The Impact of Environmental Contaminants on Neurodevelopment and Human Metabolism

A special issue of Metabolites (ISSN 2218-1989).

Deadline for manuscript submissions: 31 July 2025 | Viewed by 133

Special Issue Editors


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Guest Editor
Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80250-060, Brazil
Interests: mercury; lead; selenium; neurodevelopment; brain; oxidative stress; bi-omarkers; antioxidant system
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Guest Editor
Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80250-060, Brazil
Interests: pesticides; pharmaceuticals; phthalates; endocrine disruptors; environmental contaminants; neurodevelopment; metabolism; oxidative stress; biomarkers; antioxidant system

Special Issue Information

Dear Colleagues,

Anthropogenic activities have been contributing to the exponential increase of pollutants released into the environment. The perinatal period represents a critical and vulnerable period for the developing brain. This way, exposure to environmental contaminants, such as metals, pesticides, phthalates, and other emerging contaminants, can affect the organism's metabolism. Developing individuals are more sensitive when challenged with xenobiotics. A particular concern is regarding the morphology and physiology of the developing brain. Alterations during neurodevelopment can compromise important functions of the individual's nervous system and cause permanent health problems, such as learning, memory, and behavioral deficits.

Studying the effects of environmental contaminants isolated or in mixtures, especially in realistic concentrations, in different models/organisms (rodents, fish, cell culture, etc.) and the effects in several pathways of organisms' development and metabolism is pivotal to understanding the effects of anthropogenic actions on human health.

In this Special Issue, papers exploring new biomarkers of exposure, new pathways affected, and biochemical and molecular alterations caused by exposure to environmental contaminants (especially pesticides and metals) are welcome.

Dr. Cláudia Sirlene de Oliveira
Dr. Izonete Cristina Guiloski
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pesticides
  • metals
  • mercury
  • methylmercury
  • developing organism
  • oxidative stress

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Published Papers

This special issue is now open for submission.
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