity samples, showing an apparent shear thickening, whereas capillary viscometers need transparent samples; therefore, microfluidic technology appears to be a suitable method to measure low viscosity, non-transparent Newtonian fluids, as it is able to determine small variations in viscosity. No significant changes in viscosity are found within the solid concentration range studied but it decreases between 1.1 and 0.6 mPa·s when the temperature raises from 25 to 40 °C. Full article
(This article belongs to the Special Issue Advanced Materials for Biochemical Applications)
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