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Micromachines
Special Issues
Advanced Micro/Nano Biodegradable Sensors
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Advanced Micro/Nano Biodegradable Sensors

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "E：Engineering and Technology".

Deadline for manuscript submissions: closed (20 September 2021) | Viewed by 6896

Special Issue Editor

Dr. Jahyun Koo

E-Mail Website
Guest Editor
School of Biomedical Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea
Interests: biodegradable materials; neural sensors; electro-medicine

Special Issue Information

Dear Colleagues,

Recent advances in biodegradable sensors introduced unusual classes of electronic devices, which dissolve, disintegrate, or otherwise physically or chemically decompose in a designed period without harmful residue. This biodegradable technology may enable eco-electronics that minimize electronic wastes or provide a new class of implantable bio-sensors that are able to temporarily monitor bio-activity in the body. Such types of biodegradable sensors can eliminate secondary surgery to remove it after medical treatments.

Despite these attractive advantages and versatile applications, the fabrication process is very limited due to biodegradable characteristics of soft organic materials and ultra-thin inorganic membranes during conventional solvent or high-temperature process. We need to discuss the strategy of surface chemistry and mechanical design as biodegradable sensors. Also, there is little research showing this type of device being used in specific organs in the field of biocompatibility.

For this Special Issue, you are invited to submit contributions describing the development in the broad area of biodegradable sensors, ranging from nanoscale to macroscale in dimensions. The scope covers dissolution chemistry, materials processing, sensor structure, design strategy, and bio-compatibility for potential applications of biodegradable electronics.

Dr. Jahyun Koo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biodegradable sensors
  • Physical sensors
  • Chemical sensors
  • MEMM/NEMS sensors
  • Degradation chemistry
  • Biocompatibility

Published Papers (2 papers)

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Review

17 pages, 2516 KiB  
Review
Principles for Controlling the Shape Recovery and Degradation Behavior of Biodegradable Shape-Memory Polymers in Biomedical Applications
by Junsang Lee and Seung-Kyun Kang
Micromachines 2021, 12(7), 757; https://doi.org/10.3390/mi12070757 - 27 Jun 2021
Cited by 17 | Viewed by 3304
Abstract
Polymers with the shape memory effect possess tremendous potential for application in diverse fields, including aerospace, textiles, robotics, and biomedicine, because of their mechanical properties (softness and flexibility) and chemical tunability. Biodegradable shape memory polymers (BSMPs) have unique benefits of long-term biocompatibility and [...] Read more.
Polymers with the shape memory effect possess tremendous potential for application in diverse fields, including aerospace, textiles, robotics, and biomedicine, because of their mechanical properties (softness and flexibility) and chemical tunability. Biodegradable shape memory polymers (BSMPs) have unique benefits of long-term biocompatibility and formation of zero-waste byproducts as the final degradable products are resorbed or absorbed via metabolism or enzyme digestion processes. In addition to their application toward the prevention of biofilm formation or internal tissue damage caused by permanent implant materials and the subsequent need for secondary surgery, which causes secondary infections and complications, BSMPs have been highlighted for minimally invasive medical applications. The properties of BSMPs, including high tunability, thermomechanical properties, shape memory performance, and degradation rate, can be achieved by controlling the combination and content of the comonomer and crystallinity. In addition, the biodegradable chemistry and kinetics of BSMPs, which can be controlled by combining several biodegradable polymers with different hydrolysis chemistry products, such as anhydrides, esters, and carbonates, strongly affect the hydrolytic activity and erosion property. A wide range of applications including self-expending stents, wound closure, drug release systems, and tissue repair, suggests that the BSMPs can be applied as actuators on the basis of their shape recovery and degradation ability. Full article
(This article belongs to the Special Issue Advanced Micro/Nano Biodegradable Sensors)
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21 pages, 4221 KiB  
Review
Recent Progress on Bioresorbable Passive Electronic Devices and Systems
by Zhihuan Wei, Zhongying Xue and Qinglei Guo
Micromachines 2021, 12(6), 600; https://doi.org/10.3390/mi12060600 - 22 May 2021
Cited by 9 | Viewed by 3021
Abstract
Bioresorbable electronic devices and/or systems are of great appeal in the field of biomedical engineering due to their unique characteristics that can be dissolved and resorbed after a predefined period, thus eliminating the costs and risks associated with the secondary surgery for retrieval. [...] Read more.
Bioresorbable electronic devices and/or systems are of great appeal in the field of biomedical engineering due to their unique characteristics that can be dissolved and resorbed after a predefined period, thus eliminating the costs and risks associated with the secondary surgery for retrieval. Among them, passive electronic components or systems are attractive for the clear structure design, simple fabrication process, and ease of data extraction. This work reviews the recent progress on bioresorbable passive electronic devices and systems, with an emphasis on their applications in biomedical engineering. Materials strategies, device architectures, integration approaches, and applications of bioresorbable passive devices are discussed. Furthermore, this work also overviews wireless passive systems fabricated with the combination of various passive components for vital sign monitoring, drug delivering, and nerve regeneration. Finally, we conclude with some perspectives on future fundamental studies, application opportunities, and remaining challenges of bioresorbable passive electronics. Full article
(This article belongs to the Special Issue Advanced Micro/Nano Biodegradable Sensors)
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