COVID-19 Diagnostics in Clinical Applications, Long-Term Effect and Pandemic Controls

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 58

Special Issue Editor


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Guest Editor
Department of Internal and Specialized Medicine, Sapienza University of Rome | la sapienza, Rome, Italy
Interests: colorectal surgery; gastroenterology; ulcerative colitis; inflammatory bowel disease; endoscopy; colorectal cancer surgery; gastrointestinal diseases

Special Issue Information

Dear Colleagues,

Due to the unprecedented public health crises generated by the COVID-19 pandemic, researchers throughout the world rushed to develop tools to detect both its etiological agent, SARS-CoV-2, and humans’ antibody response against it. The expedited development of sensitive and specific RT-qPCR tests to detect SARS-CoV-2 mRNA, in addition to lateral flow rapid antigen and antibody tests, demonstrates the huge efforts as well as preparedness of research groups and biomed companies to fight public health issues. After two years of the COVID-19 pandemic and the expressive amount of data generated in terms of SARS-CoV-2 diagnostics, full-genome molecular characterization, total antibody detection, and neutralizing antibodies, a comprehensive view of the usefulness and specific implementations of these tools, as well as how they changed the course of the pandemic, is needed.

For this Special Issue, we particularly focus our attention on the long-term effects of COVID-19 on our organism, in particular at the pulmonary level. In the mildest forms, healing is complete in about 7–10 days without consequences. In more serious cases, however, lung healing is slower, taking up to 3–6 weeks, and long-term effects can persist. In some people, especially elderly males with previous illnesses, for whom hospitalization in intensive care or a long period of ventilatory support was necessary, a 20% increase in the development of pulmonary fibrosis, a serious alteration, has been documented, as well as irreversible lung function. Furthermore, in people who have had more severe forms of COVID-19 pneumonia, there has been a continuation of respiratory failure which has required continued oxygen therapy.

Dr. Pietro Crispino
Guest Editor

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Keywords

  • long-term effects
  • COVID-19
  • SARS-CoV-2
  • pneumonia

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