Evaluation of Metabolic Changes in Mice under Chronic Toxic Substances Exposure

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Environmental Metabolomics".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 10

Special Issue Editors


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Guest Editor
Genome Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS/NIH), 105 T. W. Alexander Drive RTP, Durham, NC 27709, USA
Interests: metabolomics; environmental contaminant; persistent organic pollutant; mass spectrometry; proteomics; toxicant; toxicological assessment; chronic toxicity; xenobiotic metabolism; lipidomics; dose-response relationship; molecular toxicology

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Guest Editor
Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Interests: environmental contaminant; mass spectrometry; metabolomics; proteomics; metagenomics; nuclear receptor; pesticide; toxicological assessment; risk assessment; pathogenesis; system biology; exposome; DNA adduct; lipidomics
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Special Issue Information

Dear Colleagues,

This Special Issue of Metabolites focuses on evaluating the metabolic alterations in mice subjected to chronic exposure to toxic substances, including environmental contaminants and persistent organic pollutants (POPs). The scope of this Special Issue covers comprehensive studies utilizing metabolomics, proteomics, lipidomics, and advanced mass spectrometry to explore how these toxicants disrupt metabolic pathways. Research examining dose–response relationships, xenobiotic metabolism, and chronic toxicity assessment in murine models is particularly encouraged.

The purpose of this Special Issue is to provide new insights into the molecular toxicology of chronic exposure, helping to identify biomarkers for toxicological assessment and better understand the long-term health risks posed by environmental contaminants. By gathering cutting-edge research on metabolic responses to toxicant exposure, this Special Issue aims to further our understanding of how chronic environmental exposure affects health, with implications for both animal and human studies. Potential authors are invited to submit experimental and review articles that address these critical questions using innovative approaches and contribute to advancing the field of toxicology and environmental health.

Dr. Yun-Chung Hsiao
Prof. Dr. Kun Lu
Guest Editors

Manuscript Submission Information

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Keywords

  • metabolomics
  • environmental contaminant
  • persistent organic pollutant
  • mass spectrometry
  • proteomics
  • toxicant
  • toxicological assessment
  • chronic toxicity
  • xenobiotic metabolism
  • lipidomic
  • dose–response relationship
  • molecular toxicology

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Published Papers

This special issue is now open for submission.
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