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Micromachines
Special Issues
Feature Papers of Micromachines in Biology and Biomedicine 2024
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Feature Papers of Micromachines in Biology and Biomedicine 2024

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 797

Special Issue Editor

Prof. Dr. Nam-Trung Nguyen

E-Mail Website
Guest Editor
Queensland Micro- and Nanotechnology Centre, Griffith University, West Creek Road, Nathan, QLD 4111, Australia
Interests: microfluidics; nanofluidics; micro/nanomachining technologies; micro/nanoscale science; instrumentation for biomedical applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce a new Special Issue entitled “Feature Papers of Micromachines in Biology and Biomedicine 2024”. In recent years, we have cooperated with some excellent scholars/scientific groups and published several very important high-level works, which have already been cited according to Web of Science data. We aim to introduce new insights into the development of science or cutting-edge technology related to micromachines in the fields of biology and biomedicine, which will make a great contribution to the community.

This Special Issue will be a collection of high-quality papers from excellent scholars from around the world. Both original research articles and comprehensive review papers are welcome. The papers will be published, free of charge, with full open access after peer review to benefit both authors and readers.

You are welcome to send short proposals for submissions of feature papers to our Editorial Office ([email protected]) before submission. They will be evaluated by editors first. Please note that selected full papers will still be subjected to a thorough and rigorous peer review.

We look forward to receiving your excellent work.

Prof. Dr. Nam-Trung Nguyen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
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Further information on MDPI's Special Issue polices can be found here.

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Published Papers (1 paper)

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Research

18 pages, 4465 KiB  
Article
Development of a Microbioreactor for Bacillus subtilis Biofilm Cultivation
by Mojca Seručnik, Iztok Dogsa, Lan Julij Zadravec, Ines Mandic-Mulec and Polona Žnidaršič-Plazl
Micromachines 2024, 15(8), 1037; https://doi.org/10.3390/mi15081037 - 15 Aug 2024
Viewed by 568
Abstract
To improve our understanding of Bacillus subtilis growth and biofilm formation under different environmental conditions, two versions of a microfluidic reactor with two channels separated by a polydimethylsiloxane (PDMS) membrane were developed. The gas phase was introduced into the channel above the membrane, [...] Read more.
To improve our understanding of Bacillus subtilis growth and biofilm formation under different environmental conditions, two versions of a microfluidic reactor with two channels separated by a polydimethylsiloxane (PDMS) membrane were developed. The gas phase was introduced into the channel above the membrane, and oxygen transfer from the gas phase through the membrane was assessed by measuring the dissolved oxygen concentration in the liquid phase using a miniaturized optical sensor and oxygen-sensitive nanoparticles. B. subtilis biofilm formation was monitored in the growth channels of the microbioreactors, which were designed in two shapes: one with circular extensions and one without. The volumes of these microbioreactors were (17 ± 4) μL for the reactors without extensions and (28 ± 4) μL for those with extensions. The effect of microbioreactor geometry and aeration on B. subtilis biofilm growth was evaluated by digital image analysis. In both microbioreactor geometries, stable B. subtilis biofilm formation was achieved after 72 h of incubation at a growth medium flow rate of 1 μL/min. The amount of oxygen significantly influenced biofilm formation. When the culture was cultivated with a continuous air supply, biofilm surface coverage and biomass concentration were higher than in cultivations without aeration or with a 100% oxygen supply. The channel geometry with circular extensions did not lead to a higher total biomass in the microbioreactor compared to the geometry without extensions. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Biology and Biomedicine 2024)
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