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Micromachines
Special Issues
Recent Advances in Biosensors and Micro-Nano Biomedical Devices
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Recent Advances in Biosensors and Micro-Nano Biomedical Devices

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: closed (30 May 2024) | Viewed by 1750

Special Issue Editor

Dr. Zhengwei Li

E-Mail Website
Guest Editor
Department of Biomedical Engineering, University of Houston, Houston, TX 77204, USA
Interests: biohybrid living robotics; bioinspired 3D curvy electronics; biosensors and biomedical devices; bioelectronic eeural interfaces; applied mechanics

Special Issue Information

Dear Colleagues,

The crucial utilization of biosensors and micro/nano-biomedical devices is opening the door for a new paradigm of medical applications for healthcare innovation, such as disease identification, drug development, cancer diagnosis and prevention, rehabilitation, point-of-care testing, and human health management. With the advances in sensing technology, micro/nano-manufacturing techniques, and artificial intelligence, a series of novel biosensors and medical devices have rapidly emerged for a wide range of medical applications in the past decade, such as nanophotonic biosensors for cancer detection, hospital-on-chip intelligent biosensors, DNA-based biosensors, micro/nano-devices for nucleic acid testing, immunoassays, and point-of-care testing applications. This Special Issue seeks to showcase research papers, communications, and review articles that focus on the novel design, fabrication, and applications of all kinds of biosensors and medical devices. Emerging biosensing technologies and fundamental biophysical studies on the development of biosensor systems are also welcome.

We look forward to receiving your submissions.

Dr. Zhengwei Li
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • micro/nano-medical devices
  • microfluidics
  • healthcare innovation
  • wearable bioelectronics
  • point-of-care diagnosis
  • biosensing technology

Published Papers (2 papers)

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Research

20 pages, 8927 KiB  
Article
SOI MEMS Electro-Thermal Actuators for Biomedical Applications: Operation in 0.9% NaCl Solution
by Thomas Sciberras, Ivan Grech, Marija Demicoli, Bertram Mallia, Nicholas Sammut and Pierluigi Mollicone
Micromachines 2024, 15(7), 881; https://doi.org/10.3390/mi15070881 - 4 Jul 2024
Viewed by 449
Abstract
In recent years, the immense potential for MEMS devices in the biomedical industry has been understood. It has been determined that, among their many plausible functions, their use may also extend to single human red blood cell diagnostics, whereby biomarkers of quantifiable magnitudes [...] Read more.
In recent years, the immense potential for MEMS devices in the biomedical industry has been understood. It has been determined that, among their many plausible functions, their use may also extend to single human red blood cell diagnostics, whereby biomarkers of quantifiable magnitudes may be detected. Without a doubt, the mechanical and thermal specifications by which potential devices must be able to function are very strict. Among them is the ability to operate while fully submerged in aqueous solutions. In this work, six devices were modelled numerically in deionised (DI) water and 0.9 wt% NaCl solution, the results of which were validated experimentally. The mechanical performance of the different devices when fully submerged in 0.9 wt% NaCl solution is hereby discussed. With the exception of one, all the devices in their current configuration are confirmed to be suitable candidates for biomedical applications. Full article
(This article belongs to the Special Issue Recent Advances in Biosensors and Micro-Nano Biomedical Devices)
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19 pages, 5120 KiB  
Article
A Sensory Feedback Neural Stimulator Prototype for Both Implantable and Wearable Applications
by Federico Mereu, Francesca Cordella, Roberto Paolini, Alessia Scarpelli, Andrea Demofonti, Loredana Zollo and Emanuele Gruppioni
Micromachines 2024, 15(4), 480; https://doi.org/10.3390/mi15040480 - 30 Mar 2024
Viewed by 970
Abstract
The restoration of sensory feedback is one of the current challenges in the field of prosthetics. This work, following the analysis of the various types of sensory feedback, aims to present a prototype device that could be used both for implantable applications to [...] Read more.
The restoration of sensory feedback is one of the current challenges in the field of prosthetics. This work, following the analysis of the various types of sensory feedback, aims to present a prototype device that could be used both for implantable applications to perform PNS and for wearable applications, performing TENS, to restore sensory feedback. The two systems are composed of three electronic boards that are presented in detail, as well as the bench tests carried out. To the authors’ best knowledge, this work presents the first device that can be used in a dual scenario for restoring sensory feedback. Both the implantable and wearable versions respected the expected values regarding the stimulation parameters. In its implantable version, the proposed system allows simultaneous and independent stimulation of 30 channels. Furthermore, the capacity of the wearable version to elicit somatic sensations was evaluated on healthy participants demonstrating performance comparable with commercial solutions. Full article
(This article belongs to the Special Issue Recent Advances in Biosensors and Micro-Nano Biomedical Devices)
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