Acute Respiratory Distress Syndrome and Lung Injury: From Diagnosis to Treatment

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Pulmonology".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 269

Special Issue Editor


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Guest Editor
Department of Neonatology, University Medicine Mannheim, 68167 Mannheim, Germany
Interests: ECMO; lung failure in newborns; pulmonary hypertension; diaphragmatic hernia
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Special Issue Information

Dear Colleagues,

Acute Respiratory Distress Syndrome (ARDS) and lung injury represent significant challenges in critical care, demanding swift and accurate diagnosis, followed by prompt treatment to improve patient outcomes. ARDS is characterized by severe inflammation and fluid accumulation in the lungs, leading to impaired gas exchange and respiratory failure. While its causes range from pneumonia to sepsis, the syndrome's hallmark is its rapid onset, necessitating early recognition.

Diagnosing ARDS requires a careful assessment of clinical symptoms, imaging, and exclusion of cardiac causes. The widely used Berlin definition classifies ARDS based on the degree of hypoxemia, offering a framework for diagnosis. However, the heterogeneity of its presentation often complicates timely identification.

Treatment strategies for ARDS have evolved, with low tidal volume ventilation as a cornerstone, reducing ventilator-induced lung injury. Adjunctive therapies like prone positioning and extracorporeal membrane oxygenation (ECMO) offer additional support for severe cases. Yet, no pharmacological treatment has shown definitive benefit, highlighting the need for ongoing research.

In conclusion, ARDS remains a critical condition with high mortality.

Therefore, we are looking for basic, clinical and translational research papers and reviews focussing on advances in diagnostic precision and treatment modalities, as well as research on early intervention and personalized care approaches.

Prof. Dr. Thomas Schaible
Guest Editor

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Keywords

  • Acute Respiratory Distress Syndrome
  • lung injury
  • ECMO
  • pulmonary hypertension
  • diaphragmatic hernia
  • diagnostic precision
  • early treatment

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