Automated Bioreactors for Biological and Tissue Regeneration

Dear colleagues,

Bioreactors are a “NOVEL ROOM” that provides the appropriate cell cultures and preservation environment to grow cells and tissues. Bioreactors can provide the necessary chemical and mechanical environment to affect the kinetics and tissue regenerations. Cells depend heavily on bioelectromechanical forces to maintain their functions: the distributions of nutrients and regulatory factors, and system process control. For the reasons we mentioned, a bioreactor is a key technique and process to create informative platforms of stem cells and tissue structures for clinical purposes or biomedical engineering toolboxes. Bioreactor technology has demonstrated enormous potential in biological and tissue engineering applications due to its outstanding advantages, for example, enhanced functional operation, precious peristaltic flow pumping, dynamic three-dimensional regeneration of tissue culture, and automated control environment through manufacturing techniques of the advanced state of the art methods. There are many advancements and breakthroughs developing in the academic/industrial community, and there are a few challenges raised accordingly upon the reactor designs, structures, fabrication, integration, automation, realtime cell monitoring, and applications of bioreactors for all kinds of biological and tissue regeneration. This Special Issue aims to collate and uncover research papers, short communications, perspectives, and insightful review articles from esteemed colleagues that demonstrate: (1) original works on the topic of bioreactors or cell incubators/3D printed platforms based on various kinds of flow-induced gradients and stimuli for tissue regeneration; and (2) new developments and potentials of applying bioreactor technology of any kind in biological and tissue regeneration. The objective of this Special Edition is to provide insightful information concerning technological advancements for researchers in the community.

Prof. Dr. Ki-Taek Lim
Guest Editor

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