Implantable Wireless Devices

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: closed (20 June 2019) | Viewed by 4759

Special Issue Editors


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Guest Editor
Assistant Professor, Biomedical Engineering, College of Engineering, The University of Arizona, Bioscience Research Laboratories, Bio5, 1230 N Cherry Ave., Tucson, AZ 85721, USA
Interests: soft electronics; neuroscience tools; electronic materials
Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA
Interests: wearable devices; biosensors; flexible electronics; electrochemistry; nanorobotics; Internet of Things; BioMEMS

Special Issue Information

Dear Colleagues,

Recent advances in soft materials, miniaturization of wireless electronics, optoelectronics, and energy harvesting strategies have enabled new classes of implantable devices that match the mechanical properties of their biological hosts. Such properties have paved the way for new approaches in the creation of biointerfaces, sensors, therapeutic devices, and research tools to analyze and manipulate biological systems. To realize the full potential of these new device classes, advancements in energy harvesting, low-power wireless electronics, sensing strategies, drug delivery, closed-loop regulation, chronic encapsulation strategies, cellular-scale light sources and detectors, as well as chronically stable tissue interfaces will elevate our capabilities and ultimately result in next-generation precision telemedicine tools with broad impact on the medical community. With this Special Issue, we aim to present the progress in the field of implantable devices and highlight promising avenues to scalable solutions that could achieve lifetimes that allow applications in human subjects. In addition to the dissemination of original works in the form of full papers and short communications, emerging and established leaders in the field are also invited to contribute commentaries, perspectives, and insightful reviews.

Prof. Dr. Philipp Gutruf
Prof. Dr. Wei Gao
Guest Editors

Manuscript Submission Information

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Keywords

  • soft materials
  • energy harvesting
  • low-power wireless electronics
  • sensing
  • drug delivery
  • closed-loop regulation
  • chronic encapsulation
  • cellular-scale light sources and detectors
  • chronically stable tissue interfaces
  • precision telemedicine
  • digital health

Published Papers (1 paper)

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Research

11 pages, 6755 KiB  
Article
A Wireless Implantable System for Facilitating Gastrointestinal Motility
by Po-Min Wang, Genia Dubrovsky, James C.Y. Dunn, Yi-Kai Lo and Wentai Liu
Micromachines 2019, 10(8), 525; https://doi.org/10.3390/mi10080525 - 9 Aug 2019
Cited by 6 | Viewed by 4336
Abstract
Gastrointestinal (GI) electrical stimulation has been shown in several studies to be a potential treatment option for GI motility disorders. Despite the promising preliminary research progress, however, its clinical applicability and usability are still unknown and limited due to the lack of a [...] Read more.
Gastrointestinal (GI) electrical stimulation has been shown in several studies to be a potential treatment option for GI motility disorders. Despite the promising preliminary research progress, however, its clinical applicability and usability are still unknown and limited due to the lack of a miniaturized versatile implantable stimulator supporting the investigation of effective stimulation patterns for facilitating GI dysmotility. In this paper, we present a wireless implantable GI modulation system to fill this technology gap. The system consists of a wireless extraluminal gastrointestinal modulation device (EGMD) performing GI electrical stimulation, and a rendezvous device (RD) and a custom-made graphical user interface (GUI) outside the body to wirelessly power and configure the EGMD to provide the desired stimuli for modulating GI smooth muscle activities. The system prototype was validated in bench-top and in vivo tests. The GI modulation system demonstrated its potential for facilitating intestinal transit in the preliminary in vivo chronic study using porcine models. Full article
(This article belongs to the Special Issue Implantable Wireless Devices)
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