Micro/Nanotechnologies for Liquid Biopsy
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "E:Engineering and Technology".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 10264
Special Issue Editor
Special Issue Information
Dear colleagues,
The analysis of circulating tumor biomarkers, commonly referred to as “liquid biopsy”, has received a great deal of scientific and clinical interest as a diagnostic/prognostic tool for cancer, which allows the molecular profiling of a tumor via a simple blood draw. Mounting evidence from clinical studies indicates that liquid biopsy biomarkers, including circulating tumor cells (CTCs), exosomes, cell-free DNA (cfDNA), and microRNA, may serve as promising indicators for early disease characterization and monitoring of therapeutic efficacy.
This Special Issue in Micromachines aims to summarize and present analytical developments of liquid biopsy assays across multiple tumor types, with a special focus on the application of micro- and nanotechnologies to realize a significant improvement in the isolation and analysis of tumor biomarkers. Specifically, potential topics include but are not limited to microfluidic biosensors, nanostructured materials, and multifunctional micro/nanoparticles for high-sensitive detection of biomarkers. Original works or review papers demonstrating clinical evidence of the existing micro and nanotechnologies are also welcomed. This Special Issue will highlight the recent progress made in the field of micro/nanoengineering for the detection of tumor biomarkers, and will bring new insight into the successful translation of high in vitro efficiency of the new technologies to clinical analysis.
Dr. Jiyoon Bu
Guest Editor
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Keywords
- liquid biopsy
- circulating tumor cells (CTCs)
- exosomes
- cell-free DNA (cfDNA)
- circulating tumor DNA (ctDNA)
- microRNA (miRNA)
- nanotechnology
- microfabrication
- nanoparticles
- biosensors
- microfluidics
- and nanomaterials
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