Opportunities and Challenges for Treating Pancreatic Cancer
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 30 December 2024 | Viewed by 101
Special Issue Editor
Interests: RNA biology; transcriptomics; alternative splicing; drug–DNA interactions; inflammation; cancer biology; pancreatic cancer; pancreatitis; gastroenterology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pancreatic cancer (PC) is a malignant tumor that is difficult to detect in its early stages and has a relatively rapid progression and a poor prognosis. It is currently ranked as the third leading cause of cancer-related deaths in the US and is projected to become the second leading cause of cancer-related deaths in the US by 2030. Chemotherapy and surgery are the main treatment options for PC patients, but due to its deceptive onset, only 15%–20% of patients are eligible for surgery at the time of diagnosis and most patients are often in the advanced or inoperable stage of the disease at the time of their initial diagnosis. Currently, there is a lack of effective early detection or screening methods and biomarkers that can accurately and reliably detect early-stage PC or its precursor lesions. Furthermore, not much therapeutic success has been achieved with radiation treatment, chemotherapy, and immunotherapy. Therefore, the exploration of new biomarkers for the early detection of the disease, the better understanding of the involved signaling pathways, tumor microenvironment, and precise surgical and therapeutic interventions is urgently required.
This Special Issue aims to embrace the recent developments in pancreatic cancer research that can address these challenges.
We look forward to receiving your contributions.
Dr. Hassan Mubarak Ishqi
Guest Editor
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Keywords
- pancreatic cancer
- PDAC
- immunotherapy
- biomarkers
- immune checkpoint inhibitors
- chemotherapy
- signaling pathways
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