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Metabolites publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine Learning Applications in Metabolomics Analysis

edited by

Leonardo Franco

and

Martin Grootveld

submission deadline 30 Jun 2024 | 7 articles | Viewed by 8069 | Submission Open

Keywords: metabolites; biofluids; Artificial Intelligence; metabolomics; machine learning

(This special issue belongs to the Section Bioinformatics and Data Analysis)

Novel Approaches for Metabolomics in Drugs and Biomarkers Discovery

edited by

Cecília R.C. Calado

submission deadline 30 Jun 2024 | 5 articles | Viewed by 7273 | Submission Open

Keywords: metabolomics; drugs discovery; biomarkers discovery; diagnostic; prognosis

(This special issue belongs to the Section Advances in Metabolomics)

Preclinical and Clinical Application of Metabolomics in Medicine

edited by

Eleftherios Panteris

and

Olga Deda

submission deadline 30 Jun 2024 | 4 articles | Viewed by 6539 | Submission Open

Keywords: metabolomics; metabolic profiling; lipidomics; biomarker discovery; personalized medicine; precision medicine; animal models; machine learning; analytical techniques

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

Exploring Potential Diagnostic and Prognostic Salivary Biomarkers in Cancer—2nd Edition

edited by

Lyudmila Bel'skaya

and

Martin Grootveld

submission deadline 30 Jun 2024 | 2 articles | Viewed by 4778 | Submission Open

Keywords: salivary biomarkers; metabolomics; salivaomics; diagnosis; prognosis; cancer

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Challenges and Opportunities in Application of Mass Spectrometry for Metabolomics and Lipidomics

edited by

Konstantinos Kouremenos

and

David J. Beale

submission deadline 30 Jun 2024 | 4 articles | Viewed by 4565 | Submission Open

Keywords: metabolomics; lipidomics; separation science; mass spectrometry; bioinformatics

(This special issue belongs to the Section Metabolomic Profiling Technology)

Mass Spectrometry-Based Metabolomics and Lipidomics for Biomarker Discovery and Drug Development

edited by

Ala F. Nassar

submission deadline 30 Jun 2024 | 4 articles | Viewed by 3939 | Submission Open

Keywords: mass spectrometry; lipidomics; metabolomics; single-cell analysis; metabolism; pharmacology

(This special issue belongs to the Section Advances in Metabolomics)

Impact of Food and Bioactive Compounds on Metabolic Diseases

edited by

Bungo Shirouchi

and

Hayato Maeda

submission deadline 30 Jun 2024 | 3 articles | Viewed by 1732 | Submission Open

Keywords: food factors; bioactive compounds; food function; metabolism; metabolites; gut microbiota (flora); metabolic syndrome; metabolic diseases (disorders)

(This special issue belongs to the Section Nutrition and Metabolism)

Lipidomics in Health and Disease

edited by

Paul Wood

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1729 | Submission Open

Keywords: lipidomics; high-resolution mass spectrometry; lipid derivatization; lipid chromatography; diagnostics; therapeutics

(This special issue belongs to the Section Lipid Metabolism)

Mass Spectrometry-Based Metabolomics Identification of Plant Components

edited by

Robert Winkler

submission deadline 30 Jun 2024 | Viewed by 535 | Submission Open

Keywords: mass spectrometry; plant biochemistry; natural products; nutritional value; bioactive compounds; chemoinformatics

(This special issue belongs to the Section Plant Metabolism)

Metabolic Responses of Seeds Development and Germination

edited by

Li Li

and

Mingxun Chen

submission deadline 30 Jun 2024 | Viewed by 252 | Submission Open

Keywords: stress; seeds; seedling; metabolism; hormone regulation; development

(This special issue belongs to the Section Plant Metabolism)

The Role of Hemorheology, Microcirculation, and Metabolism in Clinical Research

edited by

Barbara Sándor

and Miklós Rábai

submission deadline 30 Jun 2024 | Viewed by 127 | Submission Open

Keywords: hemorheology; microcirculation; red blood cell properties; viscosity; inflammation; metabolism

(This special issue belongs to the Section Cell Metabolism)

The Roles of Diet, Gut Microbiome and Microbial Metabolome in Precision Nutrition

edited by Renny S. Lan and

Jiangjiang Zhu

submission deadline 1 Jul 2024 | Viewed by 157 | Submission Open

Keywords: metabolomics; gut microbiome; precision nutrition; diet; integration; integrative; lipidomic; person-alized nutrition; probiotics; prebiotics; microbiota

(This special issue belongs to the Section Nutrition and Metabolism)

Metabolic Function and Mechanism of Enteroendocrine Cells and Gut Hormones

edited by

Varsha Singh

and Julie G. In

submission deadline 5 Jul 2024 | Viewed by 191 | Submission Open

Keywords: enteroendocrine cells; nutrient absorption; appetite; gut hormone; metabolic function

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Nutritional Strategies for Nutrient Metabolism Disorders in Animals under Stress

edited by

Xiao Xu

Kan Xiao

and

Dan Wang

submission deadline 10 Jul 2024 | 2 articles | Viewed by 3515 | Submission Open

Keywords: animals; nutrition; stress; metabolism; intestine; performance

(This special issue belongs to the Section Animal Metabolism)

Adipose Tissue, Reproduction and Metabolic Health in Women

edited by

Aldo Ferreira-Hermosillo

and Renata Saucedo

submission deadline 10 Jul 2024 | 1 articles | Viewed by 1087 | Submission Open

Keywords: adiposity; gestational diabetes; preeclampsia; pregnancy; obesity; polycystic ovarian syndrome; infertility; reproductive health

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolic Responses of Plants to Abiotic Stress

edited by

Baoguo Du

and

Youjun Zhang

submission deadline 15 Jul 2024 | 8 articles | Viewed by 9575 | Submission Open

Keywords: climate change; abiotic stress; carbohydrates; nitrogen metabolism; metabolomics; ROS and antioxidants; memory effects; secondary metabolites; epigenetic regulations

(This special issue belongs to the Section Plant Metabolism)

Metabolomics in Disease Mechanisms and Drug Targets

edited by

Kefeng Li

submission deadline 15 Jul 2024 | 1 articles | Viewed by 2325 | Submission Open

Keywords: metabolomics; disease mechanism; drug target; biomarker; disease prediction

(This special issue belongs to the Section Metabolomic Profiling Technology)

Exploring and Expanding Horizons in Secondary Metabolites: Biosynthesis, Identification, Regulation and Biological Activity

edited by

Alberto Jorge Oliveira Lopes

Antônio Cantanhede Filho

and Claúdia Quintino Da Rocha

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1374 | Submission Open

Keywords: secondary metabolites; biosynthesis; regulation; identification; plants; microorganisms; marine organisms; animals; bioactivity; drug discovery; natural products

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

The Role of Metabolites in Translational and Clinical Pharmacology

edited by

Mayur K. Ladumor

, Xinning Yang, Eva Berglund and Rheem A. Totah

submission deadline 15 Jul 2024 | Viewed by 908 | Submission Open

Keywords: metabolism; transport; ADME; PK; DDI; special populations; endogenous metabolite biomarker; PBPK and PK/PD modeling

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

Inflammation and Oxidative Stress in Age-Related Metabolic Changes and Disorders

edited by

Sylwia Dzięgielewska-Gęsiak

Teresa Grzelak

and Grzegorz Dziubanek

submission deadline 15 Jul 2024 | Viewed by 351 | Submission Open

Keywords: nutritional attitudes and behaviors; bioconcentration factor; health risk assessment; dietary exposure; farm-fresh foods; medicinal plants; gut microbiota; dietary supplements; trace elements— Zn; Cu; heavy metals

(This special issue belongs to the Section Nutrition and Metabolism)

Glucose Metabolism in Pregnancy

edited by Moen Gunn-Helen

submission deadline 20 Jul 2024 | 1 articles | Viewed by 1314 | Submission Open

Keywords: glucose metabolism; gestational diabetes; pregnancy; diabetes; glucose

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

The Emerging Role of Metabolomics in Epidemiological Studies of Atherosclerosis and Cardiovascular Disease

edited by

Hao Peng

Chenwei Pan

and

Changwei Li

submission deadline 20 Jul 2024 | Viewed by 543 | Submission Open

Keywords: cardiovascular disease; epidemiology; metabolic disease; metabolomics; multi-omics

(This special issue belongs to the Section Advances in Metabolomics)

The Role of Hepatic Insulin Clearance in Obesity and Type 2 Diabetes

edited by

Morvarid Kabir

and Richard N. Bergman

submission deadline 25 Jul 2024 | Viewed by 222 | Submission Open

Keywords: insulin clearance; insulin resistance; type 2 diabetes; obesity; hyperinsulinemia

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Natural Metabolites on Gut Microbiome Modulation

edited by

Shaohua Wang

submission deadline 30 Jul 2024 | 2 articles | Viewed by 7706 | Submission Open

Keywords: natural metabolites; gut microbiome; gut microbiome modulator; human health; human diseases

(This special issue belongs to the Section Advances in Metabolomics)

LC-MS Method Development and Metabolomics Data Analysis

edited by Chaevien S. Clendinen and Lisa Bramer

submission deadline 30 Jul 2024 | Viewed by 296 | Submission Open

Keywords: LC– MS; data visualization; mass spectrometry; NMR; chromatography; metabolomics; lipidomics

(This special issue belongs to the Section Bioinformatics and Data Analysis)

Mass Spectrometry Imaging: Theory, Methods and Applications in Biochemical and Pharmaceutical Research

edited by

Xiaowei Song

submission deadline 31 Jul 2024 | 4 articles | Viewed by 4393 | Submission Open

Keywords: in situ ionization; MS imaging data processing; multimodular imaging; spatial multi-omics; clinical diagnosis; drug research and development; cancer metabolism

(This special issue belongs to the Section Metabolomic Profiling Technology)

Unlocking the Mysteries of Muscle Metabolism in the Animal Sciences

edited by

David E. Gerrard

and

Sally E. Johnson

submission deadline 31 Jul 2024 | 3 articles | Viewed by 2336 | Submission Open

Keywords: muscle; amino acid metabolism; energy metabolism; metabolites; protein; growth

(This special issue belongs to the Section Animal Metabolism)

Advances in Salivary Metabolomics for Oral and Systemic Diseases

edited by

Arja Kullaa

submission deadline 31 Jul 2024 | 2 articles | Viewed by 2158 | Submission Open

Keywords: metabolomics; salivary metabolites; oral diseases; oral cancer; periodontal diseases; oral microbiome; systemic diseases

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolomic Profiling in Equine Medicine and Reproduction

edited by

Marilena Bazzano

and Fulvio Laus

submission deadline 31 Jul 2024 | 1 articles | Viewed by 1707 | Submission Open

Keywords: metabolomic analysis; horse; donkey; mule; equine medicine; equine reproduction; biomarker; metabolite; metabolome

(This special issue belongs to the Section Animal Metabolism)

Recent Advances in Radiation Research

edited by

Karol Jelonek

submission deadline 31 Jul 2024 | 1 articles | Viewed by 1685 | Submission Open

Keywords: ionizing radiation; radiotherapy; space radiation; radiation protection; metabolomics; lipidomics; multi-omics

(This special issue belongs to the Section Advances in Metabolomics)

Metabolic Biomarkers and Nutrition in Degenerative Conditions and Gastrointestinal Cancer Surgery

edited by

Irene Lidoriki

Dimitrios Schizas

and Maximos Frountzas

submission deadline 31 Jul 2024 | 1 articles | Viewed by 1406 | Submission Open

Keywords: biomarkers; nutrition; metabolism; metabolomics; degenerative disease; Parkinson’ s disease; Alzheimer’ s disease; cardiovascular disease; gastrointestinal cancer surgery

(This special issue belongs to the Section Nutrition and Metabolism)

Drug Metabolism and New Drug Development for Cancers

edited by

Anna Jelińska

and

Szymon Tomczak

submission deadline 31 Jul 2024 | 1 articles | Viewed by 1402 | Submission Open

Keywords: cancer; new drug development; metabolites; secondary plant metabolites; drug delivery; nanoformulation; anticancer treatment

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

Targeting Microbiota and Metabolites for Prevention and Treatment of Human Diseases

edited by

Zhipeng Tao

and

Danhui Wang

submission deadline 31 Jul 2024 | 2 articles | Viewed by 961 | Submission Open

Keywords: microbiota; metabolites; metabolic diseases; cancer; cardiovascular diseases; liver diseases

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Changing Diagnosis, Treatment and Monitoring of Rare Genetic Disorders in the -Omics Era

edited by Adviye Ayper Tolun and

Kaustuv Bhattacharya

submission deadline 31 Jul 2024 | Viewed by 234 | Submission Open

Keywords: inborn errors of metabolism; rare genetic diseases; clinical metabolomics; multiomics; biomarker discovery

(This special issue belongs to the Section Integrative Metabolomics)

New Perspectives in the Diagnosis and Treatment of Type 2 Diabetes and Its Complications

edited by Péter Kempler and Zsuzsanna Putz

submission deadline 31 Jul 2024 | Viewed by 213 | Submission Open

Keywords: type 2 diabetes mellitus; microvascular complications; diabetic neuropathy; diabetic nephropathy; diabetic retinopathy; glucose database analysis

(This special issue belongs to the Section Nutrition and Metabolism)

Brain Metabolism Models and Research

edited by Jennifer M. Lynch and

Tiffany S. Ko

submission deadline 31 Jul 2024 | Viewed by 141 | Submission Open

Keywords: brain mitochondria; brain oxidative stress; neuroinflammation; brain insulin signaling; brain lipid metabolism; brain aging; neurodegenerative diseases; neurodevelopmental disorders; microbiome and brain

(This special issue belongs to the Section Nutrition and Metabolism)

Metabolites and Thyroid

edited by Carolina Castro Porto Silva Janovsky and Caroline Serrano-Nascimento

submission deadline 1 Aug 2024 | Viewed by 245 | Submission Open

Keywords: metabolomics; hypothyroidism; hyperthyroidism; thyroid cancer; thyroid function; endocrine disruptors; lipidomics; proteomics

(This special issue belongs to the Section Nutrition and Metabolism)

New Insights on the Role of Lipid Metabolism in the Development of Cardiac Dysfunction

edited by

Stephen C. Kolwicz

submission deadline 1 Aug 2024 | Viewed by 227 | Submission Open

(This special issue belongs to the Section Lipid Metabolism)

Metabolomics-Based Biomarkers for Nutrition and Health

edited by Cheng Zheng and

Daniel Raftery

submission deadline 2 Aug 2024 | 1 articles | Viewed by 1040 | Submission Open

Keywords: biomarker; metabolomics; nutritional epidemiology; disease diagnostics and prevention; risk prediction

(This special issue belongs to the Section Nutrition and Metabolism)

Sports: Nutrition and Metabolism in Relation to Athletes’ Health and Performance

edited by

Vassilis Mougios

submission deadline 5 Aug 2024 | 4 articles | Viewed by 4166 | Submission Open

Keywords: sports; physiology; metabolism; nutrition; rapid weight loss; body mass maintenance; performance; energy system contributions

(This special issue belongs to the Section Nutrition and Metabolism)

Effects of Biotic/Abiotic Stress on Plant Metabolism

edited by

Mohamed Ait-El-Mokhtar

Raja Ben-Laouane

and

Abdelilah Meddich

submission deadline 13 Aug 2024 | 8 articles | Viewed by 11573 | Submission Open

Keywords: biotic and abiotic stresses; plant primary and secondary metabolites; plant stress response; plant metabolomics; biologically active plant metabolites; phytochemical composition of plant metabolites; biotechnological production of plant metabolites; biostimulants for plant stress mitigation

(This special issue belongs to the Section Plant Metabolism)

Lifestyle Interventions: A Challenging Therapeutic Strategy for Metabolic Syndrome 2nd Edition

edited by

and

submission deadline 15 Aug 2024 | 1 articles | Viewed by 1963 | Submission Open

Keywords: diabetes; metabolic syndrome; insulin resistance; obesity

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Nutrition and Metabolism in Human Diseases 2nd Edition

edited by

Xinhui Wang

submission deadline 15 Aug 2024 | 1 articles | Viewed by 1112 | Submission Open

Keywords: nutrition; metabolism; nutrient; metabolite; disease

(This special issue belongs to the Section Nutrition and Metabolism)

Honorary Special Issue Dedicated to Prof. Giovanni Targher–the Metabolic Fatty Liver Syndromes: MASLD/MAFLD/NAFLD

edited by

Alessandro Mantovani

and

Amedeo Lonardo

submission deadline 15 Aug 2024 | 1 articles | Viewed by 660 | Submission Open

Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); metabolic dysfunction-associated steatotic liver disease (MASLD); fatty liver

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Reactive Oxygen Species and Energy Metabolic Alterations in Health and Disease

edited by

Paola Maycotte

and

Álvaro Marín-Hernández

submission deadline 15 Aug 2024 | Viewed by 180 | Submission Open

Keywords: cancer; ROS; glycolysis; mitochondria; autophagy; antioxidant system; glutathione; oxidative phosphorylation

(This special issue belongs to the Section Cell Metabolism)

Effect of Exogenous or Endogenous Regulatory Factors on Metabolic Responses of Plants to Biotic/Abiotic Stress

edited by

Bo Yuan

submission deadline 18 Aug 2024 | 1 articles | Viewed by 1240 | Submission Open

Keywords: biotic and abiotic stresses; biochemistry and biosynthesis of secondary metabolites; stress response and metabolic regulation; plant metabolomics under stress; lipid metabolism; root exudates composition under stress; exogenous or endogenous regulatory factors; ROS and antioxidants; plant regulation signaling pathways; plant growth promotion and metabolic mechanism

(This special issue belongs to the Section Plant Metabolism)

Metabolomic Advances in Promoting Exercise-Induced Metabolic Changes

edited by

Alex Castro

and Mara Patrıcia Traina Chacon-Mikahi

submission deadline 20 Aug 2024 | 5 articles | Viewed by 7579 | Submission Open

Keywords: metabolome; metabolites; exercise; physical activity; metabolic signatures

(This special issue belongs to the Section Advances in Metabolomics)

Cellular Metabolism in Neurological Disorders

edited by

Wenting Guo

Laura Fumagalli

and

Teodoro Bottiglieri

submission deadline 20 Aug 2024 | 3 articles | Viewed by 7210 | Submission Open

Keywords: metabolism ; neurodegeneration ; mitochondria ; glycogen; therapeutic targets; neurons; glia

(This special issue belongs to the Section Cell Metabolism)

Neuronutrition: Metabolomic Insights and Perspectives

edited by

Abraham Wall Medrano

and Rocío Campos Vega

submission deadline 30 Aug 2024 | Viewed by 1885 | Submission Open

Keywords: neuronutrition; neurological disorders; nutrition; functional foods; nutraceutical; nutrition physiology; nutriomics

(This special issue belongs to the Section Nutrition and Metabolism)

Metabolism in Aquatic Products

edited by Kuohsun Chiu

submission deadline 30 Aug 2024 | 1 articles | Viewed by 1714 | Submission Open

Keywords: metabolism; physiology; marine biology; fish; shellfish; nutrition; seafood; aquatic organism

(This special issue belongs to the Section Animal Metabolism)

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