Metabolism of New Psychoactive Substances: Medical, Toxicological and Analytical Aspects
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: closed (30 June 2023)
Special Issue Editor
Interests: new psychoactive substances; psychopharmacology; improving the quality of world biostatistics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, we have been dealing with a growing problem, which is the increase in the frequency of hospitalizations of patients abusing new psychoactive substances (NPS). What is very dangerous in the case of NPS is their poor toxicological diagnosis. Detection and determination of NPS is very difficult due to the constantly increasing number of compounds, especially with similar chemical structures. NPS pose great difficulties due to their action on the organism in much lower doses than classic drugs and the rapid and numerous metabolic changes that they undergo in the body. Patients usually do not take the new psychoactive substance alone but they combine it with other psychoactive substances. This makes it difficult to determine whether the given NPS is responsible for the clinical symptoms, or whether other substances that are additionally present. This often entails the use of polypharmacy in the treatment of this group of patients. Such a practice, sometimes resulting from the doctor's helplessness in the face of many symptoms of poisoning with these substances, is a big problem not only for psychiatry. It leads to a vicious circle effect that results in subsequent hospitalizations of these people. For this reason, the purpose of this special edition is to publish articles by the authors, namely on the medical, toxicological, and analytical aspects of taking diverse types of NPS. The submitted manuscripts may cover topics such as the determination of the level of NPS and their metabolites, as well as the study of their impact on the quality of patients’ life. The articles recommended for submission may also cover any analytical and toxicological dimensions related to the determination of NPS.
Dr. Michal Ordak
Guest Editor
Manuscript Submission Information
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Keywords
- new psychoactive substances
- “legal highs”
- designer drugs
- toxicology
- psychopharmacology
- analytical chemistry
- addiction
- metabolites
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