3D-Bioprinted Organs-on-Chips for Clinical Application
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".
Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 26153
Special Issue Editor
Special Issue Information
Dear Colleagues,
3D-bioprinting technology has been rapidly advanced in the new era of the fourth industrial revolution. To date, many recent studies have demonstrated preliminary 3D-bioprinting technologies that achieved the layer-by-layer assembly of multiple types of cells and extracellular matrices with highly precise spatial distrubution. Applying computer-aided design technology enabled to manufacture even more complex organs or tissues simulating their own functions. Owing to the capacity to integrate a desired 3D cellular arrangement with tissue-specific functions in a micro-scale, 3D-bioprinting has been proposed as a promising strategy for the fabrication of versatile organs-on-chips. Organ-on-a-chip is a microengineered biomimetic system that presents pathophysiological microenvironments, which can greatly facilitate the development of unprecedented medical devices for drug-screening, precision and personalized medicine, as well as in vitro diagnosis. In this Special Issue, we invite the experts outstanding in the multidisciplinary fields of biomedical engineering to discuss various 3D-bioprinting technologies employed to fabricate organs-on-chips for diverse purposes in clinical application. Technological breakthroughs including the incorporation with mechanical and/or electrical stimulatory modules and cell-laden-microfluidic biosensors are also of interst, which can provide the future perspectives in the field of 3D-bioprinted organs-on-chips.
Prof. Dr. Jae Min Cha
Guest Editor
Manuscript Submission Information
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Keywords
- 3D-bioprinting
- Organ-on-a-chip
- Clinical application
- Mechanical stimulation
- Electrical stimulation
- Microfluidic biosensor
- Drug screening
- Precision and personalized medicine
- In vitro diagnosis