Advances in Immunotherapeutics and Vaccines for Protozoan Infections: New Approaches for Old Foes

Dear Colleagues,

Infections caused by protozoan parasites still represent a major health problem in our globalized world. Parasitic infections are emerging and re-emerging in several endemic countries and spreading to non-endemic countries, reflecting the effect of several anthroponotic factors allied with dramatic climate changes. Therefore, tackling protozoan infections is a challenge that requires an integrated and multidisciplinary approach to human and animal health. The One Health concept has provided a framework for understanding and addressing the complex relationships between human and animal health and the environment, in particular, addressing the challenge of neglected zoonotic diseases (NZDs). Despite the great progress made, the classical challenges of these diseases remain and they are associated with few therapeutic options, suboptimal diagnostics,  poor community awareness, and no vaccine to control human or animal disease for the vast majority of protozoan infections.

Thus, for this Special Issue 'Advances in immunotherapeutics and vaccines for protozoan infections: new approaches for old foes', we invite authors to submit their most recent and innovative studies, updating researchers on the latest advances and groundbreaking approaches to understanding the immune response and the development of new therapies against these pathogens.

We welcome both original studies and reviews with a focus on the development of vaccines, alternative therapies to accelerate therapeutical and prophylactic discovery, and surveillance and control strategies.

Dr. Gabriela Santos Gomes
Dr. Armanda Rodrigues
Guest Editors
Dr. Moreno Cláudia
Guest Editor Assistant

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• immunotherapy
• protozoan
• immunomodulation
• parasites
• vaccines
• host–parasite interaction
• One Health
• innovations
• neglected zoonotic diseases