Immunometabolism and Metabolomics in Lung Disease
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 81
Special Issue Editors
Interests: pulmonary rare diseases; IPF; ILD; alpha 1-antitrypsin deficiency; COPD; lung physiopathology; metabolomics in lung pathology
Interests: COPD; lung physiopathology; pulmonary rare diseases; IPF; ILD; alpha 1-antitrypsin deficiency; metabolomics in lung pathology
Special Issue Information
Dear Colleagues,
Metabolomics is the science that investigates the metabolites present in biologic samples, thus inferring with the metabolic and biologic pathways behind their production. More specifically, Metabolomics refers to the systematic analysis of analytes (the so-called metabolites) in a biologic matrix, attempting to identify biomarkers of disease or metabolic processes. In recent years, Metabolomics has started to be recognized as a useful scientific tool to unravel disease mechanisms and to integrate what genetics already can explain about lung diseases. In the future, Metabolomics is expected to clarify several mechanisms in both obstructive and restrictive lung diseases, such as Chronic Obstructive Lung Disease (COPD) and Interstitial Lung Disease (ILD), together with Pulmonary Vascular Disease and Lung Cancer. Moreover, the pathways of immunometabolism behind lung diseases are a topic that Metabolomics can successfully help in clarifying. Today, the determination of metabolomic profiles relies on different analytical methods and technologies, i.e., Mass Spectrometry (MS) and Nuclear Magnetic Resonance Spectroscopy (NMRS). Among the most used biomatrices for Metabolomics analysis are exhaled breath condensate (EBC) and plasma and bronchoalveolar lavage fluid (BALF).
The aim of this Special Issue is to collect clinical research and basic science studies to comprehensively explore the topic of Metabolomics and immunometabolism in lung diseases. Original articles and reviews are welcome.
Dr. Claudio Tirelli
Prof. Dr. Stefano Centanni
Guest Editors
Manuscript Submission Information
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Keywords
- metabolomics
- lung physiopathology
- biomarkers
- COPD
- ILD
- nuclear magnetic resonance spectroscopy
- mass spectrometry
- exhaled breath condensate
- metabolites
- immunometabolism
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