Revolutionizing Cardiopulmonary Resuscitation: Contemporary Advances and Challenges

Dear Colleagues,

Cardiopulmonary resuscitation is a vital medical procedure used to revive individuals from life-threatening conditions, primarily focusing on restoring normal breathing and blood circulation. Over the years, this field has witnessed profound innovations that extend beyond basic techniques to include mechanical aids, advanced pharmacological interventions, and sophisticated monitoring technologies.

The Special Issue, titled "Revolutionizing Cardiopulmonary Resuscitation: Contemporary Advances and Challenges", addresses the latest advancements and obstacles in pre-clinical, clinical, and community-based settings within the domain of resuscitation. This issue aims to comprehensively explore the entire spectrum of resuscitation, from experimental research and clinical trials to practical applications in real-world scenarios, such as community response systems.

In pre-clinical settings, the focus is on developing and testing new resuscitation techniques and technologies, such as mechanical resuscitation devices and advances in pharmacological agents, which are evaluated for efficacy and safety before clinical application. Clinical advancements include the integration of these new technologies and methods into hospital and emergency care, emphasizing evidence-based practices and the importance of rapid, effective response techniques. These advancements cover the full range of resuscitation, from early recognition systems to post-resuscitation care and neuroprognostication. Moreover, this Special Issue incorporates advancements in related topics, such as airway management, ventilation, peri-arrest arrhythmias, shock, cardiac monitoring, point-of-care ultrasound, and non-technical skills in emergency settings.

Community-based challenges and innovations, such as public access defibrillation programs and training for non-medical personnel, are highlighted to emphasize the importance of immediate response in increasing survival rates outside of medical facilities. Challenges of note include the scientific hurdles in developing reliable and effective resuscitation methods, the practical issues of implementing these advancements uniformly across different regions and communities, and ethical considerations.

Below is a non-exhaustive list of specific topics of interest:

• Animal models of cardiopulmonary resuscitation in preclinical research (rats, mice, swine, etc.);
• Life-support training for non-medical personnel;
• Early recognition systems for deteriorating patients;
• Neuroprognostication after resuscitation;
• Temperature management after resuscitation;
• Non-technical skills in the emergency setting;
• Extracorporeal CPR (eCPR);
• Public access defibrillation;
• Shock;
• Anaphylaxis;
• Artificial intelligence in cardiopulmonary resuscitation.

All types of manuscripts are welcome for submission, including full-length original articles, reviews (narrative and systematic with/without meta-analysis), and high-quality case reports.

Dr. Georgios Mavrovounis
Dr. Ioannis Pantazopoulos
Dr. Maria Mermiri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cardiopulmonary resuscitation
• defibrillation
• mechanical CPR
• emergency medicine
• automated external defibrillator
• e-CPR
• post-resuscitation period
• neurological outcomes