Additively Manufactured of Metals and Alloys for Biomedical Applications

A special issue of Metals (ISSN 2075-4701). This special issue belongs to the section "Biobased and Biodegradable Metals".

Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 5883

Special Issue Editor


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Guest Editor
School of Mechanical Engineering, University of Campinas, Campinas, SP, Brazil
Interests: additive manufacturing; biomaterials; biofabrication; materials science

Special Issue Information

Dear Colleagues,

Over the past decades, there has been a considerable increase in the number of researches related to biomaterials development and its manufacturing processes. The expectation was that these researches would generate an increase in the performance of medical devices used in various medical fields such as orthopedic, dentistry, neurology, cardiology, etc.

Regarding biomedical metal alloys, special attention has been paid to the development of materials free of cytotoxic elements, such as Al, V, Cr, Co, and Ni, and still present adequate mechanical properties to mimic the biomechanical tissue behavior, with good interaction with the host tissue. On the other hand, research in manufacturing processes aimed to provide techniques that would allow the surface functionalization and also increase the freedom of geometric shapes. In this sense, additive manufacturing techniques have brought numerous advantages to the field of biomedical applications. Special mention is about the possibility of producing architectural structures that can reduce the rigidity of the implant, avoiding, for example, stress shielding in bone applications. In addition, these architectural structures can be designed with interconnected porous structures that allow for better interaction at the tissue-implant interface and also can be used as scaffolds.

Finally, some additive manufacturing techniques allow the manufacture of customized implants, given the degree of precision and freedom of creating geometric shapes. Other techniques allow the manufacture of biodegradable metals and medical devices with a functionally graded properties that can contemplate the variation of chemical composition, microstructure, porosity of architected structures, etc.

The purpose of this Special Issue is to collect manuscripts related to various aspects of research on additive manufacturing of metallic biomaterials. Original manuscripts will be welcomed on research related to processing, post-processing, characterization, and applications of biomedical metals and alloys.

Prof. Dr. Eder Socrates Najar Lopes
Guest Editor

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Keywords

  • additive manufacturing
  • 3D-printing
  • metallic biomaterials
  • biodegradable metals
  • functionally graded materials
  • biomedical applications
  • architected structures
  • scaffolds
  • post-processing

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Published Papers (2 papers)

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Research

15 pages, 6099 KiB  
Article
Wear Resistance of Plasma Electrolytic Oxidation Coatings on Ti-6Al-4V Eli Alloy Processed by Additive Manufacturing
by Pedro Bell Santos, Victor Velho de Castro, Estela Kerstner Baldin, Cesar Aguzzoli, Guilherme Arthur Longhitano, André Luiz Jardini, Éder Sócrates Najar Lopes, Antonio Marcos Helgueira de Andrade and Célia de Fraga Malfatti
Metals 2022, 12(7), 1070; https://doi.org/10.3390/met12071070 - 23 Jun 2022
Cited by 14 | Viewed by 2908
Abstract
The additive manufacturing (AM) technique can produce Ti-6Al-4V ELI (extra low interstitial) alloy for personalized biomedical devices. However, the Ti-6Al-4V ELI alloy presents poor tribological behavior. Regarding this, coatings are a feasible approach to improve the wear resistance of this alloy. In the [...] Read more.
The additive manufacturing (AM) technique can produce Ti-6Al-4V ELI (extra low interstitial) alloy for personalized biomedical devices. However, the Ti-6Al-4V ELI alloy presents poor tribological behavior. Regarding this, coatings are a feasible approach to improve the wear resistance of this alloy. In the literature, the tribological behavior of TiO2 coatings incorporated with Ca and P formed by one-step plasma electrolytic oxidation (PEO) on Ti-6Al-4V ELI alloy processed by AM has not been investigated. Thus, in the present work, it was studied the influence of Ti-6Al-4V ELI alloy processed by AM on the wear resistance and morphologic of the coating obtained by PEO (plasma electrolytic oxidation). In this way, three different voltages (200, 250, and 300 V) were employed for the PEO process and the voltage effect on the properties of the coatings. The coatings were characterized by contact profilometry, scanning electron microscopy, energy-dispersive spectroscopy, the sessile drop method, grazing-incidence X-ray diffraction, and wear tests, on a ball-on-plate tribometer. The increase in applied voltage promoted an increase in roughness, pore area, and a decrease in the pore population of the coatings. In addition, the coatings, mainly composed of anatase and rutile, showed good adhesion to the metallic substrate, and the presence of bioactive elements Ca and P were detected. The thickness of the coatings obtained by PEO increases drastically for voltages higher than 250 V (from 4.50 ± 0.33 to 23.83 ± 1.5 µm). However, coatings obtained with lower voltages presented thin and dense layers, which promoted a superior wear resistance (increase in wear rate from 1.99 × 10−6 to 2.60 × 10−5 mm3/s). Finally, compared to the uncoated substrate, the PEO coatings increased the wear resistance of the titanium alloy obtained by AM, also showing a superior wear resistance compared to the commercial Ti-6Al-4V alloy previously evaluated, being such a positive and promising behavior for application in the area of metallic implants. Full article
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15 pages, 8959 KiB  
Article
Craniofacial Reconstruction with Personalized Lightweight Scaffold Fabricated Using Electron-Beam Additive Manufacturing
by Khaja Moiduddin, Syed Hammad Mian, Sherif Mohammed Elseufy, Basem Motea Abdullah Abdo, Mohamed Kamaleldin Aboudaif and Hisham Alkhalefah
Metals 2022, 12(4), 552; https://doi.org/10.3390/met12040552 - 24 Mar 2022
Cited by 4 | Viewed by 2336
Abstract
Implants are the most popular option for restoring the facial anatomy in the event of a mishap. The commercially available craniofacial implants are of standard shapes, which need to be tailored and shaped to accurately fit the patient’s anatomy. The manual shaping of [...] Read more.
Implants are the most popular option for restoring the facial anatomy in the event of a mishap. The commercially available craniofacial implants are of standard shapes, which need to be tailored and shaped to accurately fit the patient’s anatomy. The manual shaping of the implant to match the bone contours is conducted during surgical operation, and is a cumbersome and inaccurate process. Recent breakthroughs in computer-aided design, analysis, and additive manufacturing (AM) have allowed the precise and rapid manufacture of bespoke scaffolds for difficult anatomical restoration. The goal of this research is to investigate the use of scaffolds for craniofacial reconstruction and their fabrication using electron-beam additive manufacturing (EBAM). Personalized cheekbone scaffolds are additively fabricated using Ti6Al4V and subjected to compression testing. Finally, the scaffold design with the highest compressive strength is subjected to biomechanical analysis. The biomechanical analysis results indicate that the maximum Von Mises stress (40 MPa) and equivalent strain (0.4 µm) are significantly low in magnitude, thus providing a desirable implant that is both flexible and stable. The custom-designed cheekbone scaffold manufactured with AM technology not only aids in bone-implant ingrowth but also helps in reducing implant weight and ensuring implant stability and long-term effectiveness. Full article
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