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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Anesthesia and Analgesia in Surgical Practice

edited by

Sang Yoong Park

and Chan Jong Chung

submission deadline 30 Apr 2025 | 11 articles | Viewed by 17130 | Submission Open

Keywords: pediatric anesthesia; airway management; meta-analysis; ultrasound-guided procedures; postoperative pain control; reduce opioid consumption; opioid-induced hyperalgesia; regional anesthesia; peripheral nerve block

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Clinical Profile and Treatment Response of Patients with Ocular Inflammation

edited by

Valeria Albano

and Giovanni Alessio

submission deadline 30 Apr 2025 | 4 articles | Viewed by 7471 | Submission Open

Keywords: ocular inflammation; anterior uveitis; posterior uveitis; intermediate uveitis; masquerade syndrome

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Medicine and Dentistry

edited by

Radu Iliescu

Ionut Luchian

and

Mihaela Moscalu

submission deadline 30 Apr 2025 | 6 articles | Viewed by 6993 | Submission Open

Keywords: physiology; biomarker; predictive modeling; risk classification methods; salivary diagnosis; cytokines; systemic diseases; genetics; microbiology; pharmacology; biostatistics

(This special issue belongs to the Section Dentistry and Oral Health)

Emerging Technologies in Lithotripsy: Challenges, Trends and Perspectives

edited by Maria Ordonez

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4666 | Submission Open

Keywords: holium; thulium; ureteroscopy; nephrolithiasis; nephrolithotomy

(This special issue belongs to the Section Urology & Nephrology)

Current Advances in Diagnosis and Surgical Treatment of the Head and Neck Disorders, 2nd Edition

edited by Poramate Pitak-Arnnop and

Christian Stoll

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2190 | Submission Open

Keywords: head and neck injury; head and neck trauma; head and neck cancer; oncology; head and neck infection; congenital orofacial deformity; orofacial pain; facial plastic and reconstructive surgery; facial aesthetic medicine; head and neck reconstruction

(This special issue belongs to the Section Surgery)

Treatment of Neurological Diseases—Current and Emerging Applications

edited by

Hyunjoong Kim

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1811 | Submission Open

Keywords: neurological diseases; neurodegenerative diseases; neuroprotection; gene therapy; cell therapy; neuroimaging; neuromodulation; precision medicine; artificial intelligence; rehabilitation

(This special issue belongs to the Section Neurology)

Current Status and Progress in Laparoscopic Surgery

edited by

Natalia Dowgiałło-Gornowicz

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1757 | Submission Open

Keywords: laparoscopic surgery; laparoscopy; cholecystectomy; appendectomy; bariatric surgery; minimally invasive surgery; surgical innovations

(This special issue belongs to the Section Surgery)

Diagnostic and Therapeutic Updates on Hair and Nail Disorders

edited by

Elisa Camela

and Sonia Sofía Ocampo-Garza

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1722 | Submission Open

Keywords: hair disorders; scarring alopecia; non-scarring alopecia; nail disorders; diagnosis; management; anti-cancer treatment; personalized medicine

(This special issue belongs to the Section Dermatology)

Novel Innovations in Diabetes Mellitus Prevention, Screening and Management

edited by

Anca Pantea Stoian

Teodor Salmen

and

Mihaela Adela Iancu

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1120 | Submission Open

Keywords: diabetes mellitus; prevention; screening; complications; cardiovascular disease; neuropathy; retinopathy; nephropathy

(This special issue belongs to the Section Endocrinology)

Recent Advances in Metabolic Syndrome and Its Comorbidities: The Scourge of the 21st Century

edited by Eleni Geladari and Vassilios Sevastianos

submission deadline 30 Apr 2025 | 1 articles | Viewed by 823 | Submission Open

Keywords: metabolic syndrome; hypertension; diabetes mellitus; dyslipidemia; cardiovascular disease; metabolic dysfunction-associated steatotic liver disease (MASLD); chronic kidney disease; hypogonadism; hepatocellular carcinoma; extrahepatic neoplasms

(This special issue belongs to the Section Endocrinology)

Prophylaxis, Diagnosis, and Treatment Strategies of Gastric Cancer

edited by Nadim Al Hajjar and Andra Ciocan

submission deadline 30 Apr 2025 | Viewed by 622 | Submission Open

Keywords: gastric cancer; treatment; prevention; diagnosis; surveillance; follow-up; neoadjuvant therapy; prognosis; biomarkers

(This special issue belongs to the Section Oncology)

Advances in the Diagnosis and Treatment of Coronary Artery and Peripheral Artery Diseases

edited by

Ovidiu Mitu

and

Alexandru Dan Costache

submission deadline 30 Apr 2025 | 1 articles | Viewed by 544 | Submission Open

Keywords: peripheral artery disease; coronary artery disease; cardiac rehabilitation; cardiovascular prevention; revascularisation; percutaneous coronary intervention; coronary artery bypass graft

(This special issue belongs to the Section Cardiology)

Updates on Endovascular Management of Peripheral Arterial Disease

edited by Giulio Illuminati, Eugenio Stabile and Rocco Pasqua

submission deadline 30 Apr 2025 | Viewed by 465 | Submission Open

Keywords: peripheral artery disease; limb ischemia; peripheral interventions; endovascular interventions; endovascular therapies; image-guided therapies; interventional devices

(This special issue belongs to the Section Cardiology)

Valve Diseases: Diagnosis and Treatment Innovations

edited by Vincenzo Caruso and Rajdeep Bilkhu

submission deadline 30 Apr 2025 | Viewed by 364 | Submission Open

Keywords: minimally invasive surgery; trans-catheter valve intervention; hybrid cardiac surgery; heart team; valve repair; Ross procedure; infective endocarditis

(This special issue belongs to the Section Cardiology)

Clinical Updates and Future Perspectives in Dental and Maxillofacial Surgery

edited by Ali-Farid Safi

submission deadline 30 Apr 2025 | Viewed by 246 | Submission Open

Keywords: oral surgery; maxillofacial surgery; trends; future perspectives; innovations; biomaterials; precision; regenerative medicine

(This special issue belongs to the Section Dentistry and Oral Health)

Development of Cancer Surgery: Innovations in Gastrointestinal, Endocrine, and HPB Cancer Treatment

edited by

Justas Žilinskas

Tadas Latkauskas

and

Saulius Švagždys

submission deadline 30 Apr 2025 | Viewed by 191 | Submission Open

Keywords: gastrointestinal cancer; endocrine surgery; hepatopancreatobiliary (HPB) cancer; minimally invasive surgery; postoperative care; liquid biopsies; fluorescence-guided surgery; enhanced recovery after surgery (ERAS); biomarkers; patient-centered care

(This special issue belongs to the Section Gastroenterology & Hepatology)

Diabetes in Old Age

edited by

Salvatore Corrao

and

Christiano Argano

submission deadline 30 Apr 2025 | Viewed by 190 | Submission Open

Keywords: old age; diabetes; treatment-related concerns; personalized strategies; management; polypharmacy; technologies; comorbidities; functional disabilities

(This special issue belongs to the Section Endocrinology)

Hematopoietic Stem Cell Transplantation: Current Trends and Future Perspectives

edited by

Lucia Prezioso

and Federica Galaverna

submission deadline 30 Apr 2025 | Viewed by 162 | Submission Open

Keywords: allogenic stem cell transplantation; GVHD; infections; stem cell manipulation; acute myeloid leukemia; acute lymphoblastic leukemia; lymphoproliferative disorders; hemoglobinopathies; autoimmune disease; immune reconstitution; minimal residual disease

(This special issue belongs to the Section Hematology and Immunology)

Intensive Care and Life Support

edited by

Vedran Kovačić

submission deadline 30 Apr 2025 | Viewed by 138 | Submission Open

Keywords: acute organ failure; mechanical ventilation; nutrition in ICU; renal replacement therapy; extracorporeal blood purification; extracorporeal membrane oxygenation; cardiopulmonary resuscitation; external pacing; hepatic support

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advance in the Diagnosis, Treatment and Prognosis of Hepatocellular Carcinoma

edited by

Emdio Scarpellini

submission deadline 15 May 2025 | 8 articles | Viewed by 25516 | Submission Open

Keywords: hepatocellular carcinoma; metabolic-associated fatty liver disease; hepatic disease

(This special issue belongs to the Section Gastroenterology & Hepatology)

Chronic Respiratory Diseases: Updates on Pathophysiology, Symptoms, Diagnosis and Treatment

edited by

Marcin Kurowski

, Laura Malinauskienė and

Corrado Pelaia

submission deadline 15 May 2025 | 7 articles | Viewed by 11110 | Submission Open

Keywords: asthma; COPD; obstructive lung diseases; chronic rhinosinusitis with/without polyps; allergic rhinitis; allergic rhinoconjunctivitis; lower airways; upper airways

(This special issue belongs to the Section Pulmonology)

Early Detection and Clinical Treatment of Acute Kidney Injury

edited by

Yu-Jang Su

submission deadline 15 May 2025 | 3 articles | Viewed by 6621 | Submission Open

Keywords: acute kidney injury; poisoning; trauma; infectious disease; critical care

(This special issue belongs to the Section Urology & Nephrology)

Advances and Challenges in Stroke Rehabilitation

edited by

Trinidad Sentandreu-Mañó

and

José Manuel Tomás Miguel

submission deadline 15 May 2025 | Viewed by 326 | Submission Open

Keywords: stroke rehabilitation; neuroplasticity; therapeutic strategies; biopsychosocial approach; personalized medicine; AI-driven strategies; telemedicine; assessment measures; long-term support; healthcare disparities

Clinical Treatment of Neuroendocrine Neoplasm

edited by Michele Klain and

Leandra Piscopo

submission deadline 15 May 2025 | Viewed by 159 | Submission Open

Keywords: neuroendocrine neoplasms; neuroendocrine cell system; gastro-entero-pancreatic NENs; immunohistochemical analysis; Ki-67 index; mitotic count; somatostatin analogue therapy; antiproliferative effect; positron emission tomography/computed tomography (PET/CT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Oncology)

Advances in Bypass Surgery in Cardiology

edited by

Giuseppe Nasso

and

Ignazio Condello

submission deadline 20 May 2025 | 2 articles | Viewed by 2263 | Submission Open

Keywords: Coronary Artery Bypass Grafting (CABG); minimally invasive cardiac surgery; cardiopulmonary bypass; hybrid coronary revascularization; off-pump surgery; myocardial protection; surgical outcomes in cardiology

(This special issue belongs to the Section Cardiology)

Thoracic Oncologic Surgery: Current Progress and Future Directions

edited by

Emmanouil Kapetanakis

submission deadline 20 May 2025 | 1 articles | Viewed by 1639 | Submission Open

Keywords: thoracic surgical oncology; lung cancer; thoracic surgery; video-assisted thoracic surgery (VATS); robotic-assisted thoracic surgery (RATS)

(This special issue belongs to the Section Surgery)

Ophthalmology: New Diagnostic and Treatment Approaches

edited by

Stephen G. Schwartz

, Krishna S. Kishor, Víctor Manuel Villegas, Christopher Leffler and

Andrzej Grzybowski

submission deadline 25 May 2025 | 5 articles | Viewed by 3688 | Submission Open

Keywords: ophthalmology; ocular imaging; anti-vascular endothelial growth factor agents; complement inhibitors; intraocular surgery; genetic testing; intraocular lenses

(This special issue belongs to the Section Ophthalmology)

Clinical Applications of Modern Technologies in Neurosurgery and Spine Surgery

edited by

Mirza Pojskić

Christopher Nimsky

and

Miriam Bopp

submission deadline 30 May 2025 | 5 articles | Viewed by 13749 | Submission Open

Keywords: modern technologies; neuronavigation; augmented reality; virtual reality; robotics; endoscopy; tumor treating fields; tumor biology; intraoperative ultrasound; intraoperative computed tomography; intraoperative magnetic resonance imaging; neuroradiology; neurosurgery; spine surgery

(This special issue belongs to the Section Neurology)

Extracorporeal Membrane Oxygenation (ECMO): New Insights and Future Directions

edited by Jeffrey D. DellaVolpe

submission deadline 30 May 2025 | 4 articles | Viewed by 4766 | Submission Open

Keywords: ECMO; extracorporeal life support; technology; innovation; prediction; biomarkers

(This special issue belongs to the Section Pulmonology)

Recent Advances in Maternal–Fetal Medicine

edited by

Demetra Socolov

Dragos Nemescu

and

Ingrid Andrada Vasilache

submission deadline 30 May 2025 | 2 articles | Viewed by 1331 | Submission Open

Keywords: maternal– fetal medicine; prenatal screening; artificial intelligence; personalized medicine; prenatal imaging

(This special issue belongs to the Section Obstetrics and Gynecology)

Anterior Cruciate Ligament (ACL) Injury

edited by

Riccardo D'Ambrosi

and Alessandro Carrozzo

submission deadline 30 May 2025 | 1 articles | Viewed by 1217 | Submission Open

Keywords: anterior cruciate ligament; anterolateral ligament; arthroscopy; knee; sports medicine

(This special issue belongs to the Section Orthopedics)

Head and Neck Cancers: Modern Management

edited by Lucian Miron,

Camil Mirestean

and Dragos Teodor Iancu

submission deadline 30 May 2025 | Viewed by 236 | Submission Open

Keywords: head and neck cancers; image-guided radiotherapy; stereotactic body radiosurgery (SBRT); proton therapy; carbon ion therapy; radiobiological models; immunotherapy; targeted therapy; secondary cancers; oligo-metastatic

(This special issue belongs to the Section Oncology)

Advances in Cancer Therapy from Research to Clinical Practice—Surgical, Molecular or Systemic Management of Cancer: 2nd Edition

edited by

Călin Căinap

and Nicolae Crisan

submission deadline 31 May 2025 | 11 articles | Viewed by 30653 | Submission Open

Keywords: cancer; systemic therapy; surgery; molecular; research

(This special issue belongs to the Section Oncology)

Chronic Stress and Obesity: Psychology, Nutrition and Modern Lifestyle Behavior

edited by

Joanna Rog

and Napoleon Waszkiewicz

submission deadline 31 May 2025 | 6 articles | Viewed by 15202 | Submission Open

Keywords: obesity; psychological stress; lifestyle behaviors; physical activity; quality of sleep; diet; nutrition; stress-reducing methods; yoga; meditation; wellbeing; lifestyle medicine

(This special issue belongs to the Section Psychiatry)

Advances in Cancer Multimodal Approaches: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies, 2nd Edition

edited by

Daniel Alin Cristian

and

Valentin Titus Grigorean

submission deadline 31 May 2025 | 5 articles | Viewed by 9170 | Submission Open

Keywords: cancer; mechanism; surgery; multimodal; advances

(This special issue belongs to the Section Oncology)

Clinical Cardiology in a New Era: Navigating Challenges and Embracing Opportunities

edited by Rayan Yousefzai and Cindy M. Martin

submission deadline 31 May 2025 | 4 articles | Viewed by 5447 | Submission Open

Keywords: cardiovascular medicine; cardiology subspeciality; cardiomyopathy

(This special issue belongs to the Section Cardiology)

Advancements in Dental Medicine, Oral Anesthesiology and Surgery

edited by Cosmin Sinescu,

Ciprian Roi

and

Mircea Riviș

submission deadline 31 May 2025 | 4 articles | Viewed by 3946 | Submission Open

Keywords: oral surgery; oral anesthesiology; implantology and guided surgery; oral tissue regeneration; periodontal disease; dental materials; oral medical devices; oral diseases

(This special issue belongs to the Section Dentistry and Oral Health)

DPP-4 Inhibitors: Navigating the Intersection of Heart Health, Kidney Function, and Diabetes Management

edited by

Francisco Epelde

submission deadline 31 May 2025 | 2 articles | Viewed by 3271 | Submission Open

Keywords: DPP-4 inhibitors; heart failure; kidney insufficiency; cardiovascular health; diabetes management; non-diabetic patients; endothelial regulation; inflammation modulation; chronic kidney disease; nephropathy

(This special issue belongs to the Section Cardiology)

Male Infertility: A Contemporary Review on Present Status and Future Perspective

edited by

Nikolaos Sofikitis

submission deadline 31 May 2025 | 2 articles | Viewed by 2051 | Submission Open

Keywords: male infertility; assisted reproductive technologies; sperm DNA fragmentation; genetic screening; oxidative stress; hormonal therapy; IVF/ICSI; biomarkers; gene therapy; reproductive health

(This special issue belongs to the Section Urology & Nephrology)

Update on Orthopedic Anesthesia

edited by

Annachiara Marra

Maria Vargas

and Antonio Coviello

submission deadline 31 May 2025 | 1 articles | Viewed by 1864 | Submission Open

Keywords: loco-regional anesthesia; orthopedic surgery; postoperative pain; peripheral nerve blocks; adjuvants; neuraxial anesthesia; complications

(This special issue belongs to the Section Orthopedics)

Minimally Invasive Procedures in Cardiac Care

edited by

Antonello D’Andrea

Vincenzo Russo

and

Alfredo Mauriello

submission deadline 31 May 2025 | 1 articles | Viewed by 1609 | Submission Open

Keywords: minimally invasive cardiac care; valve surgery; coronary artery bypass grafting; heart failure management; surgical techniques; implantable cardioverter defibrillator; pacemaker; stellate ganglion blockage; aortic valve; mitral valve; hybrid approaches

(This special issue belongs to the Section Cardiology)

Advances in Gynecological Cancer Research: Emerging Technologies and Future Therapeutic Strategies

edited by Jae-Yun Song and

Seongmin Kim

submission deadline 31 May 2025 | 1 articles | Viewed by 1540 | Submission Open

Keywords: gynecological cancer; innovative surgical techniques; genomic profiling; personalized medicine; artificial intelligence (AI) in oncology; machine learning in diagnosis; cancer research technologies; future therapeutic strategies

(This special issue belongs to the Section Obstetrics and Gynecology)

Impact of Exercise on Neuropsychiatric and Cognitive Symptoms

edited by

Claudia Brogna

submission deadline 31 May 2025 | 1 articles | Viewed by 1240 | Submission Open

Keywords: development; autism spectrum disorders; ADHD; intellectual disabilities; dyspraxia; sport; physical exercise; neuromuscular disorders

(This special issue belongs to the Section Neurology)

The Impact of Altitude on Exercise Tolerance of Various Patients

edited by

Martin Burtscher

Daniel Neunhaeuserer

and Silvia Ulrich

submission deadline 31 May 2025 | 1 articles | Viewed by 1167 | Submission Open

Keywords: high altitude; hypoxia; exercise; exercise limitation; chronic diseases; chronic lung disease; chronic heart disease; sleep apnea; arterial hypertension; pulmonary hypertension

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Epilepsy, Seizures, and Sleep Disorders

edited by Giedrė Jurkevičienė, Evelina Pajediene and Renata Balnyte

submission deadline 31 May 2025 | 2 articles | Viewed by 1083 | Submission Open

Keywords: epilepsy; seizure; antiseizure medications; adverse effects of anti-seizure medications; quality of life; electroencephalography; sleep; sleep disorders; insomnia; daytime sleepiness; sleep– wake rhythm; circadian; hypersomnia; narcolepsy

(This special issue belongs to the Section Neurology)

Diabetic Retinopathy: Current Understanding and Treatment Strategies

edited by

Rossella D'Aloisio

and Marco Rocco Pastore

submission deadline 31 May 2025 | 1 articles | Viewed by 780 | Submission Open

Keywords: diabetes mellitus; diabetic retinopathy; diabetic macular edema; retinal imaging; anti-vascular endothelial growth factor injections; dexamethasone implant; vitreoretinal surgery; photocoagulation laser; diabetic eye-screening program; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

From Conception to Birth: Embryonic Development and Disease

edited by

Paschalis Theotokis

, Soultana Meditskou and

Maria Eleni Manthou

submission deadline 31 May 2025 | Viewed by 302 | Submission Open

Keywords: embryology; organogenesis; cell differentiation; gametes; reproduction; sex ratio; birth defects; pathophysiology; disease

Recent Advances in Anesthesiology and Pain Medicine

edited by Adam Rudnik and

Izabela Duda

submission deadline 31 May 2025 | 1 articles | Viewed by 248 | Submission Open

Keywords: anesthetic procedures; perioperative monitoring; airway management; pain management; standards of anesthesia; perioperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Acute and Chronic Pancreatitis, Pancreatic Malignancies: 2nd Edition

edited by

Žilvinas Dambrauskas

Povilas Ignatavicius

and Antanas Gulbinas

submission deadline 31 May 2025 | Viewed by 217 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; benign tumors of the pancreas; pancreatic cystic lesions; pancreatic cancer; cancer immunity; molecular mechanisms of carcinogenesis and drug resistance; pancreatic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatology)

Laparoscopic Surgery in Colorectal Cancer

edited by Bogdan Diaconescu and Adrian Daniel Tulin

submission deadline 31 May 2025 | Viewed by 215 | Submission Open

Keywords: laparoscopy; colorectal cancer; minimally invasive surgery; colon surgery; general surgery; colorectal surgery

(This special issue belongs to the Section Oncology)

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