Marine Actinomycetes: The Potential Source of Antimicrobial and Antifouling

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Environmental Microbiology".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2567

Special Issue Editors


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Guest Editor
Department of Pharmaceutics and Microbiology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia
Interests: Antibiotics PCR DNA Sequencing Antimicrobials Antibiotic Resistance Cloning Bacteriology Gel Electrophoresis Antimicrobial Resistance Genetics

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Co-Guest Editor
National Institute of Oceanography and Fisheries, Cairo, Egypt
Interests: antimicrobials antibiotic; resistance bacteriology; microbial molecular biology; molecular microbiology; applied nicrobiology microbiology; cell biology molecular biology

Special Issue Information

Dear Colleagues,

Fouling bacteria are a group of microorganisms that attach to submerged surfaces in aquatic environments and form biofilms, causing a range of problems. Fouling bacteria can attach to the hulls of ships, offshore structures, and underwater equipment, leading to increased drag and reduced efficiency. This results in higher fuel consumption and maintenance costs, as well as reduced speed and maneuverability.

In addition to affecting the efficiency of marine structures, fouling bacteria can also have negative impacts on marine ecosystems. Bacterial biofilms provide a surface for the attachment of other marine organisms, such as algae, barnacles, and mussels. This can lead to the formation of complex biofouling communities that alter marine ecosystems and interfere with the growth and survival of other marine organisms.

Traditional methods of controlling fouling bacteria have relied on the use of antifouling coatings that contain toxic biocides, such as copper and zinc. However, these biocides can have negative environmental impacts, leading to the search for alternative solutions.

In recent years, research has focused on the use of natural antifouling agents derived from marine organisms, such as marine actinomycetes for their ability to produce a diverse range of bioactive compounds. Those found in marine environments are no exception; marine actinomycetes have developed unique biochemical pathways and metabolic processes to adapt and survive due to the harsh conditions of marine environments. These natural agents have the potential to provide a more sustainable and environmentally friendly solution to the problem of fouling bacteria.

Overall, the problem of fouling bacteria is a significant challenge for the shipping industry and marine ecosystems. The development of alternative solutions to control fouling bacteria is critical to minimize the economic and environmental impacts of fouling, and natural antifouling agents derived from marine organisms are a promising area of research.

Marine actinomycetes, especially those that cause fouling, are a growing subject of study, and we encourage leading specialists in the field to send original works that have not been published elsewhere or are not under review by any other journals. This Special Issue will serve as a platform for researchers to present their most current results to the scientific community, and we will do our best to promote, integrate, and disseminate the articles that are published in it. We anticipate that the information presented in this Special Issue will lead to new insights, partnerships, and lines of inquiry.

We will consider works on topics including but not limited to:

  • Natural products produced from marine actinomycetes that have the ability to inhibit bacteria causing fouling;
  • Chemical characterization of antifouling compounds that are obtained from marine actinomycetes;
  • Elucidation of the mechanism of action of natural product compounds active against fouling bacteria.

Dr. Mohamed H. Al-Agamy
Dr. Moaz M. Hamed
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine actinomycetes
  • antimicrobial activity
  • antifouling
  • antimicrobial mechanisms
  • antimicrobial natural products
  • natural isolated compounds

Published Papers (1 paper)

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Review

42 pages, 6144 KiB  
Review
New Insights on Biological Activities, Chemical Compositions, and Classifications of Marine Actinomycetes Antifouling Agents
by Radwa N. Morgan, Amer Al Ali, Mohammad Y. Alshahrani and Khaled M. Aboshanab
Microorganisms 2023, 11(10), 2444; https://doi.org/10.3390/microorganisms11102444 - 29 Sep 2023
Cited by 5 | Viewed by 1994
Abstract
Biofouling is the assemblage of undesirable biological materials and macro-organisms (barnacles, mussels, etc.) on submerged surfaces, which has unfavorable impacts on the economy and maritime environments. Recently, research efforts have focused on isolating natural, eco-friendly antifouling agents to counteract the toxicities of synthetic [...] Read more.
Biofouling is the assemblage of undesirable biological materials and macro-organisms (barnacles, mussels, etc.) on submerged surfaces, which has unfavorable impacts on the economy and maritime environments. Recently, research efforts have focused on isolating natural, eco-friendly antifouling agents to counteract the toxicities of synthetic antifouling agents. Marine actinomycetes produce a multitude of active metabolites, some of which acquire antifouling properties. These antifouling compounds have chemical structures that fall under the terpenoids, polyketides, furanones, and alkaloids chemical groups. These compounds demonstrate eminent antimicrobial vigor associated with antiquorum sensing and antibiofilm potentialities against both Gram-positive and -negative bacteria. They have also constrained larval settlements and the acetylcholinesterase enzyme, suggesting a strong anti-macrofouling activity. Despite their promising in vitro and in vivo biological activities, scaled-up production of natural antifouling agents retrieved from marine actinomycetes remains inapplicable and challenging. This might be attributed to their relatively low yield, the unreliability of in vitro tests, and the need for optimization before scaled-up manufacturing. This review will focus on some of the most recent marine actinomycete-derived antifouling agents, featuring their biological activities and chemical varieties after providing a quick overview of the disadvantages of fouling and commercially available synthetic antifouling agents. It will also offer different prospects of optimizations and analysis to scale up their industrial manufacturing for potential usage as antifouling coatings and antimicrobial and therapeutic agents. Full article
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