Data Modeling and Analysis in Epidemiology and Biostatistics

A special issue of Mathematics (ISSN 2227-7390). This special issue belongs to the section "E: Applied Mathematics".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1493

Special Issue Editors


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Guest Editor
1. Management Information Centre (MagiC), NOVA Information Management School, Universidade Nova de Lisboa, Lisboa, Portugal
2. Comprehensive Health Research Centre (CHRC), NOVA Medical School, Universidade NOVA de Lisboa, Lisboa, Portugal
Interests: Bayesian statistics; mathematical epidemiology; biostatistics

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Guest Editor
School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
Interests: biostatistics; Markov random fields; disease mapping; Bayesian hierarchical inference

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Guest Editor
NOVA Information Management School, Universidade Nova de Lisboa, Lisboa, Portugal
Interests: disease mapping; Gaussian random fields; Bayesian hierarchical modelling in medicine & life sciences

Special Issue Information

Dear Colleagues,

Integrating data analysis and modeling in epidemiology and biostatistics stands at the confluence of public health, mathematics, statistics, and computer science. At this intersection, we witness the most transformative advancements in understanding and combating health-related issues. The application of sophisticated data analysis and modeling techniques in epidemiology and biostatistics enables a profound insight into disease patterns, health trends, and the efficacy of interventions, significantly influencing public health policies and practices. However, effectively utilizing these methodologies necessitates a precise approach to formulating research questions, selecting appropriate models, and applying advanced computational techniques.

In light of the current advancements and the critical role of data analysis and modeling in addressing global health challenges, this Special Issue aims to highlight the innovative approaches and methodologies in epidemiology and biostatistics. It seeks to serve as a pivotal resource for professors, graduate students, and research scientists in both academic and practical public health settings, guiding the selection of the most suitable modeling and analytical methods to address complex health issues. Furthermore, this Special Issue aspires to capture the interest of a diverse audience engaged in the broader field of public health, data science, and statistical modeling, fostering a deeper understanding of the intricate relationship between data-driven methods and epidemiological insights.

We encourage contributions that explore new models, data analysis techniques, and their applications in epidemiology and biostatistics, including, but not limited to, infectious disease modeling, health data analytics, biostatistical methods for public health interventions, and computational approaches in genetic epidemiology. This Special Issue presents an opportunity to spotlight the critical bridges being built between data analysis, modeling, and the broader realm of epidemiology and biostatistics, encouraging cross-disciplinary collaboration and innovation.

Dr. Jorge M. Mendes
Dr. Ying C. MacNab
Dr. Helena Baptista
Guest Editors

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Keywords

  • epidemiology
  • environmental statistics in public health
  • biostatistics
  • data analysis
  • public health modeling
  • infectious disease modeling
  • health data analytics
  • statistical methods in medicine and public health
  • computational epidemiology
  • genetic epidemiology
  • disease surveillance systems
  • chronic disease modeling

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Published Papers (1 paper)

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Research

23 pages, 2050 KiB  
Article
Advances in Clinical Trial Design: Employing Adaptive Multiple Testing and Neyman Allocation for Unequal Samples
by Hanan Hammouri, Muna Salman, Mohammed Ali and Ruwa Abdel Muhsen
Mathematics 2025, 13(8), 1273; https://doi.org/10.3390/math13081273 - 12 Apr 2025
Viewed by 134
Abstract
This study introduces a new method that combines three distinct approaches for comparing two treatments: Neyman allocation, the O’Brien and Fleming multiple testing procedure, and a system of different sample weights at different stages. This new approach is called the Neyman Weighted Multiple [...] Read more.
This study introduces a new method that combines three distinct approaches for comparing two treatments: Neyman allocation, the O’Brien and Fleming multiple testing procedure, and a system of different sample weights at different stages. This new approach is called the Neyman Weighted Multiple Testing Procedure (NWMP). Each of these adaptive designs “individually” has proven beneficial for clinical research by removing constraints that can limit clinical trials. The advantages of these three methods are merged into a single, innovative approach that demonstrates increased efficiency in this work. The multiple testing procedure allows for trials to be stopped before their chosen time frame if one treatment is more effective. Neyman allocation is a statistically sound method designed to enhance the efficiency and precision of estimates. It strategically allocates resources or sample sizes to maximize the quality of statistical inference, considering practical constraints. Additionally, using different weights in this method provides greater flexibility, allowing for the effective distribution of sample sizes across various stages of the research. This study demonstrates that the new method maintains similar efficiency in terms of the Type I error rate and statistical power compared to the O’Brien and Fleming test while offering additional flexibility. Furthermore, the research includes examples of both real and hypothetical cases to illustrate the developed procedure. Full article
(This article belongs to the Special Issue Data Modeling and Analysis in Epidemiology and Biostatistics)
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