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Micromachines
Special Issues
Microfluidic Systems for Diagnostic Applications
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Microfluidic Systems for Diagnostic Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B4: Point-of-Care Devices".

Deadline for manuscript submissions: closed (30 August 2021) | Viewed by 3672

Special Issue Editor

Dr. Max M. Gong

E-Mail Website
Guest Editor
Bock Department of Biomedical Engineering, Trine University, University Ave., Angola, IN 46703, USA
Interests: microfluidics; lab-on-a-chip; organ-on-a-chip; global health; cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Diagnostic processes are the cornerstone of our health and wellness, being of critical importance to infectious disease testing, environmental monitoring, food safety monitoring, and other global health areas. Microscale devices have and continue to push the boundaries of innovation in diagnostic technology. These devices are capable of performing analytical tests with an efficiency and quality comparable to conventional methods, but in a much smaller footprint. Microfluidic diagnostic systems can be fabricated from a variety of substrate materials, including thermoplastics, elastomers, paper, glass, and thread. They are also diverse in their chemistry and sensing modalities, employing electrochemical, colorimetric, and plasmonic detection methods among others. This Special Issue will highlight recent advances in the development of microfluidic systems for diagnostic application in global health and other areas related to the improvement of human health.

Dr. Max M Gong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Microfluidics
  • Global Health
  • Diagnostics
  • Point-of-care Diagnostics
  • Lab-on-a-Chip
  • Infectious Disease
  • Environmental Monitoring
  • Food Safety
  • Water Quality

Published Papers (1 paper)

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Research

15 pages, 11855 KiB  
Article
Solution for Mass Production of High-Throughput Digital Microfluidic Chip Based on a-Si TFT with In-Pixel Boost Circuit
by Feng Qin, Kaidi Zhang, Baiquan Lin, Ping Su, Zhenyu Jia, Kerui Xi, Jiandong Ye and Shulin Gu
Micromachines 2021, 12(10), 1199; https://doi.org/10.3390/mi12101199 - 30 Sep 2021
Cited by 9 | Viewed by 2949
Abstract
As one of the most popular research hotspot of lab-on-chip, digital microfluidic (DMF) technology based on the principle of electrowetting has unique advantages of high-precision, low cost and programmable control. However, due to the limitation of electrodes number, the throughput is hard to [...] Read more.
As one of the most popular research hotspot of lab-on-chip, digital microfluidic (DMF) technology based on the principle of electrowetting has unique advantages of high-precision, low cost and programmable control. However, due to the limitation of electrodes number, the throughput is hard to further upgrade. Therefore, active matrix electrowetting-on-dielectric (AM-EWOD) technology is a solution to acquire larger scale of driving electrodes. However, the process of manufacturing of AM-EWOD based on thin-film-transistor (TFT) is complex and expensive. Besides, the driving voltage of DMF chip is usually much higher than that of common display products.In this paper, a solution for mass production of AM-EWOD based on amorphous silicon (a-Si) is provided. Samples of 32 × 32 matrix AM-EWOD chips was designed and manufactured. A boost circuit was integrated into the pixel, which can raise the pixel voltage up by about 50%. Customized designed Printed Circuit Board (PCB) was used to supply the timing signals and driving voltage to make the motion of droplets programmable. The process of moving, mixing and generation of droplets was demonstrated.The minimum voltage in need was about 20 V and a velocity of up to 96 mm/s was achieved. Such an DMF device with large-scale matrix and low driving voltage will be very suitable for POCT applications. Full article
(This article belongs to the Special Issue Microfluidic Systems for Diagnostic Applications)
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