Angina Pectoris - Pathogenesis and Management

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 217

Special Issue Editor


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Guest Editor
Clinic of Cardiac and Vascular Diseases, Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania
Interests: cardiogenic shock; assisted circulation; ventricular assist device; aortic stenosis; transcatheter aortic valve implanta-tion; echocardiography
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Special Issue Information

Dear Colleagues,

Chest angina is a typical occurrence for patients with coronary artery disease when chest pain is caused by increased oxygen demand in the myocardium in its inadequate supply. It is one of the most common symptoms studied in cardiology. The incidence of angina is 20–40 thousand per 1 million people in the majority of European countries.

Since there are many possible causes for chest pain, the general approach for the initial diagnostic management of patients with angina or suspected obstructive coronary artery disease has changed in the last few years. In the past, exercise ECG testing and cardiac ultrasound were the main methods used for the diagnosis of patients. Now, more sophisticated methods, such as cardiac CT angiography or imaging testing and single-photon emission computerized tomography, stress echocardiography and stress magnetic resonance imaging for ischemia, are recommended. Nevertheless, significant coronary stenoses are responsible for only half of the patients presenting with angina and the symptoms may be due to coronary vasomotor disorders, for example microvascular dysfunction or epicardial spasm.

After the diagnosis confirmation, appropriate therapies must be initiated, which include lifestyle management, medical therapy and revascularization when indicated. Optimal medical treatment should aim to reduce angina symptoms, to reduce exercise-induced ischemia, and to prevent future cardiovascular events. Revascularization improves the symptom control and survival rate of patients with a severe course and poor prognosis of the disease. The treatment recommendations should follow the latest ESC guidelines for chronic coronary syndromes.

Prof. Dr. Pranas Šerpytis
Guest Editor

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Keywords

  • coronary artery disease
  • stable angina
  • microvascular dysfunction
  • epicardial spasm
  • pharmacotherapy
  • revascularization

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